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Mahoorkar S.,HKES SN Institute of Dental science and Research | Jain A.,Dental XPERTS | Cauvery K.,PDU Dental College | Kumar P.,Al Badar Rural Dental College and Hospital | Havale R.,AMES Dental College
Journal of Clinical and Diagnostic Research | Year: 2014

An implant-level impression is often desired for designing and fabricating an implant-supported fixed restoration. This clinical report describes the use of modified press-fit metal implant fixture mount as an impression coping for making an impression of closely placed implants. The fixture mount is easier to manipulate, time saving and more comfortable for both the clinician and patient because the implant fixture mount is connected to the implant by pressing on instead of screwing. As compared to plastic press fit impression coping, metal fixture mount will not distort when modification of fixture mount are required in convergently or closely placed implants. It has the advantage of both the open-tray and closed-tray implant impression techniques. Source

Ramesh S.,VP Dental College | Patil V.,Hkes S N Institute Of Dental Science And Research | Sharma M.,VP Dental College | Patil S.,Al Badar Rural Dental College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2014

As the aesthetic demands are increasing day by day, demand of immediate restoration or replacement of teeth is also increasing. Because of this, immediate implant placement, along with immediate loading of implant, is a favourite treatment option for patients as well as dentists. This case report discusses the immediate implant loading in compromised maxillary anterior region, in which patient got immediate restoration of edentulous area. More importantly, from the patients' points of view, immediate loading can produce positive social and psychological effects. Source

Keshav R.,Vydehi Institute of Dental science and Research | Narayanappa U.,Al Badar Rural Dental College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2015

Background and objectives: Expression of Proliferating Cell Nuclear Antigen (PCNA) well-correlates with the cell division. The suprabasal expression of PCNA is considered to be a marker of dysplastic oral mucosa indicating a special proliferative cellular state in those lesions. Oral submucous fibrosis (OSMF) is considered to be a premalignant condition with potential to get transformed into oral squamous cell carcinoma (OSCC). The present study was done to assess the PCNA expression in different grades and in different layers of epithelium of OSMF and to compare the expression of PCNA in OSMF with OSCC. Materials and Methods: A group of 40 histopathologically diagnosed, formalin fixed, paraffin embedded tissue samples were included in study. The study group was further divided into 2 groups; 30 OSMF and 10 OSCC. Theses samples were collected from Department of Oral and Maxillofacial Pathology, Government Dental College and Research Institute, Bangalore. The samples were subjected to immunohistochemical method using indirect immunoenzyme LSAB method. Results: All 40 cases showed positivity for PCNA. The percentage of positive cells was more in basal and suprabasal layer both in OSMF and OSCC, whereas the greater percentage of positive cells was seen in the superficial layer of OSCC. All OSMF cases showed positive expression in basal and suprabasal layer and only 77% of cases showed positive PCNA expression in the superficial layer with variable immunoreactivity and 23% did not show any positive staining in the superficial layer. The percentage of positive cells and the intensity of staining increased as the disease severity increased in OSMF. Conclusion: Increased proportion of cells expressed PCNA staining which are in proliferative layers of OSMF. This biomarker provides an insight into the biological behaviour of the condition that substantiates its potentially malignant nature and may also provide an intermediate end point in chemotherapeutic trials. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source

Beedimani R.S.,Kamineni Academy of Medical science and Research Center | Kalmath B.,Al Badar Rural Dental College and Hospital
International Journal of Pharma and Bio Sciences | Year: 2014

Phosphodiesterase 5 (PDE5) is a key enzyme involved in the regulation of cGMPspecific signaling pathways in normal physiological processes such as smooth muscle contraction and relaxation. Initially, PDE5 inhibitors were developed as potential antianginal agents, but early clinical results were disappointing and the focus of these drugs moved to the treatment of Erectile Dysfunction (ED) based on the findings that nitric oxide and cyclic guanosine monophosphate were important mediators of penile erection. The overall goal of this review is to provide a comprehensive understanding of the current and potential therapeutic roles of the PDE5 enzyme inhibitors. Novel PDE5 inhibitors are highly selective for the PDE5 isoenzyme, and this may translate into potential novel indications and fewer adverse systemic effects. Larger scale, well designed clinical trials are needed to ascertain the safety, efficacy and costeffectiveness of PDE5 inhibitors in the future treatment of urological, cardiovascular, gastrointestinal, and central nervous system disorders. Source

Katti G.,Al Badar Dental College and Hospital | Khan M.M.,Al Badar Dental College and Hospital | Chaubey S.S.,Al Badar Rural Dental College and Hospital | Amena M.,Al Badar Rural Dental College and Hospital
BMJ Case Reports | Year: 2016

Cemento-ossifying fibroma is a benign growth, considered to originate from the periodontal ligament. It is often encapsulated and predominantly located in the mandible, and presents as a slow-growing lesion, but may cause deformity if left untreated. The definitive diagnosis of these lesions requires integration of its clinical, radiological and histological features. We present a case of cemento-ossifying fibroma in relation to the lower left one-third of the face, and its management. © 2016 BMJ Publishing Group. All rights reserved. Source

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