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Switonski A.,Polsko Japonska Wyzsza Szkola Technik Komputerowych | Switonski A.,Silesian University of Technology | Blachowicz T.,Silesian University of Technology | Zielinski M.,Akademia Medyczna we Wroclawiu | And 3 more authors.
Przeglad Elektrotechniczny

We have proposed and deployed prototyped multispectral capturing device for the ophthalmic diagnosis. The main component of the device are slit lamp, liquid crystal tunable filter and high sensitive monochrome camera. The applied hardware allows to obtain 21 spectral channels in the visible light range. The device has been calibrated based on the captured images of the colorchecker colors with known RGB and spectral values.. The proposed device is focused on the diagnoses of cancer, PEX, galucoma and diabetic retinopathy,. Source

Mikulewicz M.,Akademia Medyczna we Wroclawiu | Chojnacka K.,Wroclaw University of Technology | Janeczek M.,Wroclaw University of Environmental and Life Sciences | Szymkowski J.,Wroclaw University of Technology | And 4 more authors.
Przemysl Chemiczny

A new method for assessing the biocompatibility of materials used in orthodontics in the pig as a model organism was developed. Exptl. plates simulating orthodontic appliances were fixed in a pig snout (2 a pig) on the internal side of the cheek to study the exposure to toxic metals. No differences between expt. and control animals in growth rate and health were obsd. Source

Jedrejko M.,Akademia Medyczna we Wroclawiu | Skoczynska A.,Akademia Medyczna we Wroclawiu
Medycyna Pracy

Introduction: Acquired reversible dyschromatopsia has been associated with occupational exposure to mercury vapor. Earlydetected impairments in color discrimination precede adverse permanent effects of mercury, so they may help to monitor the health of the exposed workers. The aim of this study was to evaluate the color discrimination ability in this group of workers, using Lanthony D-15d test. Material and methods: Employed in a chloralkali plant, 27 male workers exposed to mercury vapor and 27 healthy white-collar workers (control group) were qualified for the study. To assess color discrimination, the Lanthony 15-Hue desaturated test (Lanthony D-15) was used. In order to investigate quantitative and qualitative results, the Lanthony D-15d scoring software was performed. Urinary mercury was determined using flameless atomic absorption spectrometry. Results: In the workers exposed to mercury vapor, urine mercury concentration was 117.4±62.6 μg/g creatinine on average compared with 0.279±0.224 mg/g creatinine in the control group (p < 0.0001). In 18 exposed persons (66.7%), the results of the Lanthony D-15d test showed qualitative changes, which are borderline corresponding to the early stage of developing dyschromatopsia type III. The quantitative analysis of the test findings indicated a significantly higher value of the Color Confusion Index (CCI) in the right eye in the exposed group compared to the control group (p = 0.01), with no significant difference in the CCI in the left eye. In the exposed group, the CCI in the right eye was significantly higher than the CCI in the left eye (p = 0.0005). There was neither correlation between CCI and the level of urinary mercury, nor between CCI and duration of exposure. Conclusions: The results showed that the Lanthony D-15d test is useful in the detection of early toxic effects in the eyesight of the workers exposed to mercury vapor. The observed color vision impairments are borderline corresponding to the early stage of developing dyschromatopsia type III. © Instytut Medycyny Pracy im. prof. J. Nofera w Łodzi. Source

Gladysz A.,Akademia Medyczna we Wroclawiu | Fleischer-Stepniewska K.,Akademia Medyczna we Wroclawiu
Polski Merkuriusz Lekarski

According to the report of the National Institutes of Health (NIH) in Bethesda, Maryland, USA, infectious diseases are one of the eight most common causes of illness since 1990. Due to breaking down barriers of interspecies, the state of immunosuppression, widespread use of antibiotics, there are still new threats, and earlier known to cause disease of a different course, resistant to previously effective therapies. The evolution of infectious diseases directs our attention primarily on the validity of the principles of rational antibiotic use to the increasing resistance of microorganisms. The movements of the opponents of vaccination appear to be more effective than the planned education of doctors and their patients, and the absence of sufficient administrative control performance of vaccination, raises a serious problem in contemporary clinical researcher. Infectious diseases will continue to exist as long as host organisms. It is important to the fight against them, making the best use of expertise and funds. In such a situation, the balance may move to benefit us - humans. Source

Introduction: Chronic kidney disease (CKD) leads to bone and mineral complications, which are manifested, among others, by hyperparathyroidism, calcium-phosphate and vitamin D balance disturbances. The results of investigation assessing the usefulness of CAP/CIP ratio, (cyclase activating PTH/cyclase inactive PTH) as a marker of bone turnover and bone disturbances in this group of patients are contradictory. Aim of the study: was to estimate the concentration of CAP and CIP of parathormone, connection with selected calcium-phosphate balance parameters and usefulness of CAP/CIP ratio to differentiate bone mineral density in patients with CKD treated with repeated haemodialysis. Material and methods: The study included 31 children aged 5 to 18 years. Group I - 15 haemodialysed children. Group II - 16 healthy children. The patients underwent the following serum measurements: calcium concentration (Ca), inorganic phosphate (P), 1.25-dihydroxyvitamin D, parathormone (intact PTH), and CAP, CIP were evaluated with Scantibodies Laboratory Inc test. In group I the densitometric examination was done using the Lunar DPX-L system, performing the overall bone measurement. Results: In children from group I the average values of iPTH concentration and both CIP and CAP components were significantly elevated (p<0.05) as compared to group II. CAP/CIP ratio in group I was <1; in healthy children >1. Average concentrations of Ca and 1.25(OH)2D in serum of group I were lowered, although without statistical significance in comparison with group II. CAP/CIP ratio does not differentiate the children with bone disturbances. Densitometric examination revealed osteopenic changes in 3 children and osteoporosis in 2 children. There were no statistically significant correlations between the examined parameters. Conclusions: 1. The CIP/CAP ratio does not differentiate the bone mineral density status and it is not associated with biochemical parameters of calcium-phosphate metabolism. 2. This indicates its poor diagnostic utility with reference to mineralization disturbances in children with chronic kidney disease. Source

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