Heaney R.P.,Creighton University |
Heaney R.P.,Btr Inc. |
Recker R.R.,Creighton University |
Grote J.,AMES Inc. |
And 2 more authors.
Journal of Clinical Endocrinology and Metabolism | Year: 2011
Background: Current unitage for the calciferols suggests that equimolar quantities of vitamins D 2 (D2) and D 3 (D3) are biologically equivalent. Published studies yield mixed results. Objective: The aim of the study was to compare the potencies of D2 and D3. Design: The trial used a single-blind, randomized design in 33 healthy adults. Calciferols were dosed at 50,000 IU/wk for 12 wk. Principal outcome variables were area under the curve for incremental total 25-hydroxyvitamin D [25(OH)D] and change in calciferol content of sc fat. Results: Incremental mean (SD) 25(OH)D area under the curve at 12 wk was 1366 ng · d/ml (516) for the D2-treated group and 2136 (606) for the D3 (P < 0.001). Mean (SD) steady-state 25(OH)D increments showed similar differences: 24 ng/ml for D2 (10.3) and 45 ng/ml (16.2) for D3 (P < 0.001). Subcutaneous fat content of D2 rose by 50 μg/kg in the D2-treated group, and D3 content rose by 104 μg/kg in the D3-treated group. Total calciferol in fat rose by only 33 ng/kg in the D2-treated, whereas it rose by 104 μg/kg in the D3-treated group. Extrapolating to total body fat D3, storage amounted to just 17% of the administered dose. Conclusion: D3 is approximately 87% more potent in raising and maintaining serum 25(OH)D concentrations and produces 2- to 3-fold greater storage of vitamin D than does equimolar D2. For neither was there evidence of sequestration in fat, as had been postulated for doses in this range. Given its greater potency and lower cost, D3 should be the preferred treatment option when correcting vitamin D deficiency. Copyright © 2011 by The Endocrine Society.
Black W.C.,AMES Inc.
IEEE ISPLC 2010 - International Symposium on Power Line Communications and its Applications | Year: 2010
Distribution transformers are generally assumed to block high frequency power line carrier signals and to require bypass networks where signals must cross a transformer. In this work, however, we show experimentally that significant coupling occurs at some frequencies both across distribution transformers and between different transformer phases in various commercial transformers. This suggests that the transformers may pass noise and coupled RF signals between low and medium voltage power lines much more readily than predicted by simple models. It also suggests that frequency adaptive or spread-spectrum methods should be able to communicate across distribution transformers without bypass networks. Measured results are applied to a commercial simulator model suitable for use within large simulations. ©2010 IEEE.
Horst R.L.,AMES Inc.
Journal of Steroid Biochemistry and Molecular Biology | Year: 2010
Demand for circulating 25-hydroxyvitamin D [25(OH)D] measurements has exploded due to its relationship with many serious health problems. The present study was designed to investigate the validity of samples " spiked" with 25-hydroxyvitamin D2 [25(OH)D2] or 25-hydroxyvitamin D3 [25(OH)D3] to determine their analytical recovery by the DiaSorin LIAISON 25 OH Vitamin D Total Assay (DiaSorin Assay) and high-performance liquid chromatography (HPLC). 25(OH)D was measured in nine volunteers taking large daily doses of vitamin D2 for 2 weeks. Samples were obtained pre-supplementation and 1 week following vitamin D2. Pre-supplementation samples were used for exogenous recovery studies by adding 25(OH)D2 or 25(OH)D3. Endogenous 25(OH)D [25(OH)D2 plus 25(OH)D3] concentrations reported by the DiaSorin Assay or detected by HPLC were in excellent agreement. However, exogenously added 25(OH)D2 and 25(OH)D3 were under-recovered by the DiaSorin Assay. NIST vitamin D standards containing serum from another species (horse) or exogenous 25(OH)D2 were similarly affected when using the DiaSorin Assay. Exogenous 25(OH)D2, 25(OH)D3 or serum from other species added to human samples is inappropriate in determining the analytical recovery of vitamin D compounds when using the DiaSorin Assay. Only endogenous 25(OH)D2 and/or 25(OH)D3 contained in human blood samples should be utilized for this purpose. © 2010 Elsevier Ltd.
AMES Inc. | Date: 2015-02-10
A tablet computer includes a front display assembly and a rear housing that receives the front display assembly on a first side thereof. The tablet computer further includes a controller assembly that is coupled to a second side of the rear housing. The controller assembly has a controller housing and PCB assembly disposed in the controller housing. The PCB assembly has a microprocessor, a PCB, and a first I/O port connector. The controller housing has a first side wall with an aperture extending therethrough that is disposed adjacent to the first I/O port connector. The tablet computer further includes a first panel that is removably coupled to a portion of the second side of the rear housing such that the first panel and the first side wall define a first elongated aperture therebetween.
AMES Inc. | Date: 2014-08-11
An inlet conduit assembly for a hose reel assembly includes a clip assembly that is structured to be accessible from the outer side of the frame assembly. The clip assembly is structured to be operated without the use of tools. The clip assembly, essentially, prevents the inlet conduit assembly from being moved axially once installed. In this configuration, a user may quickly and easily actuate the clip assembly to release or engage the inlet conduit assembly. Thus, a user may quickly and easily remove the inlet conduit assembly.
AMES Inc. | Date: 2014-07-18
A head assembly for a rake is provided. The head assembly includes a base portion, a handle coupling, and a number of tines. Each tine includes an elongated body. Each tine body includes a first end, a flexure portion, an offset portion, and a distal second end. The tines includes a first set of tines and a second set of tines. A number of tine bodies in the first set of tines have an offset portion lateral cross-sectional aspect ratio that is greater than 1.0. A number of tine bodies in the second set of tines have an offset portion lateral cross-sectional aspect ratio that is less than 1.0.
AMES Inc. | Date: 2015-01-14
A watering assembly is provided. The watering assembly includes a reservoir body, a support assembly, a wicking assembly, and an inlet assembly. The reservoir body defines an enclosed space. The support assembly is structured to support soil. The support assembly is coupled to the reservoir body. The wicking assembly includes a number of wicking elements; the wicking elements are coupled to at least one of the reservoir body or support assembly. The wicking elements extend from the reservoir enclosed space to a location outside the reservoir enclosed space. The inlet assembly is coupled to the reservoir body and structured to provide fluid communication from a location outside the reservoir enclosed space to the reservoir enclosed space. When the reservoir body, the support assembly, the wicking assembly and the inlet assembly are assembled, the reservoir body, the support assembly, the wicking assembly and the inlet assembly form a contained watering assembly.
AMES Inc. | Date: 2016-02-02
AMES Inc. | Date: 2016-03-16
Agency: Department of Defense | Branch: Army | Program: SBIR | Phase: Phase I | Award Amount: 99.71K | Year: 2012
Current electric energy storage (EES) technologies cannot meet the requirement of both high power density and high energy density for portable electronics in general and gun fired munitions in particular. Advanced Materials and Energy Systems, Inc. (AMES) plans to resolve this issue by developing a novel High Density UltraCapacitor (HDUC). The innovation of the proposed HDUC is the use of ultrahigh permittivity dielectric composite being developed in AMES as the dielectric layers of multilayer capacitors. Thus the proposed HDUC will possess power density matching the capacitor, and energy density much higher than the state-of-the-art Li-ion batteries. The key issue of proposed work is to develop a dielectric polymer composite with Silicon based Amorphous Ceramic (SAC) as the filler. The composite will possess the ultrahigh dielectric permittivity, high dielectric strength, and high bulk resistivity. SAC is a new class of ceramics with a novel electric and dielectric property. Most recently, AMES has developed a SAC with dielectric permittivity many orders of magnitude higher than traditional dielectric materials. For this Phase I project, AMES will investigate the process to fabricate a SAC composite, characterize the properties of produced composite, also study the ability of energy absorption with high charging rate, perform the feasibility studies on the developing and prototyping this dielectric material for high power and energy density EES that would meet all military requirement.