Emeryville, CA, United States
Emeryville, CA, United States

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Patent
Amyris Biotechnologies Inc. | Date: 2016-09-09

Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. In some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker.


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-02-03

Provided is a polyolefin-based resin composition including a hydrogenated block copolymer (A) and a polyolefin-based resin (B), the hydrogenated block copolymer (A) being a hydrogenated product of a block copolymer including a polymer block (a) composed of a constitutional unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a constitutional unit (b1) derived from farnesene and 99 to 0% by mass of a constitutional unit (b2) derived from a conjugated diene other than farnesene; a mass ratio of the polymer block (a) and the polymer block (b) [(a)/(b)] being 1/99 to 55/45; 50 mol% or more of carbon-carbon double bonds in the polymer block (b) being hydrogenated; and a mass ratio of the polyolefin-based resin (B) and the hydrogenated block copolymer (A) [{polyolefin-based resin (B)}/{hydrogenated block copolymer (A)}] being 1/99 to 99/1. The polyolefin-based resin composition is favorable in flexibility and molding processability, excellent in weather resistance and whitening resistance, and also excellent in rigidity.


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-10-19

A thermoplastic elastomer composition comprising 100 parts by mass of a hydrogenated block copolymer (A) comprising a polymer block (a) consisting of a structural unit derived from an aromatic vinyl compound and a polymer block (b) comprising 1 to 100% by mass of a structural unit (b1) derived from farnesene and comprising 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, a mass ratio [(a)/(b)] of the polymer block (a) to the polymer block (b) being 1/99 to 70/30; and 5 to 300 parts by mass of a polar group-containing olefinic polymer (B), is excellent in flexibility and molding processability and capable of adhering to a ceramic, a metal, a synthetic resin, or the like even through a heat treatment at low temperatures (for example, 190C or lower) without requiring a primer treatment or the like.


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-12-14

Provided is an aqueous emulsion including a block copolymer (I) containing a polymer block (a) composed of a structural unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a structural unit (b1) derived from farnesene and 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, with a mass ratio [(a)/(b)] of the polymer block (a) and the polymer block (b) being 5/95 to 70/30; a protective colloid (II); and water, a content of the protective colloid (II) being 3 to 35 parts by mass based on 100 parts by mass of the block copolymer (I).


Patent
The Regents Of The University Of California and Amyris Biotechnologies Inc. | Date: 2016-05-18

The present invention provides genetically modified host cells and use of same for producing isoprenoid compounds.


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-10-19

A resin composition including a hydrogenated block copolymer (A) including a polymer block (a) consisting of a structural unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a structural unit (b1) derived from farnesene and containing 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, 50 mol% or more of a carbon-carbon double bond in the polymer block (b) being hydrogenated; and at least one resin (B) selected from the group consisting of a polyphenylene ether-based resin, a styrene-based resin, an acrylic resin, a polycarbonate-based resin, and a polyamide-based resin.


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-02-03

The thermoplastic elastomer composition of the present invention is a thermoplastic elastomer composition including a hydrogenated block copolymer (A) and a softening agent (B), the hydrogenated block copolymer (A) being a hydrogenated product of a block copolymer including a polymer block (a) composed of a constitutional unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a constitutional unit (b1) derived from farnesene and 99 to 0% by mass of a constitutional unit (b2) derived from a conjugated diene other than farnesene; a mass ratio of the polymer block (a) and the polymer block (b) [(a)/(b)] being 1/99 to 70/30; 50 mol% or more of carbon-carbon double bonds in the polymer block (b) being hydrogenated; and a content of the softening agent (B) being 20 to 2,000 parts by mass on the basis of 100 parts by mass of the hydrogenated block copolymer (A).


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-02-03

The present invention relates to a laminate including an adhesive layer that hardly suffers from adhesive transfer and exhibits a good adhesive strength, and a substrate layer, a protective film including the laminate, and a process for producing the laminate. The laminate of the present invention includes an adhesive layer and a substrate layer, in which the adhesive layer includes a hydrogenated product of a copolymer containing a constitutional unit (a) derived from an aromatic vinyl compound and a constitutional unit (b) derived from a conjugated diene; a content of a constitutional unit (b1) derived from farnesene in a whole amount of the constitutional unit (b) derived from the conjugated diene is from 1 to 100% by mass, and a content of a constitutional unit (b2) derived from a conjugated diene other than farnesene in a whole amount of the constitutional unit (b) derived from the conjugated diene is from 0 to 99% by mass; and a hydrogenation rate of carbon-carbon double bonds in the constitutional unit (b) derived from the conjugated diene is 50 mol% or more.


Patent
Amyris Biotechnologies Inc. | Date: 2016-06-15

The present invention provides methods for a robust production of isoprenoids via one or more biosynthetic pathways. The invention also provides nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods. The invention also provides fermentation methods for high productivity of isoprenoids from genetically modified host cells.


Patent
Kuraray Co. and Amyris Biotechnologies Inc. | Date: 2016-06-29

The present invention provides a rubber composition capable of producing a rubber molded article that is excellent in rolling resistance performance, steering stability, mechanical strength and abrasion resistance, and a tire obtained by using the rubber composition in at least a part thereof. The present invention relates to a rubber composition including (A) a rubber component including at least one rubber selected from the group consisting of a synthetic rubber and a natural rubber, (B) silica and (C) a modified polymer of farnesene obtained by introducing a functional group into a polymer of farnesene, in which a content of the silica (B) in the rubber composition is from 20 to 150 parts by mass on the basis of 100 parts by mass of the rubber component (A), and a content of the modified farnesene polymer (C) in the rubber composition is from 2 to 10 parts by mass on the basis of 100 parts by mass of the silica (B).

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