Amway China Botanical Research Center

Wuxi, China

Amway China Botanical Research Center

Wuxi, China
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Liu J.-Q.,CAS Kunming Institute of Botany | Deng Y.-Y.,CAS Kunming Institute of Botany | Deng Y.-Y.,University of Chinese Academy of Sciences | Li T.-Z.,Amway China Botanical Research Center | And 4 more authors.
Molecules | Year: 2014

Acerola cherry is a world famous fruit which contains abundant antioxidants such as vitamin C, anthocyanins, flavonoids, and phenolics. However, studies concerning bioactivity components from aerial parts of acerola (Malpighia emarginata) are scarce. In view of this, we have examined the constituents of aerial parts of acerola, and three new tetranorditerpenes acerolanins A-C (1-3) with a rare 2H-benz[e]inden-2-one substructure were isolated. Their structures were determined on the basis of spectral studies and acerolanin C was confirmed by X-ray crystallographic analysis. Furthermore, three new compounds have been studied for their cytotoxic activity. © 2014 by the authors; licensee MDPI, Basel, Switzerland.


Liu J.-Q.,CAS Kunming Institute of Botany | Peng X.-R.,CAS Kunming Institute of Botany | Peng X.-R.,University of Chinese Academy of Sciences | Li X.-Y.,CAS Kunming Institute of Botany | And 8 more authors.
Organic Letters | Year: 2013

Three novel norfriedelanes, A-C (1-3), were isolated from the branches and roots of Malpighia emarginata. Their structures and absolute configurations were determined by 1D and 2D NMR techniques and X-ray crystallographic analysis. Norfriedelin A (possessing an α-oxo-β-lactone group) and norfriedelin B (with a keto-lactone group) showed acetylcholinesterase inhibitory effects with the IC50 values of 10.3 and 28.7 μM, respectively. © 2013 American Chemical Society.


PubMed | Amway China Botanical Research Center and CAS Kunming Institute of Botany
Type: Journal Article | Journal: Molecules (Basel, Switzerland) | Year: 2014

Acerola cherry is a world famous fruit which contains abundant antioxidants such as vitamin C, anthocyanins, flavonoids, and phenolics. However, studies concerning bioactivity components from aerial parts of acerola (Malpighia emarginata) are scarce. In view of this, we have examined the constituents of aerial parts of acerola, and three new tetranorditerpenes acerolanins A-C (1-3) with a rare 2H-benz[e]inden-2-one substructure were isolated. Their structures were determined on the basis of spectral studies and acerolanin C was confirmed by X-ray crystallographic analysis. Furthermore, three new compounds have been studied for their cytotoxic activity.

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