Anadys Pharmaceuticals Inc.

San Diego, CA, United States

Anadys Pharmaceuticals Inc.

San Diego, CA, United States

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Patent
Anadys Pharmaceuticals Inc. | Date: 2014-07-31

The invention relates to methods for making deoxyribofuranose compounds such as compound (2) which are useful intermediates in the preparation of pharmaceutical compounds such as 5-amino-3-(2-O-acetyl-3-deoxy--D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and the like.


Patent
Anadys Pharmaceuticals Inc. | Date: 2012-01-23

The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I


Patent
Anadys Pharmaceuticals Inc. | Date: 2013-01-22

The present invention relates to a semi-continuous or continuous process for the regioselective enzymatic hydrolysis of alcohol groups protected e.g. as esters or amino-acid esters or phosphate groups. The process of the present invention is useful for instance for the selective enzymatic hydrolysis of pyranosides or furanosides having more than one hydrolysable groups.


The invention is directed to [1,2,4]thiadiazine 1,1-dioxide compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.


Patent
Anadys Pharmaceuticals Inc. | Date: 2014-06-10

The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.


The invention is directed to a method of treating infections by hepatitis C virus by administering N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0^(2,7)]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1^(6)-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.


Patent
Anadys Pharmaceuticals Inc. | Date: 2012-08-06

The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I


The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.


Patent
Anadys Pharmaceuticals Inc. | Date: 2013-12-10

The invention relates to a method for treating disease such as viral infections, tumors, and cancers, comprising administering a TLR7 agonist or TLR7 agonist prodrug according to a cyclical dosing schedule having a dosing period and a resting period. For example, the method encompasses treating disease with: 5-amino-3-(2-O-acetyl-3-deoxy--D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one Tosylate according to a dosing schedule of every-other-day or a dosing schedule of three consecutive days of dosing followed by four consecutive days of not dosing.


Patent
Anadys Pharmaceuticals Inc. | Date: 2013-09-30

The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I wherein and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

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