American University in Cairo
Cairo, Egypt

The American University in Cairo is an independent, nonprofit, English language, liberal arts university located in Cairo, Egypt. The university offers American-styled learning programs at the undergraduate, graduate and professional levels, along with a continuing education program. The AUC student body represents over 100 countries. AUC's faculty members, adjunct teaching staff and visiting lecturers are internationally diverse and include academics, business professionals, diplomats, journalists, writers and others from the United States, Egypt and other countries. In 2014, the QS World University Rankings placed AUC 360th in the world, 3rd in Africa and 1st in Egypt, and named the School of Business as fourth best in Africa and the Middle East, and among the top 200 in the world. AUC holds institutional accreditation from the Middle States Commission on Higher Education and from Egypt's National Authority for Quality Assurance and Assessment of Education . Wikipedia.

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In general the present disclosure relates to Nylon 6/montmorillonite clay nanocomposites with enhanced mechanical properties that have been prepared primarily by solution compounding. A major challenge in producing the Nylon 6/montmorillonite clay nanocomposites is associated with the exfoliation and dispersion of the clay particles within the polymer matrix. This disclosure presents compositions and methods for obtaining highly or fully exfoliated nylon 6/montmorillonite nanocomposites, not only for organically modified clays with known compatibility with nylon 6 (Cloisite 30B), but also for clays with low/no compatibility with nylon 6 (Cloisite 15A and Na^(+)-MMT) through solution compounding.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INT-09-2015 | Award Amount: 2.50M | Year: 2016

The EU and Turkey face mounting challenges both in relation to one another and internationally. The EU is confronted with an economic crisis which is likely to make differentiation a growing phenomenon. Turkey faces polarisation between different political forces, the state and civil society. The neighbourhood is unravelling to the east and south and a power shift is under way at global level. This questions the regional roles of Turkey and the EU. Accordingly, FEUTURE a consortium of 13 experienced universities and think tanks from the EU, Turkey and the neighbourhood aims to: (1) map the dynamics of EU-Turkey relations as to underlying narratives and thematic drivers; (2) substantiate most likely future scenario(s) and assess its implications; (3) draw policy recommendations. FEUTURE provides excellence and pursues an ambitious, inspiring and innovative programme in a three-phased structure of elaboration, exploration and extrapolation. It applies an inter-temporal, interdisciplinary and international approach by analysing drivers within six thematic dimensions (politics, security, economics, energy, migration, identity) and across four levels of analysis (EU, Turkey, neighbourhood, global). Phases 1 and 2 culminate in an extrapolation phase in which FEUTURE integrates new knowledge and tests the implications of 3 ideal-type future scenarios for EU-Turkey relations: conflict, cooperation and convergence. We engage in a trans-disciplinary exchange within an elite survey and with the knowledge-user community from the four levels of analysis exploiting the full range of virtual and social media as well as traditional means. FEUTUREs work plan guarantees coherence of its research approach by streamlining work in one conceptual, one synthesis, two organisational and six thematic work packages. Joint WP meetings and three FEUTURE conferences assure intensive horizontal exchange. FEUTURE will achieve academic, practical and structural impact beyond the project.

The 2010-2011 youth-led wave of protests in the South and East Mediterranean, could be described as the coming on the scene of a new generation united by a shared experience of marginalisation and by new ways to protest and act. Important as this phenomenon could be for the future of the SEM, it still escapes the main frames of analysis utilised by academic research. Youth studies in the SEM, while producing important findings and insights, have failed so far to give a multi-dimensional and comprehensive understanding of the economic, political and social disadvantages faced by youth in the region and of the possible evolution of young peoples role in national or regional developments. This project aims at filling this important gap in our knowledge of the SEM by offering a comprehensive multi-level, interdisciplinary and gender-sensitive approach to the understanding of youth in the region. By combining the economic, political and socio-cultural spheres and a macro (policy/institutional), meso (organisational) and micro (individual) level analysis, POWER2YOUTH will explore the root causes and complex dynamics of youth exclusion, while investigating the factors fostering youth inclusion. Building on a conceptualisation of youth that gives prominence to youth as potential agents of change, the project starts out from the assumption that youth exclusion is the result of unequal power relations in society, in as much as effective youth inclusion can only be fostered by a bottom-up process of transformation of the systemic inequalities that lead to exclusion in the first place. From this premise comes the projects emphasis on the study of the potentially transformative impact of individual and collective youth agency searching for instances of empowerment leading to active youth participation in society and overall change. POWER2YOUTH will finally produce innovative and concrete policy recommendations.

Agency: European Commission | Branch: FP7 | Program: CP-FP-SICA | Phase: SSH.2013.4.1-2 | Award Amount: 3.12M | Year: 2014

Young people in the South and East Mediterranean area are enduring a multiple transitions. In addition to the political and socioeconomic transformations, there is the transition to adulthood from the famous tripartite division of the life cycle in preparation for professional life, working life and retirement. Other experiences of socio-economic transformation, as in East Europe, may give us learnt lessons to manage economic, political and social change. Today, there are no longer substantial differences separating the young people of west and east. Nevertheless, there are important differences in economic resources, education and social between two shores of the Mediterranean. In addition, the SEM young Europeans differ in cultural values and practices different from their counterparts in the north. Still, some processes linked to economic globalization and the precarious living conditions, labor and difficulties in individual empowerment, among others, suggest the emergence of a youth crime and its consolidation as a category of scientific analysis. This argument lets you put so research that supports integrating the European experiences in youth employment, political participation and gender equality, the youth situation in the context of transition and European double in similar scenarios on the south bank. To articulate such research dimensions the project will articulate the concept of triple transition, taking into account political transitions, socio-economic transitions, and invisible transition such as cultural trends and emotions related to youth and the insecurity about the future (resident generation)

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: SSH.2013.4.2-1 | Award Amount: 2.89M | Year: 2014

The project Media, Conflict and Democratisation investigates the role of traditional media and ICTs in conflicts that accompany and follow transitions to democracy. Our research focuses on three major arenas of contentious politics in emerging democracies: constitutional conflicts, accountability conflicts and election conflicts. We argue that the media cannot be sufficiently understood in isolation, but have to be seen as part of an arena of public contestation that is occupied by multiple actors, each of which thriving to dominate the interpretations and outcomes of ongoing conflicts. Thus, the project aims to investigate The way in which traditional media in emerging democracies portray conflicts and whether media coverage contributes to the polarisation or moderation of divisions The diffusion of conflict messages through new ICTs; The role perceptions, ethics and working practices of journalists in conflict situations; The communication behaviour of conflict parties governments, political leaders, civil society groups during conflicts and how communications heightens or ameliorates tensions The empirical research will be carried out in four emerging democracies: Serbia, Egypt, Kenya and South Africa. These countries were chosen because their political development is of great significance for the respective geographical region in which they are located. All four countries have experienced severe democratisation conflicts, but represent distinct contexts that help to understand how cultural, political and social factors shape the role of the media in democratisation conflicts. The project will closely work together with relevant stakeholders to develop recommendations for communication interventions that help to prevent conflicts and provide strategies for effective conflict management and conflict resolution. In particular, we will provide knowledge and skills as to how ICT tools can be used for effective communication management during conflicts

American University in Cairo | Date: 2015-05-20

Ligands that target the HCV-E2 binding site and methods of making and using them. A series of ligand binding sites on the large extracellular loop of the open conformation of CD81 have been identified. Several important sites were located in regions identified by mutational studies to be the site of E2 binding. Ligands that recognize these sites were identified. Linking together two or three ligands that bind with low or moderate affinities to different structurally unique sites on a target protein were used to generate small molecule ligand conjugates that exhibit very high affinities to their CD81 targets. Hybrid ligand molecules were also designed using fragment-based drug design methods to generate analogs of the ligands that bind more tightly to the protein than the parent compounds. Identification and design of groups of compounds that bind to CD81 for use as therapeutics for treating patients infected by Hepatitis C virus and other viruses that interact with CD81. By binding to CD81, these molecules can block 1) HCV and other viral entry into cells (infection), 2) inflammatory responses caused by HCV and other viral infections, and 3) the induction of HCV associated cancers.

American University in Cairo | Date: 2016-04-01

A multi-tier cloud-metering framework for metering cloud resources is presented. The proposed framework is capable of relating metering indicator of distributed resources contributing to the same application and located at different architectural levels. Metering data is collected from the front-end, the cloud nodes and VMs, and propagated through the middle-tier of the metering architecture to be processed and stored at the back-end. The design of the metering framework adopts a service-oriented architecture which allow the processing of cloud metering objects CMOs using service processing over open web transport protocol. To be able to build the middle and back-end tier, a SOA based on IPIoE and BOSML is presented which allow full consolidation of cloud resources achieving scalability and reducing the amount of wasted resources due to cloud resources de-fragmentation.

American University in Cairo | Date: 2015-01-16

A solar energy conversion niobium oxynitride microcone and a method of the synthesis and use of niobium oxynitride microcones are provided. The material is useful for solar energy conversion, optics, photocatalysis, electrochromics, sensors and biomedical applications. According to one embodiment, Nb205 microcones are formed by anodization of (1M NaF and 1 wt. % HF electrolyte 40 V 20 min), they were annealed in ammonia gas to allow their doping with nitrogen. Nitridation of the micro cones shifts the absorption edge from 450 nm for the oxide form to 777 nm for the oxynitride form.

American University in Cairo | Date: 2015-02-25

Hepatitis C Virus (HCV) infects 200 million individuals worldwide. Although several FDA approved drugs targeting the HCV serine protease and polymerase have shown promising results, there is a need for better drugs that are effective in treating a broader range of HCV genotypes and subtypes without being used in combination with interferon and/or ribavirin. Recently, the crystal structure of the core of the HCV E2 protein (E2c) has been determined, providing structural information that can now be used to target the E2 protein and develop drugs that disrupt the early stages of HCV infection by blocking E2s interaction with different host factors. By targeting sites containing conserved E2 amino acids in the CD81 binding site on HCV E2, one might also be able to develop drugs that block HCV infection in a genotype-independent manner. Using the E2c structure as a template, a structural model of the E2 protein core (residues 421-645) was developed that includes the three amino acid segments that are not present in the E2c crystal structure. Blind docking of a diverse library of 1715 small molecules to this model led to the identification of a set of 34 ligands predicted to bind near conserved amino acid residues involved in the HCV E2:CD81 interaction. Surface plasmon resonance was used to screen the ligand set for binding to recombinant E2 protein, and the best binders were subsequently tested to identify compounds that inhibit the infection of hepatocytes by HCV. One compound, 281816, blocked E2 binding to CD81 and inhibited hepatocyte infection by HCV genotypes 1a, 1b, 2a, 2b, 4a and 6a with IC50s ranging from 2.2 M to 4.6 M. Methods are described for preventing or treating HCV infection using small molecule inhibitors such as 281816 that target E2 and disrupt its interactions.

American University in Cairo | Date: 2015-02-12

A voltage regulator provides a regulated output voltage [108] from an input voltage [100] using control unit [106] to control a switched capacitor circuit [102] to periodically produce different output voltage levels Vx followed by a low pass filter [104] to give a regulated output voltage. Phase interleaving is used where the phases of different voltage levels are interleaved allowing for increased effective switching frequency and reduced switching losses. By controlling the average voltage on the flying capacitors, output voltage is regulated by modulating the resistance of the switches using a duty cycle. A control unit [106] is used to determine the operation region of the voltage regulator device and configure the switched capacitor circuit in each operation region. The controller contains a state machine that determines the switches configuration in each phase of a complete switching cycle.

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