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Kassar S.B.,Alagoas State University of Health Sciences | Melo A.M.C.,Federal University of Alagoas | Coutinho S.B.,Federal University of Pernambuco | Lima M.C.,Federal University of Pernambuco | Lira P.I.C.,Federal University of Pernambuco
Jornal de Pediatria | Year: 2013

Objective: To identify risk factors for neonatal mortality, focusing on factors related to assistance care during the prenatal period, childbirth, and maternal reproductive history. Methods: This was a case-control study conducted in Maceió, Northeastern Brazil. The sample consisted of 136 cases and 272 controls selected from official Brazilian databases. The cases consisted of all infants who died before 28 days of life, selected from the Mortality Information System, and the controls were survivors during this period, selected from the Information System on Live Births, by random drawing among children born on the same date of the case. Household interviews were conducted with mothers. Results: The logistic regression analysis identified the following as determining factors for death in the neonatal period: mothers with a history of previous children who died in the first year of life (OR = 3.08), hospitalization during pregnancy (OR = 2.48), inadequate prenatal care (OR = 2.49), lack of ultrasound examination during prenatal care (OR = 3.89), transfer of the newborn to another unit after birth (OR = 5.06), admittance of the newborn at the ICU (OR = 5.00), and low birth weight (OR = 2.57). Among the socioeconomic conditions, there was a greater chance for neonatal mortality in homes with fewer residents (OR = 1.73) and with no children younger than five years (OR = 10.10). Conclusion: Several factors that were associated with neonatal mortality in this study may be due to inadequate care during the prenatal period and childbirth, and inadequate newborn care, all of which can be modified. © 2013 Sociedade Brasileira de Pediatria.


De Medeiros S.K.F.,Alagoas State University of Health Sciences | De Carvalho W.B.,University of Sao Paulo | Soriano C.F.R.,Federal University of Alagoas
Jornal de Pediatria | Year: 2012

Objective: To investigate the use of nasal intermittent positive pressure ventilation (NIPPV) in level three neonatal intensive care units (NICU) in northeastern Brazil. Methods: This observational cross-sectional survey was conducted from March 2009 to January 2010 in all level three NICUs in northeastern Brazil that are registered in the Brazilian Registry of Health Establishments (Cadastro Nacional de Estabelecimentos de Saúde, CNES) of the Ministry of Health. Questionnaires about the use of NIPPV were sent to the NICU directors in each institution. Statistical analysis was conducted using the software Epi-Info 6.04 and double data entry. A chi-square test was used to compare variables, and the level of statistical significance was set at p ≤ 0.05. Results: This study identified 93 level three NICUs in northeastern Brazil registered in CNES, and 87% answered the study questionnaire. Most classified themselves as private institutions (30.7%); 98.7% used NIPPV; 92.8% adapted mechanical ventilators for NIPPV and used short binasal prongs as the interface (94.2%). Only 17.3% of the units had a protocol for the use of NIPPV. Mean positive inspiratory pressure and positive end-expiratory pressure were 20.0 cmH2O (standard deviation [SD]: 4.47) and 5.0 cmH2O (SD: 0.84). Conclusion: NICUs in northeastern Brazil use nasal intermittent positive pressure ventilation, but indications and ventilation settings are not the same in the different institutions. Copyright © by Sociedade Brasileira de Pediatria.


Riveros A.,Viña del Mar University | Riveros A.,University of the Frontier | Olave E.,University of the Frontier | Sousa-Rodrigues C.,Alagoas State University of Health Sciences
International Journal of Morphology | Year: 2015

Between the syndromes of nerve compression in the forearm, due to the presence of the tendinous arches related to the nerves that pass between its muscle layers, is the anterior interosseous nerve (AIN). The presence of muscular variations can generate arches that cause nerve compression. The aim of our study was to establish the incidence and morphology of the accessory head of flexor pollicis longus muscle (AFPLm) and its relationship with AIN or its branches. Thirty forearms of formalized corpses of adult Brazilians were used. The selected landmark for measurements was the medial epicondyle of the humerus (MEH). It was noted that three upper limbs presented the AFPLm (10%), originated from the MEH to end inserted into the tendon of the flexor pollicis longus muscle. The AFPLm showed fusiform appearance, which had a tendon that formed an arch with the flexor pollicis longus muscle. In one case, this arch was associated with the passage of AIN. In the other two, this arch was related to motor branches originating from the AIN. The diagnosis of nerve compression syndromes should consider the presence of AFLPm, which potentially can be related to the course of the AIN or its branches. © 2015, Universidad de la Frontera. All rights reserved.


Guimaraes J.A.T.L.,Alagoas State University of Health Sciences | Guimaraes J.A.T.L.,Instituto Medico Legal Of Maceio | Villela W.V.,University of Sao Paulo
Cadernos de Saude Publica | Year: 2011

The purpose of this study was to characterize cases of violence against children and adolescents examined at the Forensic Medicine Institute in Maceió, Alagoas State, Brazil. Three hundred and three cases from September, 2008 to March, 2009, were analyzed. Victims were interviewed and data were collected on the type of violence, victim's gender, age, schooling, and economic class, maternal schooling, characteristics of the aggressor and person reporting the case, location, and repeat offenses. Violence against children and adolescents in this sample was concentrated in lower income groups, and girls were victimized more frequently than boys. Most perpetrators were non-relatives, but known to the family. Sexual abuse was more common among younger children, while physical assault was more common against adolescents. The victim's home was the most frequent site of the violence. Further studies are needed to determine whether violence in other socioeconomic groups and against males actually does not occur, or whether it simply is not reported to the Forensic Medicine Institute and thus remains invisible.


Quini C.C.,São Paulo State University | Americo M.F.,Federal University of Mato Grosso | Cora L.A.,Alagoas State University of Health Sciences | Calabresi M.F.F.,São Paulo State University | And 3 more authors.
Journal of Biological Engineering | Year: 2012

AC Biosusceptometry (ACB) was previously employed towards recording gastrointestinal motility. Our data show a reliable and successful evaluation of gastrointestinal transit of liquid and solid meals in rats, considering the methods scarcity and number of experiments needed to endorsement of drugs and medicinal plants. ACB permits real time and simultaneous experiments using the same animal, preserving the physiological conditions employing both meals with simplicity and accuracy. © 2012 Quini et al.; licensee BioMed Central Ltd.


Marques R.G.,São Paulo State University | Americo M.F.,Federal University of Mato Grosso | Spadella C.T.,São Paulo State University | Cora L.A.,Alagoas State University of Health Sciences | And 2 more authors.
Physiological Measurement | Year: 2014

The relationship between time-courses of mechanical and electrical events in longstanding diabetes was investigated in rats. Magnetic markers and electrodes were surgically implanted in the gastric serosa of male rats. Simultaneous recordings were obtained by AC biosusceptometry, electromyography and electrogastrography one, three and six months after injections of saline (control) or alloxan (diabetic). Frequency and amplitude of contraction, abnormal rhythmic index and half-bandwidth were obtained (ANOVA P < 0.05). Antral hypomotility and gastric motility instability were observed in the signal waveform of diabetic rats at the three time points of study. The mean frequency (4.4 ± 0.4 cpm) was strictly similar, but the mechanical and electrical correlation was lowest for diabetics groups. Decreases in mechanical amplitude were observed for all diabetic groups compared with control; also the ranges of frequency were much wider in diabetes. The half-bandwidth increased since the first month in mechanical recordings and only after the third month in electrical. In diabetic animals, about 40% of gastric activity was abnormal (against 12% in control) and may reach 60% in the sixth month of mechanical recordings. The multi-instrumental approach showed a more substantial deterioration in mechanical activity and created an integrative view of gastric motility for longstanding diabetic model. © 2014 Institute of Physics and Engineering in Medicine.


Teles F.,Alagoas State University of Health Sciences | de Azevedo V.F.D.,Alagoas State University of Health Sciences | de Miranda C.T.,Federal University of Alagoas | de Melo Miranda M.P.,Federal University of Alagoas | And 2 more authors.
Clinics | Year: 2014

OBJECTIVE: Depression is the most important neuropsychiatric complication in chronic kidney disease because it reduces quality of life and increases mortality. Evidence demonstrating the association between dialysis shift and depression is lacking; thus, obtaining such evidence was the main objective of this study. METHOD: This cross-sectional study included patients attending a hemodialysis program. Depression was diagnosed using Beck's Depression Inventory. Excessive daytime sleepiness was evaluated using the Epworth Sleepiness Scale. RESULTS: A total of 96 patients were enrolled (55 males, age 48¡14 years). Depression and excessive daytime sleepiness were observed in 42.7% and 49% of the patients, respectively. When comparing variables among the three dialysis shifts, there were no differences in age, dialysis vintage, employment status, excessive daytime sleepiness, hemoglobin, phosphorus levels, or albumin levels. Patients in the morning shift were more likely to live in rural areas (p,0.0001), although patients in rural areas did not have a higher prevalence of depression (p = 0.30). Patients with depression were more likely to be dialyzed during the morning shift (p = 0.008). Independent risk factors for depression were age (p,0.03), lower levels of hemoglobin (p,0.01) and phosphorus (p,0.01), and dialysis during the morning shift (p = 0.0009). The hospitalization risk of depressive patients was 4.5 times higher than that of nondepressive patients (p,0.008). CONCLUSION: These data suggest that depression is associated with dialysis shift, higher levels of phosphorus, and lower levels of hemoglobin. The results highlight the need for randomized trials to determine whether this association occurs by chance or whether circadian rhythm disorders may play a role. © 2014 CLINICS.


Teixeira M.C.,Alagoas State University of Health Sciences
Transplantation proceedings | Year: 2012

Gastrointestinal (GI) complications are common after renal transplantation, mainly owing to immunosuppressive therapy. Assessment of GI transit time can facilitate rational management of these disorders. We evaluate the GI transit parameters in renal transplant recipients taking tacrolimus, azathioprine, and prednisone with the use of the alternate current biosusceptometry (ACB) technique and compared them with healthy volunteers. Ten renal transplant recipients and 10 healthy volunteers were enrolled in this study. After an overnight fast, patients and volunteers ingested a standard meal containing magnetic markers. The biomagnetic monitoring was performed at 10-minute intervals for at least 8 hours to obtain gastric emptying as well as the colonic arrival time-intensity curves. Mean gastric emptying time (MGET), mean colon arrival time (MCAT), and mean small intestinal transit time (MSITT) were quantified and compared between control and patient groups with results expressed as mean ± SD. The MGET measured by the ACB technique was 48 ± 31 minutes and 197 ± 50 minutes for patients and healthy subjects, respectively. MSITT and MCAT values calculated for patients versus volunteers were 171 ± 71 minutes versus 197 ± 71 minutes and 219 ± 83 minutes versus 373 ± 52 minutes, respectively. Renal transplant recipients showed significantly faster; gastric emptying and colon arrival times (P < .001) compared with normal volunteers; however, small intestinal transit time was not significantly different (P = .44). In stable renal transplant recipients, the GI transit parameters were significantly faster than in normal healthy volunteers. ACB sensors are versatile technologies that can be used for clinical research, because they offer an excellent opportunity to evaluate GI transit in a noninvasive manner without the use of ionizing radiation. Copyright © 2012 Elsevier Inc. All rights reserved.


de Oliveira C.M.G.,Alagoas State University of Health Sciences | Lanza F.C.,Federal University of São Paulo | Sole D.,Federal University of São Paulo
Jornal Brasileiro de Pneumologia | Year: 2012

Objective: To compare children/adolescents with mild or moderate asthma and healthy subjects in terms of respiratory muscle strength, correlating it with spirometric variables in the former group. Methods: This was a cross-sectional study involving individuals 6-16 years of age and clinically diagnosed with mild/moderate asthma, together with a group of healthy, age- and gender-matched subjects. We determined spirometric values, as well as MIP and MEP, and we selected three reproducible measurements (variation < 10%). Results: We evaluated 75 patients with asthma and 90 controls. The mean age was 10.0 ± 2.6 years. There were no statistically significant differences between the controls and the asthma group regarding MIP (-89.7 ± 26.7 cmH2O vs. -92.2 ± 26.3 cmH2O; p = 0.541) or MEP (79.2 ± 22.9 cmH2O vs. 86.4 ± 24.0 cmH2O; p = 0.256). The groups were subdivided by age (children and adolescents: 6-12 and 13-16 years of age, respectively). Within the asthma group, there was a significant difference between the child and adolescent subgroups in terms of MEP (74.1 ± 24.1 cmH2O vs. 92.1 ± 21.9 cmH2O; p < 0.001) but not MIP (p = 0.285). Within the control group, there were significant differences between the child and adolescent subgroups in terms of MIP (-79.1 ± 17.7 cmH2O vs. -100.9 ± 28.1 cmH2O; p < 0.001) and MEP (73.9 ± 18.7 cmH2O vs. 90.9 ± 28.1cmH2O; p < 0.001). In the asthma group, spirometric variables did not correlate with MIP or MEP. Conclusions: In our sample, asthma was found to have no significant effect on respiratory muscle strength.


Da Silva J.P.L.,Alagoas State University of Health Sciences | Teles F.,Alagoas State University of Health Sciences
Revista Brasileira de Anestesiologia | Year: 2012

Background and objectives:: Early recognition of abdominal compartment syndrome (ACS) is essential, as delay in the diagnosis may induce a negative impact on prognosis. However, there are some evidences suggesting a low level of knowledge concerning ACS in intensive care units (ICU). The aim of this study was to evaluate the intensivist's knowledge on ACS. Methods: We distributed 49 questionnaires, with 13 multiple choice questions, in seven ICU, which addressed the concept, diagnosis, and management of ACS. Results: Thirty-two questionnaires were answered. Forty-seven percent of respondents have more than 16 years of medical practice and spend more than 50% of their time in ICU. Although 75% reported having knowledge of ACS' concept, only 34% had measured intra-abdominal pressure (IAP). The most used method for measurements was urinary catheterization (91%). For 37%, the frequency of measurement should be based on clinical data rather than IAP values. Regarding the indication to IAP monitoring, the choices were performing the measurement after urgent laparotomy (25%), in massive volemic replacement (18%) and in other hazardous conditions (57%). The lack of information about measurement techniques was the main reason for not measuring IAP. Most respondents (90%) suggested the measurement of IAP as a routine in ICU. Conclusion: Intensivists' knowledge on ACS was low, as most were not able to measure, interpret the results and recognize important risk factors for IAP. These data demonstrate that educational efforts concerning ACS are necessary in order to standardize the measurement of IAP in populations at risk, aiming at a better outcome in critically ill patients. © 2012 Elsevier Editora Ltda.

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