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Chūō-ku, Japan

Someya T.,Albion Co. | Nagasawa S.,Waseda University
ICIC Express Letters

This study aims to analyze factors necessary for stable growth oftraditional company. Based on Shoyeido's case, this study conducts analyses fromthe perspective of building customer experience, and also examinestechnological management. For this purpose, we investigated the product ofShoyeido and carried out an interview with President Masataka Rata. Shoyeido'scase seems to validate the following two hypotheses of this study. I:Traditional companies offer not only products but also added value called"customer experience" II: Traditional companies conduct technologymanagement based on core technologies. It is indicated that general companieswithout long histories have the potential for steady growth by incorporatingthese factors. ICIC International © 2010. Source

Sassa T.,Hokkaido University | Ohno Y.,Hokkaido University | Kashiwagi T.,Hokkaido University | Hirayama T.,Hokkaido University | And 9 more authors.
Molecular and Cellular Biology

The sphingolipid backbone ceramide (Cer) is a major component of lipid lamellae in the stratum corneum of epidermis and has a pivotal role in epidermal barrier formation. Unlike Cers in other tissues, Cers in epidermis contain extremely long fatty acids (FAs). Decreases in epidermal Cer levels, as well as changes in their FA chain lengths, cause several cutaneous disorders. However, the molecular mechanisms that produce such extremely long Cers and determine their chain lengths are poorly understood. We generated mice deficient in the Elovl1 gene, which encodes the FA elongase responsible for producing C20 to C28 FAs. Elovl1 knockout mice died shortly after birth due to epidermal barrier defects. The lipid lamellae in the stratum corneum were largely diminished in these mice. In the epidermis of the Elovl1-null mice, the levels of Cers with ≧C26 FAs were decreased, while those of Cers with ≦C24 FAs were increased. In contrast, the levels of C24 sphingomyelin were reduced, accompanied by an increase in C20 sphingomyelin levels. Two ceramide synthases, CerS2 and CerS3, expressed in an epidermal layer-specific manner, regulate Elovl1 to produce acyl coenzyme As with different chain lengths. Elovl1 is a key determinant of epidermal Cer chain length and is essential for permeability barrier formation. © 2013, American Society for Microbiology. All Rights Reserved. Source

Albion Co. | Date: 2015-08-07

Beauty serums; non-medicated skin care preparations.

Albion Co. and Albion Cosmetics Co. | Date: 2010-10-26

cosmetics and non-medicated skincare preparations.

Albion Co. | Date: 2015-08-07

Soaps for personal use; facial washes; skin cleansers.

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