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Patent
Alios BioPharma | Date: 2017-05-31

Described herein are methods for treating and/or ameliorating a paramyxovirus infection that includes the use of 3,5-(2-methylpropanoate)-4-C-(chloromethyl)-2-deoxy-2-fluoro-cytidine, or a pharmaceutically acceptable salt thereof, (Compound (A)), wherein Compound (A), or a pharmaceutically acceptable salt thereof, can provide 4-C-chloromethyl-2-deoxy-2-fluoro-5-(tetrahydrogen triphosphate)-cytidine, or pharmaceutically acceptable salt thereof (Compound (B)).


Patent
Alios BioPharma | Date: 2016-09-02

Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.


Patent
Alios BioPharma | Date: 2016-09-02

Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.


Patent
Alios BioPharma | Date: 2017-02-02

Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such as a Coronaviridae virus, a Togaviridae virus, a Hepeviridae virus and/or a Bunyaviridae virus infection with one or more nucleosides, nucleotides and nucleotide analogs.


Patent
Alios BioPharma | Date: 2017-02-08

Disclosed herein are nucleosides, nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a Filoviridae virus infection with one or more nucleosides and/or nucleotide analogs.


Patent
Alios BioPharma | Date: 2017-05-03

Disclosed herein are nucleosides, nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a Filoviridae virus infection with one or more nucleosides and/or nucleotide analogs.


Patent
Alios BioPharma | Date: 2017-05-03

Disclosed herein are methods of preparing a phosphoroamidate nucleotide anal which are useful in treating diseases and/or conditions such as viral infections.


Patent
Alios BioPharma | Date: 2016-06-13

Disclosed herein are cyclic nucleotide analogs, methods of synthesizing cyclic nucleotide analogs and methods of treating diseases and/or conditions such as viral infections, cancer, and/or parasitic diseases with cyclic nucleotide analogs.


Patent
Indiana University and Alios BioPharma | Date: 2016-03-02

Compositions and methods for the treatment of norovirus infection are disclosed.


Patent
Alios BioPharma | Date: 2016-02-24

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

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