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Patent
Alfresa Pharma Corporation and Maruho Hatsujyo Kogyo Co. | Date: 2012-08-29

A bone-tying cable tightening device is disclosed which makes itself unusable after having been used a predetermined number of times. The device includes a grip portion, a rod-like member, a knot-supporting means at the tip, and a cable-holding means to grip and hold the two arms of a cable, and is provided with a sliding block mounted around the rod-like member and connected to a pulling means, and an operation lever, wherein the cable-holding means includes (a) a longitudinal through groove defined in the upper part of the sliding block, (b) a locking recess which extends at the rear end the through groove, either transversing the cross section of the through groove or containing the cross section of the through groove, and whose width in the cross section thereof widens in the rearward direction, and (c) a backward biased locking member which is provided movably back and forth behind the locking recess on the upper side of the sliding block and so made that its forward movement is blocked when it fits in the locking recess, and wherein the device further includes a pull-releasing means which can be operated to release the one-way detent means for the pulling means, and a release locking means to lock the one-way detent means in a released state after the pull-releasing means has been operated a predetermined number of times.


Patent
Alfresa Pharma Corporation | Date: 2013-10-17

A microwave providing device is provided, which is capable of effectively extending the coagulation range of a treatment target tissue by setting the conditions for intermittently providing microwaves. An output controller controls a microwave generator based on a first efficiency of dielectric heating by microwaves with respect to a cumulative radiation period of microwaves radiated intermittently to a treatment target tissue S and a second efficiency of dielectric heating by microwaves with respect to a cumulative radiation period of microwaves radiated continuously to the treatment target tissue so that microwaves are intermittently radiated at least after a reference cumulative radiation period that is set in advance as a cumulative radiation period at which the first efficiency becomes larger than the second efficiency.


Patent
Kobe University, Alfresa Pharma Corporation and Kanai Juyo Kogyo Co. | Date: 2014-12-24

A radiotherapy spacer is disclosed that has both flexibility for allowing it to gently cover the organs of various shapes along their surfaces and pressure resistance for preventing itself from being crushed under the pressure between organs and thus enabling it to retain its own shape and continuously ensure the therapeutic space. The spacer comprises a fiber assembly formed of entangled biocompatible fibers, which may be bioabsorbable, such as nonwoven fabric, and is characterized in that the density of the fiber assembly is 0.05 g/cm^(3 )to 0.2 g/cm^(3).


It is an object of the present invention to provide a method for maintaining the reactivity of microparticles having a reactive substance bound thereto in a dispersion liquid of the microparticles over a long period of time by stabilizing the microparticles in the dispersion liquid. The invention provides a method for stabilizing microparticles having a reactive substance bound thereto, which includes the step of allowing a sulfur-containing amino acid or a derivative thereof to coexist in a dispersion liquid of the microparticles. As for the sulfur-containing amino acid, cysteine, cystine, and methionine are preferable. The method of the invention is particularly useful when a precipitation preventing substance, such as a polyanion, dextran, or the like, is allowed to coexist in the dispersion liquid.


Patent
Kobe University, Kanai Juyo Kogyo Co. and Alfresa Pharma Corporation | Date: 2012-09-12

Provided is a spacer for ionizing radiation therapy, which can be easily disposed in a living body, does not require abdominal surgery for removing the disposed spacer after radiation therapy, and can effectively separate a tissue to be treated from other tissues. The spacer for ionizing radiation therapy includes a fiber assembly obtained by three-dimensionally entangling a fibrous material formed of a biocompatible synthetic polymeric material. Specifically, the spacer has a thickness of 1 mm to 100 mm.


Patent
Alfresa Pharma Corporation | Date: 2012-05-02

A reagent kit for determining an analyte in a sample by agglutination includes a first reagent containing a first specific binding substance that is a substance that can specifically bind to the analyte; and a second reagent containing microparticles having a second specific binding substance bound thereto, the second specific binding substance being a monoclonal antibody against the first specific binding substance.


Patent
Alfresa Pharma Corporation and Tanaka Kikinzoku Kogyo K.K. | Date: 2016-04-27

The present invention provides an easy-to-use and high-sensitivity immunochromatography device for an RSV, the device using an antibody that binds specifically to F protein of the RSV in a determination region of a chromatography medium, a kit for an inspection by an immunochromatography method, and a method for detecting an RSV using these device and kit. The present invention relates to an immunochromatography device in which not only an antibody that binds specifically to F protein of an RSV but also an antibody that binds specifically to N protein of the RSV is solid-phased in a determination region of a chromatography medium, a kit for an inspection by an immunochromatography method, and a method for detecting an RSV using these device and kit.


Patent
Alfresa Pharma Corporation | Date: 2012-08-29

Disclosed is a flat cable formed by braiding ultra-high molecular weight polyethylene fibers, in which degree of the fibers close contact in a condition where no tensile force is applied is elevated compared with conventional ones. The cable is a flat cable formed by braiding ultra-high molecular weight polyethylene fibers, the area of whose cross section under a load of no tensile stress is not more than 110% of the cross section area under a load of a tensile stress of 22.7 N/mm^(2).


Patent
Kobe University, Alfresa Pharma Corporation and Kanai Juyo Kogyo Co. | Date: 2016-11-23

A radiotherapy spacer is disclosed that has both flexibility for allowing it to gently cover the organs of various shapes along their surfaces and pressure resistance for preventing itself from being crushed under the pressure between organs and thus enabling it to retain its own shape and continuously ensure the therapeutic space. The spacer comprises a fiber assembly formed of entangled biocompatible fibers, which may be bioabsorbable, such as nonwoven fabric, and is characterized in that the density of the fiber assembly is 0.05 g/cm^(3) to 0.2 g/cm^(3).


Patent
Alfresa Pharma Corporation and Tanaka Kikinzoku Kogyo K.K. | Date: 2014-06-20

The present invention provides an easy-to-use and higher-sensitivity immunochromatography device for an RSV, the device using an antibody that binds specifically to F protein of the RSV in a determination region of a chromatography medium, a test kit by an immunochromatography method, and a method for detecting an RSV using these device and kit. The present invention relates to an immunochromatography device in which not only an antibody that binds specifically to F protein of an RSV but also an antibody that binds specifically to N protein of the RSV is solid-phased in a determination region of a chromatography medium. The present invention also relates to a test kit by an immunochromatography method, and a method for detecting an RSV using these device and kit.

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