Al Jabal Al Gharbi University
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Fayrouz I.N.E.,Menoufia University | Farida N.,General Motors | Irshad A.H.,Al Jabal Al Gharbi University
Journal of Forensic and Legal Medicine | Year: 2012

Fingerprint is one of the oldest, reliable and mature biometric technologies and is considered one of the best, cheapest and legitimate proofs of identification. A correlation between physical characteristics like fingerprints and blood group was demonstrated in previous studies. This study was carried out in 2010 on 305 Libyan medical students of Al-Jabal Al-Gharbi, University, Zawia, Libya and were selected randomly having different ABO blood groups, with the objective to a) Study distribution of fingerprint pattern among the subjects having different ABO and Rh blood group b) Correlate any relation between their characters and blood group. The data from the study showed that male: female ratio was 1.2:1. Majority of subjects (48.9%) in this study were of blood group O followed by blood group A (33.1%), B (12.8%) and AB (5.2%). Rh-positive cases constitute about 87.2% of all studied cases. The general distribution of pattern of finger showed high frequency of Loops registering 50.5%; followed by whorls (35.1%) and arches (14.4%). In Rh+ve cases of blood group A and O loops incidences were the highest (52% and 54.3% respectively) then whorls (33.4% and 30.6% respectively), while in blood group B whorls were predominance in both Rh+ve and Rh-ve cases. In all blood groups there were high frequency of loops in thumb, index and little fingers. © 2011 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Ali J.A.M.,University of Glasgow | Ali J.A.M.,Al Jabal Al Gharbi University | Creek D.J.,University of Glasgow | Creek D.J.,University of Melbourne | And 5 more authors.
Molecular Pharmacology | Year: 2013

African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host. However, uptake of pyrimidines in bloodstream form trypanosomes has not been investigated, making it difficult to judge the relative importance of salvage and synthesis or to design a pyrimidine-based chemotherapy. Detailed characterization of pyrimidine transport activities in bloodstream form Trypano-soma brucei brucei found that these cells express a highaffinity uracil transporter (designated TbU3) that is clearly distinct from the procyclic pyrimidine transporters. This transporter had low affinity for uridine and 2′deoxyuridine and was the sole pyrimidine transporter expressed in these cells. In addition, thymidine was taken up inefficiently through a P1-type nucleoside transporter. Of importance, the anticancer drug 5-fluorouracil was an excellent substrate for TbU3, and several 5-fluoropyrimidine analogs were investigated for uptake and trypanocidal activity; 5F-orotic acid, 5F-2′deoxyuridine displayed activity in the low micromolar range. The metabolism and mode of action of these analogs was determined using metabolomic assessments of T. brucei clonal lines adapted to high levels of these pyrimidine analogs, and of the sensitive parental strains. The analysis showed that 5-fluorouracil is incorporated into a large number of metabolites but likely exerts toxicity through incorporation into RNA. 5F-2′dUrd and 5F-2′dCtd are not incorporated into nucleic acids but act as prodrugs by inhibiting thymidylate synthase as 5F-dUMP. We present the most complete model of pyrimidine salvage in T. brucei to date, supported by genome-wide profiling of the predicted pyrimidine biosynthesis and conversion enzymes. Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics.

Abdellatif M.Z.M.,Minia University | El-Mabrouk K.,Al Jabal Al Gharbi University | Ewis A.A.,Minia University
Korean Journal of Parasitology | Year: 2013

Cutaneous leishmaniasis (CL) is an endemic parasitic infection in the Mediterranean region, including Libya and its Al-jabal Al-gharbi province. We aimed at studying the occupational relevance as well as other epidemiological aspects of CL. We investigated 140 CL cases who attended at Gharyan outpatient polyclinic during a period of 6 months in 2009. CL infection was clinically diagnosed and confrmed by demonstration of Leishmania parasites on smears from lesions. Our fndings showed that males were more affected than females (P= 0.04), and people above 10-years were more affected than younger ones (P=0.0001). A significant percent of CL cases belonged to Al-Kawasem subprovince (P=0.0001). Farm-related activities were the most frequent occupations among CL cases (P= 0.04). In addition to farm workers, housewives and students are at risk groups since they are engaged at farm activities. Moreover, those who have occupations that require staying outdoors for a part of night, e.g., policemen, are also at risk. Compared to children, adult CL patients had multiple lesions (P= 0.001) that were more prevalent in their upper and lower extremities than the face (P=0.0001). We conclude that CL is a major health problem in Al-jabal Al-gharbi province of Libya. The presence of rodents and sandfies makes it a suitable environment for Leishmania to spread in an endemic epidemiological pattern. Being engaged in farming activities or outdoor occupations increases the risk of infection. Various clinical patterns of CL suggest the presence of more than 1 species of Leishmania at Al-jabal Al-gharbi province. We propose that the 2 species responsible for CL in this area are L. major and L. tropica. Further investigations to identify the leishmanial species responsible for CL at Al-jabal Al-gharbi together with adoption of preventive and control programs are needed. © 2013, Korean Society for Parasitology and Tropical Medicine.

Challa B.R.,Siddharth Institute of Pharmacy | Awen B.Z.,Al Jabal Al Gharbi University | Chandu B.R.,Al Jabal Al Gharbi University | Rihanaparveen S.,Jawaharlal Nehru Technological University Anantapur
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | Year: 2011

Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) was used for a quantitative estimation of entecavir (EV) in human plasma using lamivudine (LM) as internal standard (IS). The method herein described is simple, sensitive, and specific. Chromatographic separation was performed on XBridge-C18, 4.6. mm × 50 mm, 5-μm column with an isocratic mobile phase composed of 10 mM ammonium hydrogen carbonate (pH 10.5):methanol (85:15 v/v), pumped at 0.3. ml/min. EV and LM were detected using proton adducts at m/. z 278.1 → 152.1 and 230.2 → 112.0 in multiple reaction monitoring (MRM) positive mode. Solid phase extraction method was employed in the extraction of EV and LM from the biological matrix. This method was validated over a linear concentration range of 50.0-20000.0. pg/ml with a correlation coefficient (r) ≥0.9983. Intra and inter-day precision of EV was found within the range of 1.2-4.2 for EV and 4.4-4.5 for LM. EV was stable throughout three freeze/thaw cycles, bench top and postoperative studies. This method was successfully used in the analysis of plasma samples following oral administration of EV (0.5. mg) in 26 healthy human volunteers. © 2011 Elsevier B.V.

El-Menyawy E.M.,National Research Center of Egypt | Zedan I.T.,HIGH-TECH | Nawar H.H.,Al Jabal Al Gharbi University
Physica B: Condensed Matter | Year: 2014

The electrical and dielectric properties of the synthesized 2-(antipyrin-4-ylhydrazono)-2-(4-nitrophenyl)acetonitrile (AHNA) have been studied. The direct and alternating current (DC and AC) conductivities and complex dielectric constant were investigated in temperature range 303-403 K. The AC conductivity and dielectric properties of AHNA were investigated over frequency range 100 Hz-5 MHz. From DC and AC measurements, electrical conduction is found to be a thermally activated process. The frequency-dependent AC conductivity obeys Jonscher's universal power law in which the frequency exponent decreases with increasing temperature. The correlated barrier hopping (CBH) is the predominant model for describing the charge carrier transport in which the electrical parameters are evaluated. The activation energy is found to decrease with increasing frequency. The behaviors of dielectric and dielectric loss are discussed in terms of a polarization mechanism. The dielectric loss shows frequency power law from which the maximum barrier height is determined as 0.19 eV in terms of the Guintini model. © 2013 Elsevier B.V.

Vannucci L.,Institute of Microbiology | Vannucci L.,Academy of Sciences of the Czech Republic | Krizan J.,Institute of Microbiology | Sima P.,Institute of Microbiology | And 5 more authors.
International Journal of Oncology | Year: 2013

New foods and natural biological modulators have recently become of scientific interest in the investigation of the value of traditional medical therapeutics. Glucans have an important part in this renewed interest. These fungal wall components are claimed to be useful for various medical purposes and they are obtained from medicinal mushrooms commonly used in traditional Oriental medicine. The immunotherapeutic properties of fungi extracts have been reported, including the enhancement of anticancer immunity responses. These properties are principally related to the stimulation of cells of the innate immune system. The discovery of specific receptors for glucans on dendritic cells (dectin-1), as well as interactions with other receptors, mainly expressed by innate immune cells (e.g., Toll-like receptors, complement receptor-3), have raised new attention toward these products as suitable therapeutic agents. We briefly review the characteristics of the glucans from mycelial walls as modulators of the immunity and their possible use as antitumor treatments.

Saleh B.,Al Jabal Al Gharbi University
IABSE Conference, Nara 2015: Elegance in Structures - Report | Year: 2015

The paper presents studies on experimental investigation of beam-to-column joint behaviour in standard and exceptional events situations, This assessment is done to form a picture of the general the behavior of full scale frameworks at both the level of the global behavior of the framework, in terms of its load-displacement characteristic, and of the local behavior of joints in terms of their moment-rotation characteristics, and evaluates details about the interaction of the joint elements and how they work together in a balanced manner. The paper addresses these problems using two types of joints flush and extended end-plate for the evaluation of joint moment-rotation response when exposed to negative and positive moments together.

Kharwat A.S.,Al Jabal Al Gharbi University
Journal of Communications | Year: 2014

Conventional precoded spatial multiplexing multiple-input multiple-output (MIMO) systems using limited feedback are mainly based on the notion of time invariant channels throughout transmission. Consequ-encely, the precoding matrix can be found during the training symbols and used over the subsequent data symbols. In this paper, a more practical system where the channel varies from one block of symbols to another is considered. In such scenario, the precoding matrix designed at the receiver based on the previous training symbols becomes outdated, which results in significant system performance degradation. In order to avoid this problem, and reduce performance degradation, we propose the use of a Kalman filter linear predictor at the receiver to provide the transmitter with the precoding matrix for the next block of symbols. The performance of this method is assessed using computer simulation, and the obtained results for the proposed channel prediction demonstrate improved bit error rate performance for time-varying Rayleigh fading channels. © 2014 Engineering and Technology Publishing.

Sharma H.K.,Al Jabal Al Gharbi University
Anti-Corrosion Methods and Materials | Year: 2012

Purpose: The purpose of this paper is to present the results of some corrosion inhibition studies of brass in 3N HNO3 by gemini surfactants. Design/methodology/approach: Gemini surfactants namely: N-trimethyl butane-diyl-1,2-ethane-bis-ammonium bromide (BEAB), N-hexane-diyl-1,2-ethane-bis-ammonium bromide (HEAB), N-dodecane-diyl-1,2-ethane-bis-ammonium bromide (DDEAB) and N-hexadecane-diyl-1,2-ethane-bis-ammonium bromide (HDEAB) were synthesized in the laboratory and their influence has been investigated for controlling the dissolution of brass in 3N HNO3. Weight loss, potentiodynamic polarization and electrochemical impedance have been employed for the study. Weight loss experiments were performed as per standard method (ASTM, 1987). Potentiodynamic polarization studies were carried out using EG&G PARC potentiostat/galvanostat (model 173), universal programmer (model 175) and X-Y recorder (model RE 0089) and impedance measurements were carried out with an EG&G PAR (model 5301 A) lock-in-amplifier, using an IBM computer. Findings - The inhibition efficiency for all the gemini surfactants increases with increase in concentrations. The maximum inhibition efficiency of each inhibitor was achieved at 250 ppm concentration. The inhibition efficiency of all the inhibitors decreases on increasing the temperature from 30 to 50°C. The results of potentiodynamic polarization studies revealed that all the compounds were mixed type inhibitors and inhibit the corrosion of brass by blocking the active sites of the metal. The adsorption of the compounds on brass surface in 3N HNO3 has been found to obey the Langmuir adsorption isotherm. Originality/value: The paper provides information regarding corrosion inhibition of brass in 3N HNO3, the mechanism of the inhibition on the basis of molecular structures of the inhibitors, activation energy and free energy of adsorption. © Emerald Group Publishing Limited.

Khrwat A.S.,Al Jabal Al Gharbi University
2012 19th International Conference on Telecommunications, ICT 2012 | Year: 2012

In this paper, the performance of limited feedback precoded spatial multiplexing multiple-input multiple-output orthogonal frequency division multiplexing (MIMO - OFDM) systems is investigated in time varying fading channels. Most studies into limited feedback precoded MIMO - OFDM systems are based on the notion of time invariant channels throughout transmission. Therefore, the precoding matrix for each subcarrier can be designed at the receiver in terms of the current channel state, fed back to the transmitter, and used for the subsequent block of data symbols. However, in time varying channels, the feedback information becomes outdated, which results in significant system performance degradation. To mitigate this system performance degradation caused by outdated information due to a delay in the feedback channel, this paper considers a more practical system, where the channel varies from one block of symbols to another. A method is proposed based on modelling the channel as an autoregressive (AR) model and using a Kalman filter linear predictor at the receiver to predict the channels states, required to design the precoding matrices for the next OFDM symbol carriers whose indexes are fed back to the transmitter. The performance of this method is investigated using computer simulation, and the results obtained for the proposed channel prediction demonstrate improved bit error rate performance for time-varying Rayleigh fading channels, even in systems with high mobility © 2012 IEEE.

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