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Rahoud S.A.,University of Gezira | Mergani A.,University of Gezira | Khamis A.H.,Sudan University of Science and Technology | Saeed O.K.,University of Gezira | And 3 more authors.
FEMS Immunology and Medical Microbiology | Year: 2010

An association study of a cohort of 177 Sudanese patients infected with Schistosoma mansoni [82 (46%) males and 95 (54%) females] was conducted to evaluate the factors controlling the regression of liver fibrosis 39 months after treatment with praziquantel using ultrasound evaluation. Periportal fibrosis (PPF) was regressed in 63 (35.6%) patients, while the disease progressed to higher grades in 24 (13.6%) patients. The grade of PPF did not change in 90 (50.8%) patients. The mean values of portal vein diameter, splenic vein diameter and index liver size in subjects in whom PPF regressed after treatment were significantly lower than in subjects in whom the disease was progressed (P<0.0001, P=0.031 and P=0.003, respectively). The progression of hepatic fibrosis in males (15, 8.5%) was greater than that in females (9, 5.1%). Patients with regression or progression phenotypes tend to cluster in certain families. Our study indicated that regression, progression and stabilization of PPF after praziquantel therapy is controlled by gender, age, grade of fibrosis and possibly inherited factors. © 2009 Federation of European Microbiological Societies. Source


Mohamedzein Y.E.-A.,Sultan Qaboos University | Nour Eldaim F.A.E.,Al Zaiem Al Azhari University | Abdelwahab A.B.,University of Khartoum
International Journal of Geotechnical Engineering | Year: 2013

This paper presents the results of laboratory model tests conducted to study the behavior of laterally loaded piles installed in plastic clay. The effects of different factors such as pile dimensions, pile material and method of installation were studied. The pile response is presented in terms of load-deflection curves, bending moment distribution, and the p-y curves. The load-deflection curves are generally non-linear specially for large length/diameter (L/d) ratios and large diameters. The ultimate lateral pile capacity increases with the increase in L/d ratio and the pile diameter. The maximum bending moment increases with the increase in L/d ratio and the pile diameter. The maximum bending moment occurs at a depth varying from 0·13L to 0·32L. The bending stresses at the ultimate load are much less than the yielding stress of steel and the flexural strength of concrete. This implies that the deflection controls the design of laterally loaded piles in plastic clays. The experimental p-y curves are different from the existing p-y curves for piles with small diameters and are approximately similar to the existing p-y curves for piles with larger diameters. The bored method of installation gives greater ultimate soil resistance than the preinstalled method for both concrete and steel piles. Overall this study showed that the laboratory model tests with relatively large diameter (>30 mm) can be used to give insight into the performance of laterally loaded piles installed in plastic clays. © 2013 W. S. Maney & Son Ltd Source


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