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Barnaul, Russia

The leading scientific university of the Altai region, Altai State Technical University is one of a number of universities of the city of Barnaul, Altai Krai, Russia. It is one of the largest institutions of higher learning in Russia.It was founded in February 1942 based on the Zaporozhye Engineering Institute. Altay State University was named after Ivan Polzunov who was the famous Barnaul inventor.The University offers full-time, part-time, extramural and distant training. On graduating students receive degrees of Bachelor and diplomas of specialist. Post-graduate courses are also offered.The facilities of the university include: 7 academic buildings, a complex of hostels, a large scientific library, computing center, publishing house, student clubs, a theater , a preventive clinic, as well as a skiing lodge, sports and rest camp by the river Ob. Wikipedia.

An innovative setup (fermenter) for studying biocatalytic conversions of the products from processing renewable cellulose-containing raw materials is developed and manufactured. The setup is tested in the enzymatic hydrolysis of the Russian miscanthus cellulose pulp. The final results (the dependence of the concentration of the reducing substances in the hydrolysate on the duration of enzymatic hydrolysis) completely reproduce those obtained earlier on laboratory equipment. Digestion of the obtained hydrolysate performed in parallel in the laboratory and in the fermenter also produces similar results. The setup for preparing enzymatic hydrolysates suitable for use as substrates in the production of bioethanol and bacterial cellulose and the possibility of scaling the volumes of the processes of biocatalytic transformation thus prove promising. © Pleiades Publishing, Ltd., 2014. © I.N. Pavlov, 2014. Source

Popov A.V.,Altai State Technical University
Crystallography Reports

Metallic lithium is used to demonstrate the possibilities of applying non-self-adjoint operators for quantitative description of orbital excitations of electrons in crystals. It is shown that, the nonequilibrium distribution function can be calculated when solving the spectral problem; therefore, the kinetic properties of a material can also be described with the unified band theory. © 2016, Pleiades Publishing, Inc. Source

Filimonov V.Y.,Altai State Technical University
Combustion Science and Technology

A new approach for consideration of the self-heating modes during monomolecular exothermic reaction has been proposed. The analysis of reactions in the phase plane heating rate and temperature enables detection of the variety of modes of the heating processes and allows consideration of two dimensional parametric model: Todes criterion and Semenov criterion. This gives the possibility of determining the characteristic regions in the corresponding parametric plane. The new thermokinetic parameters were introduced for the phase trajectories analysis. The characteristic values of parameters (and characteristic temperatures) can be determined at the intersection points of the phase trajectories and boundaries of regions. The analytical expression for the thermal explosion critical conditions, which includes Todes criterion, and the new thermokinetic parameters were obtained for the first-order reactions. The condition of applicability of the classical thermal explosion theory was proposed. It was shown that the classical theory of the thermal explosion is the partial case of the presented model. © 2014 Copyright Taylor and Francis Group, LLC. Source

Schepetkin I.A.,Montana State University | Khlebnikov A.I.,Altai State Technical University | Giovannoni M.P.,University of Florence | Kirpotina L.N.,Montana State University | And 2 more authors.
Current Medicinal Chemistry

Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) expressed on a variety of cell types. These receptors play an important role in the regulation of inflammatory reactions and sensing cellular damage. They have also been implicated in the pathogenesis of various diseases, including neurodegenerative diseases, cataract formation, and atherogenesis. Thus, FPR ligands, both agonists and antagonists, may represent novel therapeutics for modulating host defense and innate immunity. A variety of molecules have been identified as receptor subtype-selective and mixed FPR agonists with potential therapeutic value during last decade. This review describes our efforts along with recent advances in the identification, optimization, biological evaluation, and structure-activity relationship (SAR) analysis of small molecule non-peptide FPR agonists and antagonists, including chiral molecules. Questions regarding the interaction at the molecular level of benzimidazoles, pyrazolones, pyridazin-3(2H)-ones, N-phenylureas and other derivatives with FPR1 and FPR2 are discussed. Application of computational models for virtual screening and design of FPR ligands is also considered. © 2014 Bentham Science Publishers. Source

Golykh R.N.,Altai State Technical University
Journal of Physics: Conference Series

Progress of technology and medicine dictates the ever-increasing requirements (heat resistance, corrosion resistance, strength properties, impregnating ability, etc.) for non-Newtonian fluids and materials produced on their basis (epoxy resin, coating materials, liquid crystals, etc.). Materials with improved properties obtaining is possible by modification of their physicochemical structure. One of the most promising approaches to the restructuring of non-Newtonian fluids is cavitation generated by high-frequency acoustic vibrations. The efficiency of cavitation in non-Newtonian fluid is determined by dynamics of gaseous bubble. Today, bubble dynamics in isotropic non-Newtonian fluids, in which cavitation bubble shape remains spherical, is most full investigated, because the problem reduces to ordinary differential equation for spherical bubble radius. However, gaseous bubble in anisotropic fluids which are most wide kind of non-Newtonian fluids (due to orientation of macromolecules) deviates from spherical shape due to viscosity dependence on shear rate direction. Therefore, the paper presents the mathematical model of gaseous bubble dynamics in anisotropic non-Newtonian fluids. The model is based on general equations for anisotropic non-Newtonian fluid flow. The equations are solved by asymptotic decomposition of fluid flow parameters. It allowed evaluating bubble size and shape evolution depending on rheological properties of liquid and acoustic field characteristics. Source

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