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Zhu F.,Anhui Medical University | Zhu F.,Anhui Provincial Chest Hospital | Ge J.-J.,Anhui Medical University
International Journal of Clinical and Experimental Medicine | Year: 2016

This study aimed to provide theoretical bases for choosing examination methods onpatients with mediastinal lymphadenectasis. The clinical characteristics of 140 patients with unexplained mediastinal lymphadenectasis who received video-assisted mediastinoscopy (VAM) were reviewed retrospectively. The relationship between various factors and pathological results of mediastinal lymphadenectasis was analyzed. There were no severe complications or death in these patients. The average operation time was 75.00±33.22 min and average blood loss was 55.07±14.13 ml. Pathological results showed that there were 74 malignant cases and 66 benign cases. The accuracy, sensitivity and specificity of VAM were 97.9%, 98.6% and 100% in identifying causes of mediastinal lymphadenectasis, respectively. These findings demonstrated that: 1) VAM is minimally invasive, safe and effective for the diagnosis and treatment of mediastinal lymphadenectasis. 2) During the diagnosis and staging of lung cancer or unexplained mediastinal lymphadenectasis with pulmonary abnormalities, endobronchial ultrasound-guided transbronchial needle aspiration may be applied first, and VAMis indicative for further diagnosis if negative results are found. 3) If patients with mediastinal lymphadenectasis have nopulmonary abnormalities or mediastinal neoplasm, VAMis preferred for examination. © 2016, E-Century Publishing Corporation. All rights reserved.

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