Hou H.J.M.,Alabama State University
Materials | Year: 2011
In nature, the water-splitting reaction via photosynthesis driven by sunlight in plants, algae, and cyanobacteria stores the vast solar energy and provides vital oxygen to life on earth. The recent advances in elucidating the structures and functions of natural photosynthesis has provided firm framework and solid foundation in applying the knowledge to transform the carbon-based energy to renewable solar energy into our energy systems. In this review, inspired by photosynthesis robust photo water-splitting systems using manganese-containing materials including Mn-terpy dimer/titanium oxide, Mn-oxo tetramer/Nafion, and Mn-terpy oligomer/tungsten oxide, in solar fuel production are summarized and evaluated. Potential problems and future endeavors are also discussed. © 2011 by the authors. Source
Agency: NSF | Branch: Standard Grant | Program: | Phase: RSCH EXPER FOR UNDERGRAD SITES | Award Amount: 336.63K | Year: 2014
This REU Site award to Alabama State University, located in Montgomery, AL, will support the training of 10 students for 10 weeks during the summers of 2014 - 2016. The focus of this program is to provide research experiences in the multidisciplinary fields of nanotechnology and biotechnology. Faculty from biological sciences, chemistry, physical sciences and other related disciplines will be serving as mentors for the program. All research projects will be based on novel concepts of design and development of new nanomaterials for biological applications. Students will participate in a full-time closely mentored lab research project along with seminars and various professional development workshops, such as the responsible conduct of research, professional communication skills, career opportunities in academia and industry, and the graduate school application process. Students will present their findings at both a poster session and research symposium during the final weeks of the program. Students will also take field trips to encourage interactions with the faculty and students at Alabama State University. Housing, a stipend, and meal and travel allowances will be provided. Students will be selected based on their interest in research, academic record, and phone interviews with potential faculty mentors.
The REU program is intended to encourage students to pursue a career in STEM fields. Students will learn how research is conducted and many will present the results of their work at scientific conferences. Members of underrepresented minority groups and from colleges with limited research opportunities are especially encouraged to apply.
Program evaluation will use both internal evaluations and the BIO REU common assessment tool. Students are required to be tracked after the program and must respond to an automatic email sent via the NSF reporting system. More information is available by visiting http://www.alasu.edu/REU , or by contacting the PI (Dr. Komal Vig at email@example.com) or the co-PI (Dr. Shree R. Singh at firstname.lastname@example.org).
Agency: NSF | Branch: Standard Grant | Program: | Phase: | Award Amount: 450.00K | Year: 2015
PI: Dean, Derrick R.
Proposal Number: 1510479
The human anterior cruciate ligament (ACL) is ruptured over 200,000 times per year (or an incidence of 1 in 3000) in the United States, resulting in over $1 billion of medical expenses. The gold standard for surgical repair is the patellar tendon autograft, but this treatment is far from optimal due to lengthy recovery time, potential for developing arthritis, associated donor site morbidity, and degenerative joint disease. These limitations have prompted the need for a tissue engineered solution. This study proposes to use a multidisciplinary approach to provide a fundamental understanding of the design and fabrication of a scaffold (a temporary structure made of a biodegradable polymer that facilitates the growth of cells and tissue) that mimics and facilitates the development of the four tissue types found in the ACL structure. Students will be involved in the research, and several courses will benefit from the knowledge generated by this project.
The human anterior cruciate ligament (ACL) is ruptured over 200,000 times per year (or an incidence of 1 in 3000) in the United States, resulting in over $1 billion of medical expenses. The conventional surgical repair involves autografting the patellar tendon autograft, however shortcomings of this approach include long recovery time, potential for developing arthritis, associated donor site morbidity, and degenerative joint disease. These limitations underscore the need for a tissue engineered solution. This study proposes to use a multidisciplinary approach which provides a fundamental understanding of the evolution of a hierarchical, spatially organized 2-dimensional biomimetic scaffold designed to facilitate the development of the four tissue types found in a ligament-to-bone interface. The objectives of this study are: To utilize inkjet printing to prepare hierarchical, spatially organized structures that can be used for bone-ligament interfaces; to characterize the morphology, composition, mechanical behavior and immunochemistry across the bone-to-ligament interface; and to understand the material-cell interactions across the gradient structure. The fundamental knowledge gained from this study will significantly impact the engineering of bone-ligament interfaces and other applications where gradient structures are present. Program resources will be leveraged with the existing REU program at Alabama State University and the NSF/Louis Stokes Alliance for Minority Participation program (LSAMP), to maximize the involvement of undergraduate students from underrepresented groups. Several courses will benefit from knowledge generated from the research, and students involved will have opportunities to present their research at national and regional conferences.
University of South Florida and Alabama State University | Date: 2011-01-24
The subject invention concerns materials and methods for detecting nucleic acid sequences. One aspect of the invention concerns a silicon-based biochip comprising nucleic acid immobilized thereon. In one embodiment, the silicon comprises microcavities. The nucleic acid to be assayed for the presence of one or more target nucleic acid sequences is immobilized on the silicon. A nucleic acid, such as an oligonucleotide probe, having a sequence substantially complementary to the target nucleic acid sequence can be used to detect the immobilized nucleic acid on the silicon. If the nucleic acid used for detection hybridizes with a target nucleic acid sequence, the hybridized sequences can be detected directly or indirectly. In an exemplified embodiment, the oligonucleotide probe can be labeled with a detectable label, for example, a fluorescent molecule. The subject invention also concerns methods for detecting a target nucleic acid using a silicon-based biochip of the invention.
Agency: NSF | Branch: Standard Grant | Program: | Phase: BIO Innovation Activities | Award Amount: 49.95K | Year: 2014
This project seeks to create an RCN-UBE network for the purpose of providing faculty development activities at several historically black colleges and universities (HBCUs) in Alabama. The HBCU-Alabama Biosciences Network (HBCU-ALBN) will be a community of biologists and life scientists from all ranks, diverse experiences, pedagogical approaches and scientific training who will be willing to adopt and explore recommended curriculum changes in undergraduate science education that are much needed in the HBCU system.
Virtual and in-person planning meetings by the Steering Committee will proceed a workshop planned for the summer of 2014 at Alabama State University. Network activities will provide a forum to exchange examples of reforms that are underway and will challenge other faculty to incorporate active learning approaches in their classes to better engage students. For example, faculty will consider using case studies to demonstrate the everyday relevance of what students learn in life science courses, encourage cooperative learning among students, and explore the use of new technologies in the classroom.
The broader impacts of the project lie in forming a network of faculty at HBCUs who want to adopt student-centered approaches in the classroom to better engage students. Courses for both majors and non-majors will be the focus of network activities to improve biological literacy of all students and retention of students interested in biology. Currently there is no central association of life science faculty at HBCUs in Alabama for them to share resources and information to improve undergraduate biology education. This RCN-UBE network plans to form such a network that could serve as a model for other HBCUs and community colleges in other states.
This project is funded jointly by the Directorate for Biological Sciences and the Directorate of Education and Human Resources, Division of Undergraduate Education in support of efforts to address the challenges posed in Vision and Change in Undergraduate Education: A Call to Action http://visionandchange.org/finalreport/