Abiala M.A.,University of Ibadan |
Abiala M.A.,Ajayi Crowther University |
Odebode A.C.,University of Ibadan
Biocontrol Science and Technology | Year: 2015
Phyto-beneficial effects of rhizobacteria specifically Enterobacter species were evaluated on maize seedling health and growth. Out of the 19 isolates examined, two were remarkable in their phosphate solubilization efficiency (PSE > 70%), chitinase enzyme activity (CEA > 85%) and antifungal activity with evidence of no or low disease expression in maize seedling. The selected isolates (OSR7 and IGGR11) were identified and 16S rDNA revealed both isolates as Enterobacter species. Re-evaluation of both isolates ascertains that their combined effects are more effective on maize seedling than their individual effects. Their combinations completely suppressed pathogenic activity of Fusarium verticillioides on maize seedling with evidence of no disease symptoms. Other treatments significantly (p < 0.05) expressed varied maize seedling diseases such as leaf curl and stem rot. Apart from treatment T2 (maize + pathogen), other treatments most especially their combinations significantly (p < 0.05) enhanced seedling height, stem girth, leaf area, nitrogen and potassium contents. The phyto-beneficial effects of these Enterobacter species suggest that they could be employed as bio-inoculant for maize seedling health and growth. © 2014, © 2014 Taylor & Francis.
PubMed | University of Ibadan, Ajayi Crowther University and National Horticultural Research Institute
Type: Journal Article | Journal: BMC complementary and alternative medicine | Year: 2016
Plant extracts were evaluated on poultry bacteria known to be threatening public health. This is to develop better bio-therapeutic agents from plant origin.Bacteria were isolated from water, feed, crop, gizzard and faeces of layer chicken. Isolates of interest (Escherichia coli, Salmonella enteritidis, Pseudomonas aeruginosa and Klebsiella oxytoca) were subjected to antibiotic susceptibility test. Resistant strains were further evaluated against different plant extracts in comparison to Meropenem (control) using agar diffusion method.E. coli had the highest occurrence (53 %), followed by P. aeruginosa (25 %) and then S. enteritidis (13 %) while the least was K. oxytoca (9 %). Virtually all the isolates exhibited multi-antibiotic resistance (MAR) with gross resistance to Amoxicillin, Erythromycin and Cefuroxine. P. aeruginosa (75 %), S. enteritidis (75 %) and E. coli (63 %), had the highest MAR. Out of the 11 (100 %) plant extracts evaluated, 7 (64 %) were outstanding and showed varied levels of antibacterial activity. Specifically, methanol extract of Mangifera indica Julie cultivar leaf (MJLM) had the highest antibacterial activity, followed by Euadenia trifoliata stem bark (TB03) and Euadenia eminens leaf (TB05). P. aeruginosa was highly susceptible (81.81 %) to the extracts, followed by S. enteritidis (63.64 %) and then E. coli (27.27 %).MJLM and other extracts have proven to be promising extracts in which to search for bioactive components that can be developed into therapeutic drugs. This may help in the management of antibiotic resistant bacterial isolates from poultry chicken threatening public health.
Identification and comparison of the volatile constituents of fresh and dried leaves of Spondias mombin found in North-central Nigeria: in vitro evaluation of their cytotoxic and antioxidant activities
PubMed | Lagos State University, Al-Hikmah University, Obafemi Awolowo University, Ajayi Crowther University and University Of Abuja
Type: Journal Article | Journal: Pharmaceutical biology | Year: 2016
Various studies have shown that the leaf extracts of Spondias mombin Linn (Anacardiaceae) possess pharmacological properties such as antioxidant and antiviral effects. However, no biological activity from its essential oil has been reported in literature.To analyse the chemical constituents, cytotoxic activity and antioxidant capability of the essential oils from fresh and dried leaves of S. mombin.Hydrodistillation using Clevenger-type apparatus was employed to obtain the essential oil. Oil analysis was performed using an HP 6890 Gas Chromatograph coupled with an HP 5973 Mass Selective Detector. The cytotoxicity bioassay was carried out using the brine shrimp lethality test (10,000-0.01g/mL). Additionally, the reactive oxygen species scavenging potential of the two S. mombin oils (1000-200g/mL) were investigated using a hydroxyl radical scavenging and ferric iron reducing system.Chemical analysis of essential oils from S. mombin revealed the presence of 41 compounds, with predominance of monoterpenoids, sesquiterpenoids and non-terpenoids derivatives. In both fractions, the principal component was -caryophellene (27.9-30.9%), followed by -cadinene (9.7-12.3%). There was an increase in the oxygenated monoterpenoid contents and a concomitant decrease in the amounts of sesquiterpenoids hydrocarbons observed on drying the leaves. The oil obtained from the fresh leaves was more active than that obtained from dried leaves, with LCEssential oil derived from the leaves of S. mombin could hold promise for future application in the treatment of cancer-related diseases.
Adebayo M.A.,Federal University of Rio Grande do Sul |
Adebayo M.A.,Ajayi Crowther University |
Prola L.D.T.,Federal University of Rio Grande do Sul |
Lima E.C.,Federal University of Rio Grande do Sul |
And 7 more authors.
Journal of Hazardous Materials | Year: 2014
A macromolecule, CML, was obtained by purifying and carboxy-methylating the lignin generated from acid hydrolysis of sugarcane bagasse during bioethanol production from biomass. The CMLs complexed with Al3+ (CML-Al) and Mn2+ (CML-Mn) were utilised for the removal of a textile dye, Procion Blue MX-R (PB), from aqueous solutions. CML-Al and CML-Mn were characterised using Fourier transform infrared spectroscopy (FTIR), scanning differential calorimetry (SDC), scanning electron microscopy (SEM) and pHPZC. The established optimum pH and contact time were 2.0 and 5h, respectively. The kinetic and equilibrium data fit into the general order kinetic model and Liu isotherm model, respectively. The CML-Al and CML-Mn have respective values of maximum adsorption capacities of 73.52 and 55.16mgg-1 at 298K. Four cycles of adsorption/desorption experiments were performed attaining regenerations of up to 98.33% (CML-Al) and 98.08% (CML-Mn) from dye-loaded adsorbents, using 50% acetone+50% of 0.05molL-1 NaOH. The CML-Al removed ca. 93.97% while CML-Mn removed ca. 75.91% of simulated dye house effluents. © 2014 Elsevier B.V.
Fasola O.S.,Ajayi Crowther University
Electronic Library | Year: 2015
Purpose - The purpose of this paper is to report on research that examined librarians' perception and acceptance of use of Facebook and Twitter in promoting library services in Oyo state, Nigeria. Design/methodology/approach - The survey design and interview were used to collect data from librarians in Oyo state. The questionnaire contained questions that are pertinent to the issues being investigated. The 81 responses (81 per cent) received were processed, analysed and results presented. Findings - The paper reveals that majority of the libraries in Oyo state, Nigeria, have Facebook profiles, though minority have Twitter accounts. Librarians in Oyo state, Nigeria, have high perception and acceptance of using Facebook and Twitter to promote library services. Findings also reveal that librarians in academic and special libraries in Oyo state, Nigeria, are more highly receptive to use of Facebook and Twitter to promote library services. Findings revealed further that younger librarians showed more positive perception and higher acceptance. Research limitations/implications - While the research was limited to librarians in Oyo state, Nigeria, it has applications to librarians and libraries all over Nigeria. Practical implications - This research provides information on the perceptions and acceptance of social media tools (Facebook and Twitter) in promoting library services. The findings may help provide information to library heads on adopting new and popular technologies to bring the library closer to the user and attract more users and on why it is not being used where they are provided. Originality/value - At the time of completing this study, research had mainly been on librarians' use of social media for personal issues not on librarians' perception and acceptance of using it to promote library services. This research also focuses on libraries in Oyo state having a presence on Facebook and Twitter to promote library service and direct and prompt communication with their users. © 2015 Emerald Group Publishing Limited.
Obaleye J.A.,University Of Ilorin |
Adediji J.F.,Ajayi Crowther University |
Adebayo M.A.,Ajayi Crowther University
Molecules | Year: 2011
A bioactive ligand, 2,5-diamino-1,3,4-thiadiazole (L), derived from semicarbazide hydrochloride, and its metal complexes were prepared and characterized. The complexes were characterized using elemental, infra-red, ultraviolet/visible, magnetic moment, atomic absorption, thin layer chromatography and molar conductance measurements. The IR data revealed that the ligand (L) behaved as a tridentate neutral ligand. It coordinated to the metal ion via sulphur and nitrogen of the amines. The molar conductance data reveal that the chelates are non-electrolytes. From the Ultraviolet/Visible spectra and magnetic moment data, the complexes were found to have octahedral geometrical structure. In vivo evaluation of the antimicrobial activities of the metal complexes and the ligands showed greater activity against some micro-organisms when compared to the parent compounds. The chelates do not show toxicity against the activities of enzymes from homogenates of liver, kidney and serum in experimental rats. © 2011 by the authors; licensee MDPI, Basel, Switzerland.
Emike A.J.,Ajayi Crowther University
International Journal of Applied Linguistics and English Literature | Year: 2013
The paper is an extra-linguistic critique of Austin’s speech act theory. In the context of the paper, extra-linguistic issues capture those factors that “legitimize” violations from the norms of English which are evident in Austin’s theory. We investigate the strengths and weaknesses of the theory from a socio-pragmatic perspective, exploring discursively, the Nigerian existential experience. The critique hinges on three evolved theoretical concepts (Geoimplicature, Emergent Context and Pragmadeviant) in the investigation of the strengths and weaknesses of Austin’s speech act theory. The study finds out that despite the strengths of the theory, some postulations therein are bedeviled by the dynamics of human communication. Conclusively, the paper contends for an “illocutionary component” of meaning as opposed to the age-long “propositional component” of meaning. © Australian International Academic Centre, Australia.
Ayodabo J.O.,Ajayi Crowther University
International Journal of Applied Linguistics and English Literature | Year: 2013
This paper has looked at the dynamics of the structures of headlines. Related literature was reviewed on functions and influence of the print media, mass media and language development, and studies in headlines, to give the work the necessary theoretical foundation. The study employed survey approach to look at reportage of headlines of some newspapers in Nigeria. Three questions guided this study: What are the types of headlines cast for the stories? What is the syntactic structure of the headlines? What is the level of social responsibility displayed by the editors, in casting the headlines? A total of 24 headlines were purposively collected as data, and analyzed. The analysis has revealed that ‘plain’, ‘headlines with pointers’, and ‘speech as headlines’ characterized our data. Also, most of the headlines are cast in simple sentence structures. This result is significant for mass media teachers as they apply principles and theories of language, in their business of teaching mass media courses, daily. © Australian International Academic Centre, Australia.
Olayinka E.T.,Ajayi Crowther University |
Ore A.,Ajayi Crowther University
Research Journal of Pharmacology | Year: 2012
Clarithromycin is a well established, semi synthetic, second generation macrolide antibiotic for respiratory, disseminated mycobacterial, skin and Helicobacter pylori infections. Although, this drug has proven to be relatively safe, hepatic dysfunction including increased hepatocellular and/or cholestatic hepatitis with or without jaundice has been infrequently reported with its use. This study was therefore designed to investigate the toxic potentials of two different doses of clarithromycin (Claricin®) in rats. About 30 rats (Wistar strain) weighing between 180-220 g were completely randomised into 3 treatment groups. Group 1 (Control) received physiological saline while group 2 and 3 were administered 8.8 and 17.6 mg kg -1 of clarithromycin (Claricin®) respectively twice daily for 7 days. Total billirubin, creatinine and urea levels were significantly (p<0.05) elevated in the plasma of the rats that received the two doses of Claricin® by 62 and 94.6, 60 and 122% and 22 and 31.8%, respectively when compared to the control. Activities of ALP, ALT, AST and GGT were also significantly (p<0.05) higher in the plasma of animals treated with the two doses of the drug by 35 and 44.1%, 17 and 30.9%, 22 and 35.3% and 58 and 133.9%, respectively. Plasma lipid profiles revealed a significant increase (p<0.05) in total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides in the two treated groups by 14 and 27.9%, 21 and 43.42%, 19 and 33.64% 15 and 46.2%, respectively. A significant (p<0.05) increase in the MDA level by 36 and 55%, respectively in the two treated groups was also observed. Furthermore, the two doses of clarithromycin significantly (p<0.05) reduced the hepatic levels of ascorbic acid and reduced glutathione (GSH) by 26.2 and 40% and 55 and 73%, respectively with a concomitant reduction in activities of hepatic GST by 23 and 36%, respectively. Similarly, there was a significant reduction in the activities of hepatic catalase and SOD by 46 and 51.9% and 34 and 52%, respectively in the clarithromycin treated groups. Liver histopathology revealed a mild periportal cellular infiltration by mononuclear cells and severe central venous congestion respectively in the two dose groups while foci of haemorrhages in the renal cortex were observed in the 17.6 mg kg -1 Claricin® group. These data indicate that oral administration of clarithromycin has adverse effects on both enzymic and non-enzymic antioxidant status and induces oxidative stress as well as renal and liver damages in rats. © Medwell Journals, 2012.
Ore A.,Ajayi Crowther University |
Olayinka E.T.,Ajayi Crowther University
Biochemistry Research International | Year: 2015
Moxifloxacin is a broad spectrum fluoroquinolone antibacterial agent. We examined the hepatic redox status and plasma biomarkers of nephrotoxicity and hepatotoxicity in rat following administration of moxifloxacin (MXF). Twenty-four Wistar rats, 180-200 g, were randomized into four groups (I-IV). Animals in group I (control) received 1 mL of distilled water, while animals in groups II, III, and IV received 1 mL each of MXF equivalent to 4 mg/kg b.w., 8 mg/kg b.w., and 16 mg/kg b.w., respectively. After seven days, plasma urea, bilirubin, and creatinine were significantly (P < 0.05) elevated in the MXF-treated animals. Activities of alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase were significantly increased in the plasma of MXF-treated animals compared to control. Also plasma total cholesterol, HDL-cholesterol, LDL-cholesterol, and triglycerides increased significantly in the MXF-treated groups relative to control. Moreover, MXF triggered a significant decrease in hepatic catalase, superoxide dismutase, and glutathione-S transferase activities. Likewise, MXF caused a decrease in the hepatic levels of glutathione and vitamin C. A significant increase in hepatic MDA content was also observed in the MXF-treated animals relative to control. Overall, our data suggest that the half-therapeutic, therapeutic, and twice the therapeutic dose of MXF induced nephrotoxicity, hepatotoxicity, and altered hepatic redox balance in rats. © 2015 Ayokanmi Ore and Ebenezer Tunde Olayinka.