Anhui Agricultural University
Hefei, China

Anhui Agricultural University is a Chinese institution of higher learning located in the urban area of Hefei, the provincial capital of Anhui Province, China. As A Jointly-Funded University By Anhui Provincial People's Government And The Ministry of Agriculture of the PRC. It excels in agricultural, forestry and life science, and covers engineering, science, economics, business, literature, law and medicine.The origin of the university dated back to 1928, when Anhui Provincial University was founded. In 1935, the school of agriculture was formed. In 1954, the agricultural branch was separated, and became an independent institution. The school adopted its current name, "Anhui Agricultural University", in 1995. Wikipedia.

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Si J.,Hefei University | Yang H.,Anhui Agricultural University
Materials Chemistry and Physics | Year: 2011

Bio-compatible and superparamagnetic Fe3O 4@Polydopamine nanocomposites with well-defined core/shell nanostructures have been successfully synthesized by using an in situ self-polymerization method. The size of the core/shell product can be controlled by varying the size of the central Fe3O4 core, and different thicknesses of the PDA shells are obtained by tuning the dopamine monomer concentration. The morphology, phase composition and crystallinity of the as-prepared nanocomposites have been characterized by transmission electron microscopy (TEM) and powder X-ray diffraction (XRD). The 5-dimethylthiazol-2-yl- 2,5-diphenyl-tetrazolium bromide (MTT) cytotoxic analysis shows that the product is biocompatible, with a low toxicity. These unique core/shell materials would be applied in catalyst supports or drug delivery. © 2011 Elsevier B.V. All rights reserved.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SFS-13-2015 | Award Amount: 6.43M | Year: 2016

MycoKey aims to generate innovative and integrated solutions that will support stakeholders in effective and sustainable mycotoxin management along food and feed chains. The project will contribute to reduce mycotoxin contamination mainly in Europe and China, where frequent and severe mycotoxin contaminations occur in crops, and where international trade of commodities and contaminated batches are increasing. MycoKey will address the major affected crops maize, wheat and barley, their associated toxigenic fungi and related mycotoxins (aflatoxins, deoxynivalenol, zearalenone, ochratoxin A, fumonisins). The project will integrate key information and practical solutions for mycotoxin management into a smart ICT tool (MycoKey App), providing answers to stakeholders, who require rapid, customized forecasting, descriptive information on contamination risk/levels, decision support and practical economically-sound suggestions for intervention. Tools and methodologies will be strategically targeted for cost-effective application in the field and during storage, processing and transportation. Alternative and safe ways to use contaminated batches will be also delivered. The focus of Mycokey will be: i) innovating communications of mycotoxin management by applying ICT, providing input for legislation, enhancing knowledge and networks; ii) selecting and improving a range of tools for mycotoxin monitoring; iii) assessing the use of reliable solutions, sustainable compounds/green technologies in prevention, intervention and remediation. The multi-disciplinary consortium, composed by scientific, industrial and association partners (32), includes 11 Chinese institutions and will conduct the 4 years programme in a framework of international networks.

Song C.,University of North Carolina at Chapel Hill | Song C.,Anhui Agricultural University
Progress in Physical Geography | Year: 2013

Forests are the most complex terrestrial ecosystem on Earth's land surface, providing vital goods and services upon which the welfare of humanity depends. The quantification of leaves and biomass in forests is critical for understanding the ecological role of forests in the terrestrial ecosystem. Great effort has been dedicated to the mapping of leaf area and biomass using remotely sensed data. This review focuses on the use of optical remote sensing in mapping leaf area index (LAI) and aboveground biomass for forests. Significant progress has been made in mapping LAI in the past few decades. Mapping of LAI started with location-specific empirical approaches and evolved to semi-empirical and biophysical approaches, which can be applied globally. Although there are some biases in the current LAI products, it can be expected that better-quality LAI products will be delivered in the future. At present, mapping biomass remains predominantly empirical because there is no direct physical relationship between reflected energy in visible, near or mid infrared wavelengths and biomass. Mapping biomass relies on the explicit or implicit mapping of forest structural parameters that are related to biomass allometrically. Although optical images have been successfully used in mapping biomass in low biomass areas, it remains a challenge to map biomass in forested areas with high biomass density due to signal saturation. © The Author(s) 2012.

Wang W.,Sun Yat Sen University | Wang W.,Anhui Agricultural University | Xie Z.-P.,Sun Yat Sen University | Staehelin C.,Sun Yat Sen University
Plant Journal | Year: 2014

The expression of chimeric receptors in plants is a way to activate specific signaling pathways by corresponding signal molecules. Defense signaling induced by chitin from pathogens and nodulation signaling of legumes induced by rhizobial Nod factors (NFs) depend on receptors with extracellular lysin motif (LysM) domains. Here, we constructed chimeras by replacing the ectodomain of chitin elicitor receptor kinase 1 (AtCERK1) of Arabidopsis thaliana with ectodomains of NF receptors of Lotus japonicus (LjNFR1 and LjNFR5). The hybrid constructs, named LjNFR1-AtCERK1 and LjNFR5-AtCERK1, were expressed in cerk1-2, an A. thaliana CERK1 mutant lacking chitin-induced defense signaling. When treated with NFs from Rhizobium sp. NGR234, cerk1-2 expressing both chimeras accumulated reactive oxygen species, expressed chitin-responsive defense genes and showed increased resistance to Fusarium oxysporum. In contrast, expression of a single chimera showed no effects. Likewise, the ectodomains of LjNFR1 and LjNFR5 were replaced by those of OsCERK1 (Oryza sativa chitin elicitor receptor kinase 1) and OsCEBiP (O. sativa chitin elicitor-binding protein), respectively. The chimeras, named OsCERK1-LjNFR1 and OsCEBiP-LjNFR5, were expressed in L. japonicus NF receptor mutants (nfr1-1; nfr5-2) carrying a GUS (β-glucuronidase) gene under the control of the NIN (nodule inception) promoter. Upon chitin treatment, GUS activation reflecting nodulation signaling was observed in the roots of NF receptor mutants expressing both chimeras, whereas a single construct was not sufficient for activation. Hence, replacement of ectodomains in LysM domain receptors provides a way to specifically trigger NF-induced defense signaling in non-legumes and chitin-induced nodulation signaling in legumes. © 2014 John Wiley & Sons Ltd.

Ke F.,Suzhou University of Science and Technology | Ke F.,Anhui Agricultural University | Wang L.,Suzhou University of Science and Technology | Zhu J.,Suzhou University of Science and Technology
Nanoscale | Year: 2015

The recovery and reuse of expensive catalysts are important in both heterogeneous and homogeneous catalysis due to economic and environmental reasons. This work reports a novel multifunctional magnetic core-shell gold catalyst which can be easily prepared and shows remarkable catalytic properties in the reduction of 4-nitrophenol. The novel Au-Fe3O4@metal-organic framework (MOF) catalyst consists of a superparamagnetic Au-Fe3O4 core and a porous MOF shell with controllable thickness. Small Au nanoparticles (NPs) of 3-5 nm are mainly sandwiched between the Fe3O4 core and the porous MOF shell. Catalytic studies show that the core-shell structured Au-Fe3O4@MOF catalyst has a much higher catalytic activity than other reported Au-based catalysts toward the reduction of 4-nitrophenol. Moreover, this catalyst can be easily recycled due to the presence of the superparamagnetic core. Therefore, compared to conventional catalysts used in the reduction of 4-nitrophenol, this porous MOF-based magnetic catalyst is green, cheap and promising for industrial applications. © 2015 The Royal Society of Chemistry.

Wang D.,Anhui Agricultural University | Wang Y.,Anhui Agricultural University | Wan X.,Anhui Agricultural University | Yang C.S.,Rutgers University | Zhang J.,Anhui Agricultural University
Toxicology and Applied Pharmacology | Year: 2015

(-)-Epigallocatechin-3-gallate (EGCG), a constituent of green tea, has been suggested to have numerous health-promoting effects. On the other hand, high-dose EGCG is able to evoke hepatotoxicity. In the present study, we elucidated the responses of hepatic major antioxidant enzymes and nuclear factor erythroid 2-related factor 2 (Nrf2) rescue pathway to high-dose levels of EGCG in Kunming mice. At a non-lethal toxic dose (75. mg/kg, i.p.), repeated EGCG treatments markedly decreased the levels of superoxide dismutase, catalase, and glutathione peroxidase. As a rescue response, the nuclear distribution of Nrf2 was significantly increased; a battery of Nrf2-target genes, including heme oxygenase 1 (HO1), NAD(P)H:quinone oxidoreductase 1 (NQO1), glutathione S-transferase (GST), and those involved in glutathione and thioredoxin systems, were all up-regulated. At the maximum tolerated dose (45. mg/kg, i.p.), repeated EGCG treatments did not disturb the major antioxidant defense. Among the above-mentioned genes, only HO1, NQO1, and GST genes were significantly but modestly up-regulated, suggesting a comprehensive and extensive activation of Nrf2-target genes principally occurs at toxic levels of EGCG. At a lethal dose (200. mg/kg, i.p.), a single EGCG treatment dramatically decreased not only the major antioxidant defense but also the Nrf2-target genes, demonstrating that toxic levels of EGCG are able to cause a biphasic response of Nrf2. Overall, the mechanism of EGCG-triggered hepatotoxicity involves suppression of major antioxidant enzymes, and the Nrf2 rescue pathway plays a vital role for counteracting EGCG toxicity. © 2015 Elsevier Inc.

Li P.,Anhui Agricultural University
Genetics and molecular research : GMR | Year: 2012

Phytophthora capsici is a plant pathogenic oomycete that damages numerous crops worldwide. Consequently, interest in research on the genetic structure of this species has grown in recent decades. However, there is little information about P. capsici in eastern China. We investigated the genetic diversity of P. capsici isolates from three large regions of Anhui Province in eastern China based on ISSR-PCR technology. Thirteen random primers were screened and used to amplify DNA from 51 samples. We obtained 158 reproducible ISSR fragments, of which 90% were polymorphic, revealing a high degree of polymorphism among the isolates. Genetic similarity coefficients among all the isolates ranged from 0.56 to 0.94, with a mean of 0.84 based on the ISSR data, indicating a high level of genetic variation in these P. capsici isolates. Cluster analysis using UPGMA indicated that the Anhui isolates were divided into seven groups according to the DNA fingerprints, although there was no correlation between the ISSR group and geographic origin. Isolates from the same location showed no clustering based on the year of sampling. AMOVA partitioned variability among (13.6%) and within populations (86.4%). The gene flow among populations ranged from 2.804 to 4.937, with a mean of 3.545, indicating highly frequent gene exchange. Genetic distances and genetic differentiation were negatively correlated with geographic distances. These results lead us to suggest that this pathogen has considerable evolutionary potential, which will enable it to adapt to and overcome management strategies over time.

Hu X.,Anhui Agricultural University
Genetics and molecular research : GMR | Year: 2010

Cyclins are primary regulators of the activity of cyclin-dependent kinases and play crucial roles in cell cycle progression in eukaryotes. Although extensive studies have revealed the roles of some cyclins and underlying mechanisms in plants, relatively few cyclins have been functionally analyzed in maize. We identified 59 cyclins in the maize genome, distributed on 10 chromosomes; these were grouped into six types by phylogenetic analysis. The cyclin genes in the maize genome went through numerous tandem gene duplications on five chromosomes. However, no segmental duplications, which occur in rice, were found on maize chromosomes. This information allows us to assess the position of plant cyclin genes in terms of evolution and classification, which will be useful for functional studies of maize cyclins.

Zhang L.,Anhui Agricultural University | Wei Y.,Anhui Agricultural University | Zhang J.,Anhui Agricultural University
Anti-Cancer Agents in Medicinal Chemistry | Year: 2014

After water, tea is the most widely consumed beverage. The major active constituents in green tea are catechins, of which epigallocatechin-3-gallate (EGCG) is the most abundant and active compound. Animal experimental studies using EGCG alone or green tea catechins with EGCG being a major component have generated a mounting body of evidence suggesting that EGCG as a naturally occurring compound and commonly consumed beverage ingredient is a promising cancer preventive agent. However, the relationship between green tea consumption and reduced cancer risk seen from epidemiologic studies is not as encouraging as that observed in animal studies and remains inconclusive. In the present article, the achievements using EGCG or green tea catechins for cancer prevention were reviewed, the latest identified anticancer mechanisms of EGCG and the emerging mechanism-based cancer therapies of EGCG were outlined, and the potential reasons for the discrepancy in animal studies and epidemiological studies were tentatively analysed. On the basis of these analyses, it could be anticipated that future intervention trials in humans would be able to achieve consistent cancer prevention effects provided that the timely intervention of EGCG or green tea catechins at appropriate high-dose levels presumably approaching their upper safety limits have had been fully considered. © 2014 Bentham Science Publishers.

The present invention refers to a method and a kit for the diagnosis of a hepatic disease utilizing the sulfydryl-oxidizing property of serum. Sulfydryl can be oxidized by serum, due to the QSOXs and other macromolecules or small molecules in serum. The specific activity of QSOXs in serum can be detected by fluorescent quantification using Amplex UltraRed (AUR), horseradish perioxidase, dithiothreitol, and tween as key reagents. The total dithiol oxidated capacity of the serum can be detected by colorimetric quantification using dithiothreitol, dithio-bis-nitrobenzoic acid, and guanidine hydrochloride as key reagents. The present invention shows that the specific activity of QSOXs in serum and the total dithiol oxidated capacity of the serum can be used for the diagnosis of hepatic disease, wherein the total dithiol oxidated capacity of the serum shows better diagnostic effect. The present invention also refers to a kit for the diagnosis of a hepatic disease, comprising a key reagent including phosphate buffer, Amplex UltraRed (AUR), horseradish perioxidase, dithiothreitol, and tween; or including guanidine hydrochloride, dithio-bis-nitrobenzoic acid, and dithiothreitol, etc.

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