Andrija Stampar Teaching Institute of Public Health

Zagreb, Croatia

Andrija Stampar Teaching Institute of Public Health

Zagreb, Croatia
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Skoko B.,Institute for Medical Research and Occupational Health | Marovic G.,Institute for Medical Research and Occupational Health | Babic D.,Institute for Medical Research and Occupational Health | Sostaric M.,Institute for Medical Research and Occupational Health | Jukic M.,Andrija Stampar Teaching Institute of Public Health
Journal of Environmental Radioactivity | Year: 2017

The aim of this study was to investigate the uptake of 238U, 235U, 232Th, 226Ra, 210Pb and 40K by plants that grow on a coal ash and slag disposal site known for its higher content of naturally occurring radionuclides. Plant species that were sampled are common for the Mediterranean flora and can be divided as follows: grasses & herbs, shrubs and trees. To compare the activity concentrations and the resultant concentration ratios of the disposal site with those in natural conditions, we used control data specific for the research area, obtained for plants growing on untreated natural soil. Radionuclide activity concentrations were determined by high resolution gamma-ray spectrometry. Media parameters (pH, electrical conductivity and organic matter content) were also analysed. We confirmed significantly higher activity concentrations of 238U, 235U, 226Ra and 210Pb in ash and slag compared to control soil. However, a significant increase in the radionuclide activity concentration in the disposal site's vegetation was observed only for 226Ra. On the contrary, a significantly smaller activity concentration of 40K in ash and slag had no impact on its activity concentration in plant samples. The calculated plant uptake of 238U, 235U, 226Ra and 210Pb is significantly smaller in comparison with the uptake at the control site, while it is vice versa for 40K. No significant difference was observed between the disposal site and the control site's plant uptake of 232Th. These results can be the foundation for further radioecological assessment of this disposal site but also, globally, they can contribute to a better understanding of nature and long-term management of such disposal sites. © 2017 Elsevier Ltd


Kuzman M.,Andrija Stampar Teaching Institute of Public Health | Posavec M.,Andrija Stampar Teaching Institute of Public Health
Psychiatria Danubina | Year: 2016

Background: At the drug scene some major shifts were observed, more and more reports highlighted the abuse of prescription medication. Despite the importance of controlled medication in treatment child and adolescent disorders, this increase may be a factor which influence misuse and nonmedical use of prescribed drugs among adolescents. Subject and methods: Croatian data from ESPAD survey in 2003, 2007 and 2011 were used, and variables selected from the international ESPAD questionnaire. Dependent variable was taking tranquilizers or sedatives prescribed by doctor in the past 12 months. Independent variables were nonmedical use of tranquilizers/sedatives, use of other psychoactive substances, school performance, truancy, delinquent behaviour, satisfaction with relationships with parents, friends, health, self-perception, financial situation and symptoms of depression. The respondents were 8849 students (4393 boys and 4456 girls) in three consecutive ESPAD surveys (2003, 2007 and 2011). Results: In multivariate analysis for all three survey years the strongest predictor for prescription medication use was use of sedatives/tranquilizers without prescription (OR 6.14; CI 4.08-9.23; OR 8.16; CI4.65-14.32; OR 9.77; CI5.92-15.13). Frequent drinking and excessive drinking or drunkenness also predicted prescription medication use, (OR 1.85; CI1.10-3.10; OR 2.01: CI 1.20-3.39). Among other problem behaviours lower school performance (OR 2.92; CI 1.41-6.05; OR 2.56; CI 1.12-5.87), missed school days OR 1.59; OR1.01-2.51; OR1.72; CI 1.03-2.87), aggressive behaviour (OR 1.532; CI 1.01-2.28; OR1.65; CI 1.04-2.62), depressive symptoms (OR 2.19; CI 1.24-3.85) and poorer financial situation were connected with prescription medication use. Conclusion: Prescription use of tranquilizers/sedatives was predicted by nonmedical tranquilizers/sedatives use, alcohol abuse, symptoms of depression and variables indicating maladjusted behaviour. Although there is sufficient evidence that prescription medication abuse might went unobserved, the further analysis which could better explain its' role and impact is still needed. © Medicinska naklada - Zagreb, Croatia.


Jukic M.,Andrija Stampar Teaching Institute of Public Health | Curkovic L.,University of Zagreb | Sabaric J.,Andrija Stampar Teaching Institute of Public Health | Kerolli-Mustafa M.,International Business College Mitrovica
Bulletin of Environmental Contamination and Toxicology | Year: 2017

The aim of this study was to extract the wood biomass fly ash fractions by a three-stage sequential extraction method for acetic acid and ion exchangeable (BCR 1), hydroxylamine hydrochloride reduction (BCR 2), and hydrogen peroxide oxidation (BCR 3) fractions in order to access the leaching behavior of this residue. The fly ash was collected as a by-product from the processing of mixed wood biomass in Udbina combustion facility, Croatia. Concentrations of several elements (As, Cd, Cr, Cu, Ni, Pb and Zn) in all extracts were determined by inductively coupled plasma atomic emission spectrometry. The acidic exchangeable form of the metals was used to evaluate the potential ecological risk of biomass fly ash. According to calculated potential ecological risk index, it is confirmed that mobility of Ni and As has major environmental impact. However the results of potential ecological risk show that biomass fly ash had a low risk. © 2017 Springer Science+Business Media, LLC


PubMed | University of Zagreb, Ruder Boskovic Institute, Andrija Stampar Teaching Institute of Public Health and Institute for Medical Research and Occupational Health
Type: Journal Article | Journal: Environmental science and pollution research international | Year: 2015

The proliferation of silver nanoparticle (AgNP) production and use owing to their antimicrobial properties justifies the need to examine the resulting environmental impacts. The discharge of biocidal nanoparticles to water bodies may pose a threat to aquatic species. This study evaluated the effects of citrate-coated AgNPs on the standardized test organism Daphnia magna Straus clone MBP996 by means of biochemical biomarker response. AgNP toxicity was compared against the toxic effect of Ag(+). The toxicity endpoints were calculated based upon measured Ag concentrations in exposure media. For AgNPs, the NOAEC and LOAEC values at 48 h were 5 and 7 g Ag/L, respectively, while these values were 0.5 and 1 g Ag/L, respectively, for Ag(+). The EC50 at 48 h was computed to be 12.40.6 and 2.60.1 g Ag/L for AgNPs and Ag(+), respectively, with 95 % confidence intervals of 12.1-12.8 and 2.3-2.8 g Ag/L, respectively. These results indicate significant less toxicity of AgNP compared to free Ag(+) ions. Five biomarkers were evaluated in Daphnia magna neonates after acute exposure to Ag(+) or AgNPs, including glutathione (GSH) level, reactive oxygen species (ROS) content, and catalase (CAT), acetylcholinesterase (AChE), and superoxide dismutase (SOD) activity. AgNPs induced toxicity and oxidative stress responses in D. magna neonates at tenfold higher concentrations than Ag. Biochemical methods revealed a clear increase in AChE activity, decreased ROS level, increased GSH level and CAT activity, but no significant changes in SOD activity. As Ag(+) may dissolve from AgNPs, these two types of Ag could act synergistically and produce a greater toxic response. The observed remarkably high toxicity of AgNPs (in the parts-per-billion range) to crustaceans indicates that these organisms are a vulnerable link in the aquatic food chain with regard to contamination by nanosilver. Graphical Abstract .


PubMed | Vindija d.d, Andrija Stampar Teaching Institute of Public Health and University of Zagreb
Type: | Journal: Ultrasonics sonochemistry | Year: 2016

Ultrasonication is a nonthermal food processing technology that is used in several applications (extraction, pretreatment before drying, freezing, inactivation of microorganisms etc.). The objective of this study was to investigate the effect of high power ultrasound and pasteurisation on the aroma profile and sensory properties of cranberry juice and nectar. Samples were treated according to the experimental design, with high power sonicator at ultrasound frequency of 20kHz under various conditions (treatment time 3, 6 and 9min, sample temperature: 20, 40 and 60C and amplitude 60, 90 and 120m). The aromatic profiles of juices showed that, compared to the untreated samples of juices and nectars, the ultrasonic treatment led to the formation of new compounds or to the disappearance of compounds that were found in the untreated samples. Samples treated at the highest amplitude (120m) were used for evaluation and comparison with untreated and pasteurised samples using electronic tongue study. Principle component analysis (PCA) confirmed the results of electronic tongue study, which showed that the ultrasound-treated and pasteurised juices had different scores compared to the untreated samples. Sensory evaluation showed that ultrasonically treated and pasteurised juices received lower scores in comparison with the untreated samples.


Momirovic A.,Andrija Stampar Teaching Institute of Public Health | Gjuric H.,Andrija Stampar Teaching Institute of Public Health | Goluban M.,Andrija Stampar Teaching Institute of Public Health
Psychiatria Danubina | Year: 2014

Background: The series of personality questionnaires constructed using a computer was created on the basis of cybernetic theories of personality, which presupposes the existence of six conative control systems: a system for the regulation of defense responses, a system for the regulation of attack responses, a system for controlling physiological functions, a system for coordination of regulatory functions, system for integration of regulatory functions and system for regulation of activity. Six personality questionnaires measure the intensity of the following pathological personality tendencies: 1. neurasthenia and anxiety, 2. aggressiveness and impulsiveness, 3. conversive neurotic disorders, 4. psychotic dissociation, 5. psychotic regression and 6. extroversionintroversion. Subjects and methods: The sample consisted of 4368 persons: 3496 subjects without a diagnosis, and 872 patients with a psychiatric diagnosis. Participants had to fill in the six personality questionnaire. Data were collected anonymously, during psychological treatment at the Neuropsychiatric Hospital "Dr. Ivan Barbot" in Popovača, at the Department of Occupational Medicine and Transport and the Department of Mental Health and Addiction Prevention at Dr. Andrija Štampar Institute of Public Health and for the purpose of selection of candidates for employment in the period from 1984 until today. Basic metric characteristics were determined for all scales. Factor structure of the scales was determined using principal component analysis; as canonical discriminant analysis, polar taxons analysis and canonical correlation analysis are special cases of factor analysis, results of factor analysis were used for further processing. Results: Results from earlier studies are replicated on much larger sample: metric characteristics of scales are very good, as in previous studies, similar structure of polar taxons was found and discrimination between healthy subjects ad those with psychiatric diagnoses was successful. Canonical correlation analysis showed interconnection of reactions on certain scales and extremely complex relationship between them which indirectly confirms the theoretical model on the basis of which the scales are formed. Conclusions: The usefulness of this scales is confirmed in clinical setting and in selection of candidates for employment. © Medicinska naklada - Zagreb, Croatia


PubMed | Andrija Stampar Teaching Institute of Public Health
Type: Journal Article | Journal: Journal of infection in developing countries | Year: 2016

Mosquito control in the Zagreb area has been conducted for many years, whereas the fauna has only been investigated in the last 20 years. So far 30 mosquito species have been detected in the city area. Culex pipiens form molestus is the dominant mosquito species in indoor breeding sites. In forested areas and areas exposed to flooding, the active period is early spring and the dominant species are Ochlerotatus sticticus, Ochlerotatus cantans, Ochlerotatus geniculatus and Aedes vexans. The eudominant mosquito species found in the artificial breeding sites are Culex pipiens and the Asian tiger mosquito, Aedes albopictus. Invasive Ae. albopictus, present in the Zagreb area since 2004, has expanded to a larger area of the city during the last three years. The recent emergence of the human West Nile virus and Usutu virus neuroinvasive disease in Zagreb and its surroundings highlighted the role of mosquitoes as vectors of emerging arboviruses. The paper focuses on mosquito species and arboviral infections detected in humans and animals in the Zagreb area, Croatia.


PubMed | Andrija Stampar Teaching Institute of Public Health
Type: Journal Article | Journal: Psychiatria Danubina | Year: 2016

At the drug scene some major shifts were observed, more and more reports highlighted the abuse of prescription medication. Despite the importance of controlled medication in treatment child and adolescent disorders, this increase may be a factor which influence misuse and nonmedical use of prescribed drugs among adolescents.Croatian data from ESPAD survey in 2003, 2007 and 2011 were used, and variables selected from the international ESPAD questionnaire. Dependent variable was taking tranquilizers or sedatives prescribed by doctor in the past 12 months. Independent variables were nonmedical use of tranquilizers/sedatives, use of other psychoactive substances, school performance, truancy, delinquent behaviour, satisfaction with relationships with parents, friends, health, self-perception, financial situation and symptoms of depression. The respondents were 8849 students (4393 boys and 4456 girls) in three consecutive ESPAD surveys (2003, 2007 and 2011).In multivariate analysis for all three survey years the strongest predictor for prescription medication use was use of sedatives/tranquilizers without prescription (OR 6.14; CI 4.08-9.23; OR 8.16; CI4.65-14.32; OR 9.77; CI5.92-15.13). Frequent drinking and excessive drinking or drunkenness also predicted prescription medication use, (OR 1.85; CI1.10-3.10; OR 2.01: CI 1.20-3.39). Among other problem behaviours lower school performance (OR 2.92; CI 1.41-6.05; OR 2.56; CI 1.12-5.87), missed school days OR 1.59; OR1.01-2.51; OR1.72; CI 1.03-2.87), aggressive behaviour (OR 1.532; CI 1.01-2.28; OR1.65; CI 1.04-2.62), depressive symptoms (OR 2.19; CI 1.24-3.85) and poorer financial situation were connected with prescription medication use.Prescription use of tranquilizers/sedatives was predicted by nonmedical tranquilizers/sedatives use, alcohol abuse, symptoms of depression and variables indicating maladjusted behaviour. Although there is sufficient evidence that prescription medication abuse might went unobserved, the further analysis which could better explain its role and impact is still needed.


PubMed | Andrija Stampar Teaching Institute of Public Health
Type: Journal Article | Journal: Psychiatria Danubina | Year: 2016

Perseverance in applying the therapy is an important determinant of its success, but evaluation of perseverance is extremely complex, and therefore, alternative method of processing the results by the Culigs questionnaire of perseverance is presented.Psychometric properties of the questionnaire on a sample of 225 examinees have been calculated and the factor structure of indicators that make up the scale is presented.Psychometric properties calculated in an alternative way are significantly better than the original, especially when it comes to reliability and representativeness of the questionnaire.This method of data analysis raises the possibility of multivariate data processing on the Culigs questionnaire, which is important for further research.


Sostar Z.,Andrija Stampar Teaching Institute of Public Health
Psychiatria Danubina | Year: 2014

Background: Injuries are common during sport activities, a part of which is also injuries to the stomatognathic system. According to the data from literature orofacial injuries are frequent, but relatively minor. World Dental Federation has listed basketball as a medium-risk sport in sustaining orofacial injuries. The purpose of this investigation was to determine incidence, type and severity of orofacial injuries during basketball and frequents of mouthguard use. Subject and methods: The sample consisted of 195 athletes who actively participate in basketball, 60 amateurs/non-professional and 135 professionals. Results: A total of 2 265 injuries to the stomatognathic system were documented in this research; 200 (8.8%) of those injuries refer to the non-professionals and 2 065 (91.2%) to the professionals. The most common injuries are lacerations and contusions of soft tissue (a total of 2 208 or 97.5%), followed by dental injuries (a total of 57 or 2.5%). Out of all recorded laceration injuries 59.8% lacerations of soft tissue occurred during practice (12.6% amateurs and 87.4% professionals), while 40.2% of them occurred during games (2.5% amateurs and 97.5% professionals). Of a total of 57 dental injuries recorded during an athletes career, in 78.9% it were the professionals who suffered an injury, and in 21.1% of them the amateurs. Out of a total of 195 basketball players only 1% (2 players - one professional and one amateur) frequently used mouthguard during practice and games, while 93.3% of them never tried to wear a mouthguard. Such low percentage of mouthguard use in basketball players reflects poor awareness and education of athletes and coaches, as well as insufficient role of dentists in education. Conclusions: Orofacial injuries during basketball are not severe (80% lacerations), and therefore do not stimulate the use of a protecting devices even their use will totally diminish this type of injuries. © Medicinska naklada - Zagreb, Croatia

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