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Angeles City, Philippines

The Angeles University Foundation , is a private Roman Catholic university in Angeles City, Philippines and it is considered as the premiere university of Central Luzon. It is a non-stock, non-profit educational institution established on May 25, 1962 by Mr. Agustin P. Angeles, Dr. Barbara Y. Angeles and family. After only less than nine years of operation, the Institution was granted University status on April 16, 1971 by the Department of Education, Culture and Sports. It is one of few Philippine universities granted autonomous status, with a number of its degree programs having been duly recognized as Centers of Excellence and Centers of Development by the Commission on Higher Education.Today, AUF has the highest percentage of faculty with graduate degrees in the Central Luzon region, and among the highest in the Philippines. These qualifications are the foundation for its vaunted quality instruction and research, as evidenced by: Autonomous Status since 2003; Institutional Quality Assurance Monitoring and Evaluation certification from the Commission on Higher Education ; Accreditation by the Philippine Accrediting Association of Schools, Colleges and Universities ; ISO 9001-2000 Certification by TUV-SUD; Center of Excellence in Information Technology and Teacher Education as accredited by the Commission on Higher Education; and Center of Development for Computer Engineering and Nursing from the same government arm. Now on its 50th year of operation, AUF has a total of 63 academic programs scattered across 8 colleges excluding a Medical and Law school. Wikipedia.


Pabalan N.,Angeles University Foundation | Francisco-Pabalan O.,Canadian Grain Commission | Jarjanazi H.,Environment Canada | Li H.,Samuel Lunenfeld Research Institute | And 2 more authors.
Molecular Biology Reports | Year: 2012

The Val762Ala polymorphism poly [ADP-ribose] polymerase 1 (PARP1) gene [ADPRT (adenosine diphosphate ribosyltransferase) gene] affects enzymatic activity, which modulates cancer susceptibility among human populations. Individual data on 13,745 cases and 16,947 controls from 28 published case-control studies were re-evaluated. Odds ratios (OR) were estimated for ethnic group, cancer type, smoking joint effects and studies confined to the Hardy-Weinberg equilibrium. We applied subgroup, sensitivity and outlier analyses as well as the Bonferroni correction for multiple testing. The results show strong evidence that the variant (C) allele confers significant increased risk in the Chinese (OR 1.20-1.44, P < 0.0001-0.002), exacerbated by smoking (OR 1.66-2.53, P < 0.0001) and joint interaction with XRCC1 Arg399Gln (OR 1.39, P < 0.0001) as well as adjustment for tumor type (gastric carcinoma ORs 1.39-2.01, P < 0.0001). These significant effects were unaltered following conservative correction for multiple tests. By contrast, this procedure erased the protective significance in Caucasians, but not in two American subgroups, (i) those in the brain tumor category (0.77-0.79, P < 0.0001) and (ii) smokers in the dominant model (OR 0.86, P < 0.0001). These differential findings between the two ethnicities maybe correlated with significantly (P < 0.0001) greater allele frequency of the variant allele (C) among the Chinese compared to Caucasians. Our racial and tissue-specific summary estimates imply consideration of the Val762Ala polymorphism as candidate gene marker for screening cancer patients' best suited for PARP inhibitor therapy. © 2012 Springer Science+Business Media Dordrecht.


Naser E.,National University of Singapore | Mackey S.,National University of Singapore | Arthur D.,Angeles University Foundation | Klainin-Yobas P.,National University of Singapore | And 2 more authors.
Midwifery | Year: 2012

Objectives: to explore the traditional birthing practices of Singaporean women. Research design: a qualitative study using a phenomenological approach. Data were collected using individual interviews, which were audio-recorded and transcribed verbatim. Colaizzi's phenomenological method was used to analyse the data. Setting: obstetric outpatient clinics in a tertiary hospital in Singapore. Participants: a purposive sample of 30 women, 1-3 months postpartum. Findings: two broad themes emerged-following tradition and challenging tradition. Key conclusions: Singaporean women experiencing pregnancy and childbirth follow tradition through the influence of their mother and mother-in-law and because of worry over consequences that may result if they do not. Tradition is also challenged through the modification or rejection of traditional practices and changing family roles and expectations. Implications: health professionals need to provide accurate information on traditional birthing practices and scientific evidence to support or refute such practices with the aim of preventing women from adhering to practices that are hazardous to them and the baby. © 2011 Elsevier Ltd.


Yao X.,Peking Union Medical College | Li Z.,Peking Union Medical College | Arthur D.,Angeles University Foundation | Hu L.,Capital Medical University | Cheng G.,Capital Medical University
International Journal of Mental Health Nursing | Year: 2014

The Violence Risk Screening-10 is one of the few instruments available for evaluating violence risk in mental health clients during and after hospitalization. This prospective study examined the applicability of this brief instrument with a sample of 289 clients in the 6 months after discharge from a general psychiatric hospital in Beijing. During the research period, 24 of the 289 clients demonstrated aggression. The receiver-operator characteristic curve yielded an area under the curve of 0.62. At the cut-off point of 4.5, its sensitivity/specificity was 79.2%/33.3%, and the corresponding positive/negative predictive value was 9.9%/94.5%. The predictive accuracy of this instrument was lower compared with the results of the original study, and was also less accurate than when it was administered while the clients were in the hospital. While promising in its utility for use beyond the hospital, it deserves further modification prior to its wide use across culturally-diverse China. © 2013 Australian College of Mental Health Nurses Inc.


Pabalan N.,Angeles University Foundation | Jarjanazi H.,Environment Canada | Ozcelik H.,Samuel Lunenfeld Research Institute
International Journal of Colorectal Disease | Year: 2013

Purpose: Inconsistency of reported associations between the C1420T polymorphism in the cytosolic serine hydroxymethyltransferase (SHMT1) gene and colorectal cancer (CRC) prompted us to undertake a meta-analysis. Methods: We conducted searches of published literature in MEDLINE through PubMed up to April 2012. Individual data on 5,043 cases and 6,311 controls from 15 published case-control studies were evaluated. Meta-analyses were performed on the compiled dataset. Results: In the overall analysis, association was lacking between the C1420T polymorphism and CRC risk (odds ratio [OR] 0.96-1.04, p = 0.47-0.77), materially unchanged when reanalyzed without the Hardy-Weinberg equilibrium-deviating studies (OR 1.03-1.09, p = 0.22-0.55) or subjected to outlier treatment (OR 0.89-0.99, p = 0.10-0.8). In the ethnic subgroups, Europeans were susceptible (OR 1.11-1.17, p = 0.13-0.48) and Americans, slightly protected (OR 0.86-0.87, p = 0.49-0.61). The increased risk effects, however, became null following outlier treatment (OR 0.95-1.06). Test for interaction between decreased risk associations in the low-folate subgroup (OR 0.60-0.85, p = 0.009-0.03) with the susceptible effects in the high-folate category (OR 1.14-1.22, p = 0.19-0.32) was significant (p interaction = 0.004). Conclusions: Overall summary estimates imply no associations but suggest geography-specific effects of the SHMT1 polymorphism that render Europeans susceptible, but not Americans. Folate status appears to show an inverse association of this polymorphism with CRC. © 2013 Springer-Verlag Berlin Heidelberg.


Pabalan N.,Angeles University Foundation
Molecular biology reports | Year: 2012

The Val762Ala polymorphism poly [ADP-ribose] polymerase 1 (PARP1) gene [ADPRT (adenosine diphosphate ribosyltransferase) gene] affects enzymatic activity, which modulates cancer susceptibility among human populations. Individual data on 13,745 cases and 16,947 controls from 28 published case-control studies were re-evaluated. Odds ratios (OR) were estimated for ethnic group, cancer type, smoking joint effects and studies confined to the Hardy-Weinberg equilibrium. We applied subgroup, sensitivity and outlier analyses as well as the Bonferroni correction for multiple testing. The results show strong evidence that the variant (C) allele confers significant increased risk in the Chinese (OR 1.20-1.44, P < 0.0001-0.002), exacerbated by smoking (OR 1.66-2.53, P < 0.0001) and joint interaction with XRCC1 Arg399Gln (OR 1.39, P < 0.0001) as well as adjustment for tumor type (gastric carcinoma ORs 1.39-2.01, P < 0.0001). These significant effects were unaltered following conservative correction for multiple tests. By contrast, this procedure erased the protective significance in Caucasians, but not in two American subgroups, (i) those in the brain tumor category (0.77-0.79, P < 0.0001) and (ii) smokers in the dominant model (OR 0.86, P < 0.0001). These differential findings between the two ethnicities maybe correlated with significantly (P < 0.0001) greater allele frequency of the variant allele (C) among the Chinese compared to Caucasians. Our racial and tissue-specific summary estimates imply consideration of the Val762Ala polymorphism as candidate gene marker for screening cancer patients' best suited for PARP inhibitor therapy.

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