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Ergul E.,Ankara Ataturk Teaching and Research Hospital
Bratislavské lekárske listy | Year: 2010

BACKGROUND: Jaundice has been associated with an increased incidence of postoperative hernias, decreased wound and anastomotic bursting pressure, and reduced tissue collagen synthesis. This study is aimed to examine the possible effects of honey supplementation on anastomotic wound healing in obstructive jaundice (OJ) model. METHODS: Eighty wistar-albino rats were divided into four groups as control, OJ, O plus artificial honey and OJ plus honey. Rats were fed with standard rat chow (SRC) in group-I&II, SRC plus 10 mg/kg/day honey in group-4 and SRC plus artificial honey including the same caloric amount with honey in group-3. Colon anastomoses were performed in all groups. Also, common bile duct ligation was performed in group-1, group-2 and group-3. On the postoperative 3rd and 7th days, anastomotic healing was evaluated. RESULTS: The hydroxyproline level was significantly lower in the jaundiced animals compared with the controls and those given honey or artificial honey (p<0.05). The anastomotic bursting pressure results showed a correlation with the hydroxyproline results, and the use of honey significantly increased the bursting pressure compared with that of the bile duct ligated group (p<0.05). CONCLUSION: The oral administration of honey can be considered when attempts at conventional internal drainage fail in obstructive jaundice (Tab. 2, Fig. 6, Ref. 20). Full Text (Free, PDF) www.bmj.sk. Source


Dede H.,Etlik Zubeyde Hanim Womens Health Teaching and Research Hospital | Dolen I.,Etlik Zubeyde Hanim Womens Health Teaching and Research Hospital | Dede F.S.,Etlik Zubeyde Hanim Womens Health Teaching and Research Hospital | Sivaslioglu A.A.,Ankara Ataturk Teaching and Research Hospital
Archives of Gynecology and Obstetrics | Year: 2013

Purpose: The aim of this study is to evaluate the efficacy and the tolerability of three classic antimuscarinic drugs used in the treatment of over active bladder syndrome using clinical data and quality of life tests, and to evaluate the parameters affecting the success of these drugs. Methods: A total of 90 patients with urge urinary incontinence were randomly allocated into three groups either to receive tolterodine (group A), trospium chloride (group B) or oxybutynin (group C). Urogenital distress inventory short form (UDI-6) and Incontinence impact questionnaire short form (IIQ-7) of the Turkish Urogynecology and Pelvic Reconstructive Surgery Association were performed to each patient before and after treatment to evaluate the effectiveness and tolerability of the antimuscarinic drugs. Adverse events were also recorded during treatment. Results: Improved urodynamic test values were recorded after 6 weeks of treatment in each group. Similarly, statistically significant differences were observed in UDI-6 and IIQ-7 test scores before and after treatment. Complete cure was achieved in 86 % of patients in group A; however, complete cure rates were 67 and 80 % in group B and C, respectively. Although, patients reported comparable tolerability against trospium chloride (77 %) and tolterodine (80 %), only 23 % of patients using oxybutynin considered the drug as tolerable. The most common side effect was dry mouth, followed by insomnia. Both dry mouth and insomnia was highest in group C (50 %). One patient (0.3 %) in group B and two patients (0.7 %) in group C reported that they did not want to continue to use the drug. Conclusion: Antimuscarinic medications are very successful in the treatment of urge urinary incontinence; however, the success of treatment is not only limited to clinical improvement. Patients do not regard a drug as successful unless it is tolerable, easy to adapt to the daily life and improve the quality of life even it has very successful clinical outcomes. © 2012 Springer-Verlag Berlin Heidelberg. Source


Ergul E.,Ankara Ataturk Teaching and Research Hospital
Bratislavské lekárske listy | Year: 2012

Echinococcal disease remains a problem within some endemic areas. It usually involves the liver and lungs, but any other organ can potentially be involved. Soft tissue hydatid disease without liver and lung involvement was reported in 2.3 % of patients. This paper presents a case of 35-year-old male patient who was referred to our department with a 9x9x6cm hydatid cyst at psoas muscle. The rarity of the musculoskeletal disease renders the decision making on the favorable treatment quite difficult. Conservative treatment, complete excision and simple drainage have all been suggested as adequate. We advocate total en bloc excision whenever possible (Fig. 2, Ref. 4). Source


Ergul E.,AsKaabat Cad Eser Sitesi B3 BloK | Gozetlik E.O.,Ankara Ataturk Teaching and Research Hospital
Acta Chirurgica Belgica | Year: 2010

Mixed medullary-papillary carcinomas are very rare and still not listed in the WHO classification (1988). The rarity of the co-existence of medullary and papillary carcinoma suggests that these cases represent mere coincidence. Some studies have shown that radiation exposure has induced neoplasia in the two cell types in rats. But we still have limited information about the carcinogenetic effect of laser ablation on the thyroid gland. This report describes the first case of thyroid carcinoma that demonstrated both medullary carcinoma and papillary components in the thyroid, which might occur due to percutaneous thyroid laser ablation. Source


Yalcin S.,Ankara Ataturk Teaching and Research Hospital
Bratislavské lekárske listy | Year: 2010

BACKGROUND: The sacrococcygeal pilonidal disease affects relatively young people, causing much nuisance and many lost working days. The ideal treatment should be simple, allowing a speedy recovery with short hospitalization while affording a permanent cure. Currently, many treatment options are available; unfortunately, none of them is ideal and each has its own recurrence rate. In this study, we wanted to emphasize the effectiveness of sinotomy in sacrococcygeal pilonidal sinus disease by single-surgeon's experience. METHODS: Single-surgeon's experience of 59 pilonidal sinus patients was reviewed at single-institute between July 2005 and December 2006. 2% Prilocaine was injected for local anesthesia and sinotomy technique was performed. All patients were discharged at postoperative second hour and were followed up for a minimum 1 year. RESULTS: Median age of the 59 patients was 24 (14-56) years. Forty-six (77.96%) of them were male and 13 (22.03%) of them were female. Healing completed in 1 month and almost all the patients were able to return to work the following day. We proudly have no recurrence at our mean follow up time of 16 months (range: 12-24 months). Our complication rate was 1.69%. CONCLUSION: Sinotomy has the advantages of simplicity, the possibility to operate under local anesthesia with excellent recurrence rate of 0% (Ref. 9). Full Text (Free, PDF) www.bmj.sk. Source

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