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La Jolla, CA, United States

Patent
Ambrx Inc | Date: 2014-07-24

Modified bovine somatotropin polypeptides and uses thereof are provided.


Patent
Ambrx Inc | Date: 2014-04-02

Modified human growth hormone polypeptides and uses thereof are provided.


Patent
Ambrx Inc | Date: 2014-01-10

Modified relaxin polypeptides and their uses thereof are provided


Patent
Eli Lilly, Company and Ambrx Inc | Date: 2014-03-12

Modified canine leptin polypeptides and formulations and uses thereof, are provided including polyethylene glycol (PEG) modified canine leptin polypeptides, wherein the PEG moiety is covalently attached to a para-acetyl-phenylalanine (pAF) residue of the polypeptide, and related compositions and methods useful in treating companion animal obesity and other leptin-related disorders.


Patent
Ambrx Inc | Date: 2013-06-19

This invention relates to anti-CD70 antibodies and antibody drug conjugates comprising at least one non-naturally-encoded amino acid. Disclosed herein are CD70 antibodies with one or more non-naturally encoded amino acids and further disclosed are antibody drug conjugates wherein the CD70 antibodies of the invention are conjugated to one or more toxins. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, including therapeutic, diagnostic, and other biotechnology uses.

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