Hardwick, MA, United States
Hardwick, MA, United States

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Patent
Aileron Therapeutics | Date: 2016-09-28

Provided are crystalline , -disubstituted amino acids and their crystalline salts containing a terminal alkene on one of their side chains, as well as optionally crystalline halogenated and deuterated analogs of the , -disubstituted amino acids and their salts; methods of making these, and methods of using these.


Patent
Aileron Therapeutics | Date: 2016-08-02

The present invention provides peptidomimetic macrocycles capable of modulating growth hormone levels and methods of using such macrocycles for the treatment of disease.


Patent
Aileron Therapeutics | Date: 2016-04-08

The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production.


Patent
Aileron Therapeutics | Date: 2016-04-21

The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.


Patent
Aileron Therapeutics | Date: 2016-03-18

Methods for treating liquid cancer, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a liquid cancer, determined to lack a p53 deactivation mutation, in a subject.


Patent
Aileron Therapeutics | Date: 2016-07-01

The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of viral disease.


Patent
Aileron Therapeutics | Date: 2016-04-07

The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production.


Patent
Aileron Therapeutics | Date: 2015-09-02

The present invention provides peptidomimetic macrocycles capable of regulating HIF1 and methods of using such macrocycles for the treatment of diseases.


Patent
Aileron Therapeutics | Date: 2016-04-07

The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of viral disease.


Patent
Aileron Therapeutics | Date: 2016-04-07

The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of viral disease.

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