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Jamaica Plain, MA, United States

Pavletic M.M.,Angell Animal Medical Center
Journal of the American Veterinary Medical Association | Year: 2015

Case Description—5 dogs (a Newfoundland, Golden Retriever, Shiba Inu, Staffordshire Terrier, and Vizsla) were referred for evaluation and treatment of unilateral aural hematomas within a week after their formation.Clinical Findings—Aural hematomas involved the left (3) or right (2) ears.Treatment and Outcome—With patients under anesthesia, the aural hematomas were approached surgically from the convex, or lateral, pinnal surface. Two small incisions were used to position a vacuum drain into the incised hematoma cavity. The drain exited at the base of the pinna and adjacent cervical skin. The free end of the drain was attached to a vacuum reservoir for 18 to 21 days. Drains and skin sutures were removed at this time along with the protective Elizabethan collar. All hematomas resolved and surgical sites healed during the minimum 6-month follow-up period. Cosmetic results were considered excellent in 4 of 5 patients. Slight wrinkling of the pinna in 1 patient resulted from asymmetric enlargement of the cartilaginous walls of the hematoma, where vacuum application resulted in a slight folding of the redundant lateral cartilage wall.Clinical Relevance—The described treatment was efficient, economical, and minimally invasive and required no bandaging or wound care. Placement of the drain tubing on the convex (lateral) aspect sheltered the system from displacement by patients with an Elizabethan collar in place. Overall cosmetic results were excellent; asymmetric enlargement of the cartilaginous walls of the hematoma with slight folding of the pinna was seen in 1 patient. © 2015, American Veterinary Medical Association. All rights reserved. Source


Bradshaw T.J.,University of Wisconsin - Madison | Bowen S.R.,University of Washington | Deveau M.A.,Texas A&M University | Kubicek L.,Angell Animal Medical Center | And 6 more authors.
International Journal of Radiation Oncology Biology Physics | Year: 2015

Purpose Imaging biomarkers of resistance to radiation therapy can inform and guide treatment management. Most studies have so far focused on assessing a single imaging biomarker. The goal of this study was to explore a number of different molecular imaging biomarkers as surrogates of resistance to radiation therapy. Methods and Materials Twenty-two canine patients with spontaneous sinonasal tumors were treated with accelerated hypofractionated radiation therapy, receiving either 10 fractions of 4.2 Gy each or 10 fractions of 5.0 Gy each to the gross tumor volume. Patients underwent fluorodeoxyglucose (FDG)-, fluorothymidine (FLT)-, and Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM)-labeled positron emission tomography/computed tomography (PET/CT) imaging before therapy and FLT and Cu-ATSM PET/CT imaging during therapy. In addition to conventional maximum and mean standardized uptake values (SUVmax; SUVmean) measurements, imaging metrics providing response and spatiotemporal information were extracted for each patient. Progression-free survival was assessed according to response evaluation criteria in solid tumor. The prognostic value of each imaging biomarker was evaluated using univariable Cox proportional hazards regression. Multivariable analysis was also performed but was restricted to 2 predictor variables due to the limited number of patients. The best bivariable model was selected according to pseudo-R2. Results The following variables were significantly associated with poor clinical outcome following radiation therapy according to univariable analysis: tumor volume (P=.011), midtreatment FLT SUVmean (P=.018), and midtreatment FLT SUVmax (P=.006). Large decreases in FLT SUVmean from pretreatment to midtreatment were associated with worse clinical outcome (P=.013). In the bivariable model, the best 2-variable combination for predicting poor outcome was high midtreatment FLT SUVmax (P=.022) in combination with large FLT response from pretreatment to midtreatment (P=.041). Conclusions In addition to tumor volume, pronounced tumor proliferative response quantified using FLT PET, especially when associated with high residual FLT PET at midtreatment, is a negative prognostic biomarker of outcome in canine tumors following radiation therapy. Neither FDG PET nor Cu-ATSM PET were predictive of outcome. © 2015 Elsevier Inc. All rights reserved. Source


Peterson N.W.,Angell Animal Medical Center
Compendium (Yardley, PA) | Year: 2011

Early recognition of failure of oxygen delivery and knowledge of how medications can alter oxygen delivery allow clinicians to institute appropriate therapies in a timely manner and can result in improved patient outcomes. Oxygen delivery can be estimated and evaluated using a variety of methods, including arterial blood gas sampling, blood lactate quantification, echocardiography, and direct cardiac output measurement. Delivery can be enhanced by manipulating the components of the oxygen delivery formula. Cardiac output, hemoglobin concentration, oxygen saturation, and oxygen tension can all be improved through therapeutic or pharmacologic intervention. Source


Simone-Freilicher E.,Angell Animal Medical Center | Rupley A.E.,All Pets Medical Center
Veterinary Clinics of North America - Exotic Animal Practice | Year: 2015

Environmental enrichment is of great import to the emotional, intellectual, and physical development of the juvenile psittacine and their success in the human home environment. Five major types of enrichment include social, occupational, physical, sensory, and nutritional. Occupational enrichment includes exercise and psychological enrichment. Physical enrichment includes the cage and accessories and the external home environment. Sensory enrichment may be visual, auditory, tactile, olfactory, or taste oriented. Nutritional enrichment includes variations in appearance, type, and frequency of diet, and treats, novelty, and foraging. Two phases of the preadult period deserve special enrichment considerations: the development of autonomy and puberty. © 2015 Elsevier Inc. Source


Rupley A.E.,All Pets Medical Center | Simone-Freilicher E.,Angell Animal Medical Center
Veterinary Clinics of North America - Exotic Animal Practice | Year: 2015

The goal of this article is to present practical ways to provide a healthier lifestyle to the commonly kept companion psittacine pets. Necessary information for bird owners to provide for the physical and mental health of their bird is presented. This information is exquisitely important for people keeping birds as pets to know and apply. It is the exotic veterinarian's responsibility to educate clients on how to provide properly for the pet's mental and physical well-being. © 2015 Elsevier Inc. Source

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