Nagoya-shi, Japan
Nagoya-shi, Japan

Aichi Mizuho College is a private university with campuses in Mizuho-ku, Nagoya and Toyota, Aichi in Japan. The predecessor of the school, Aichi Mizuho Junior College, a junior college, was established in 1940, and it became a four-year college in 1993. Wikipedia.

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PubMed | Fukuoka University, Comprehensive Health Science Center Aichi Health Promotion Foundation Higashiura cho Aichi Japan, Diabetes Center Tenri Yorozu sodansho Hospital Tenri Japan, Obesity and Diabetes Center Shimabara Hospital Kyoto Japan and 4 more.
Type: Journal Article | Journal: Journal of diabetes investigation | Year: 2016

The beta-3 adrenergic receptor (ADRB3), primarily expressed in adipose tissue, is involved in the regulation of energy metabolism. The present study hypothesized that ADRB3 (Trp64Arg, rs4994) polymorphisms modulate the effects of lifestyle intervention on weight and metabolic parameters in patients with impaired glucose tolerance. Data were analyzed from 112 patients with impaired glucose tolerance in the Japan Diabetes Prevention Program, a lifestyle intervention trial, randomized to either an intensive lifestyle intervention group or usual care group. Changes in weight and metabolic parameters were measured after the 6-month intervention. The ADRB3 polymorphisms were determined using the polymerase chain reaction restriction fragment length polymorphism method. Non-carriers showed a greater weight reduction compared with the carriers in both the lifestyle intervention group and usual care group, and a greater increase of high-density lipoprotein cholesterol levels than the carriers only in the lifestyle intervention group. ADRB3 polymorphisms could influence the effects of lifestyle interventions on weight and lipid parameters in impaired glucose tolerance patients.


Yamane M.,Aichi Mizuho College | Ohnishi N.,Mie Prefectural College of Nursing | Matsumoto T.,Chukyo University
International Journal of Sports Medicine | Year: 2015

This study examined the effects of regular post-exercise cold application on muscular and vascular adaptations induced by moderate-intensity resistance training. 14 male subjects participated in resistance training: 5 sets of 8 wrist-flexion exercises at workload of 70-80% of the single repetition maximum, 3 times a week for 6 weeks. 7 subjects immersed their experimental forearms in cold water (10±1°C) for 20 min after wrist-flexion exercises (cooled group), and the other 7 served as control subjects (noncooled group). Measurements were taken before and after the training period; wrist-flexor thickness, brachial-artery diameter, maximal muscle strength, and local muscle endurance were measured in upper extremities. Wrist-flexor thicknesses of the experimental arms increased after training in both groups, but the extent of each increase was significantly less in the cooled group compared with the noncooled group. Maximal muscle strength and brachial-artery diameter did not increase in the cooled group, while they increased in the noncooled group. Local muscle endurance increased in both groups, but the increase in the cooled group tended to be lower compared to the noncooled group. Regular post-exercise cold application to muscles might attenuate muscular and vascular adaptations to resistance training. © Georg Thieme Verlag KG Stuttgart New York.


Yamane M.,Aichi Mizuho College | Oida Y.,Chukyo University | Ohnishi N.,Mie Prefectural College of Nursing | Matsumoto T.,Chukyo University | Kitagawa K.,Chukyo University
European Journal of Applied Physiology | Year: 2010

The purpose of the present study was to clarify the effects of wind and rain on peripheral heat loss by non-exercising minimally clothed humans in a mildly cold environment. Seven healthy young male subjects wearing only shorts rested in a standing position for 20 min at an ambient temperature of 15°C under three conditions: without exposure to wind or rain (CON), with exposure to wind (3 m/s) (WIND) and with exposure to wind (3 m/s) and rain (40 mm/h) (WIND + RAIN). Mean heat loss measured using a heat flux transducer was significantly greater in the subjects exposed to WIND + RAIN compared to those exposed to CON and WIND conditions (p < 0.01). Metabolic heat production was significantly greater under WIND + RAIN than under CON and WIND (p < 0.01). Decrease in heat storage was significantly larger at WIND + RAIN compared with CON and WIND (p < 0.01). Mean skin temperature was significantly lower under WIND + RAIN than under CON and WIND conditions (p < 0.01). These results indicate that peripheral heat loss significantly increases when humans are exposed to wind and rain for a short period (20 min) under a mildly cold condition. © 2010 Springer-Verlag.


PubMed | Aichi Mizuho College, Mie Prefectural College of Nursing and Chukyo University
Type: Journal Article | Journal: International journal of sports medicine | Year: 2015

This study examined the effects of regular post-exercise cold application on muscular and vascular adaptations induced by moderate-intensity resistance training. 14 male subjects participated in resistance training: 5 sets of 8 wrist-flexion exercises at workload of 70-80% of the single repetition maximum, 3 times a week for 6 weeks. 7 subjects immersed their experimental forearms in cold water (101C) for 20min after wrist-flexion exercises (cooled group), and the other 7 served as control subjects (noncooled group). Measurements were taken before and after the training period; wrist-flexor thickness, brachial-artery diameter, maximal muscle strength, and local muscle endurance were measured in upper extremities. Wrist-flexor thicknesses of the experimental arms increased after training in both groups, but the extent of each increase was significantly less in the cooled group compared with the noncooled group. Maximal muscle strength and brachial-artery diameter did not increase in the cooled group, while they increased in the noncooled group. Local muscle endurance increased in both groups, but the increase in the cooled group tended to be lower compared to the noncooled group. Regular post-exercise cold application to muscles might attenuate muscular and vascular adaptations to resistance training.


Ito R.,Nihon Fukushi University | Nakano M.,Aichi Toho University | Yamane M.,Aichi Mizuho College | Amano M.,Tokai Gakuen University | Matsumoto T.,Chukyo University
International Journal of Sports Medicine | Year: 2013

Environmental factors tend to influence the performance of individuals who exercise for extended periods. The present study aimed to determine energy metabolism while running in cold, wet conditions using a climatic chamber that can precisely simulate rainy conditions. 7 healthy men (age, 23.3±2.9 (SD) y; height, 168.6±7.5 cm; weight, 65.9±8.1 kg; V. O 2max, 52.0±5.7 mLkg- 1min- 1) ran on a treadmill at 70% ̇VO2max intensity for 30 min in a climatic chamber at an ambient temperature of 5°C in the presence (RAIN) or absence (CON) of 40 mm/h of precipitation. Expired air, esophageal temperature, heart rate, mean skin temperature, rating of perceived exertion and blood samples were measured. Esophageal temperature and mean skin temperature were significantly lower (P<0.05) in RAIN than in CON all. Minute ventilation, oxygen consumption and levels of plasma lactate and norepinephrine were significantly higher (P<0.05) in RAIN than in CON. In conclusion, the higher oxygen consumption and plasma lactate in RAIN indicated that energy demand increases when running in cold conditions. © 2013 Georg Thieme Verlag KG Stuttgart · New York.


Negishi J.N.,Hokkaido University | Negishi J.N.,Japan Aqua Restoration Research Center | Tamaoki H.,Hokkaido University | Watanabe N.,Hokkaido University | And 4 more authors.
Limnology | Year: 2014

Identification of landscape structures that predict the distribution of aquatic organisms has the potential to provide a practical management tool for species conservation in agricultural drainage channels. We tested the hypothesis that sites with imperiled freshwater mussels have distinct rural landscape structures and are characterized by the presence of diverse fish communities. In central Japan, the proportion of developed land use in surrounding areas was compared among sites with mussel populations (mussel sites) and randomly chosen sites (random sites) across multiple spatial scales (with a radius ranging from 100 to 3,000 m). Mussel sites were characterized by a much lower proportion of developed land (mean 5-18 %) compared with random sites (mean 32-35 %) at a scale of ≤300 m. The areas that met the landscape criteria for mussel sites across multiple scales constituted only 0.23 % of the area that was presumed to have suitable slope and elevation as a mussel habitat. Landscape metrics derived from mussel sites to locate unknown populations had a low predictability (16.7 %). Sites with mussels were located close to each other and had fish communities with higher taxonomic diversity than in sites without mussels. In addition, mussel taxonomic richness was a good predictor of fish community diversity. The quantitative measures of landscape structure may serve as a useful tool when prioritizing or identifying areas for conservation of mussels and fish if spatially autocorrelated distribution of habitat and other critical environmental factors such as habitat connectivity are also considered. © 2014 The Japanese Society of Limnology.


Ito T.,Hokkaido University of Education | Kato M.,Nagoya University | Tsuchida H.,Aichi Mizuho College | Harada E.,Iwade Research Institute of Mycology | And 2 more authors.
Food Science and Technology Research | Year: 2011

We measured the anti-oxidative and anti-inflammatory activities of hot water extracts prepared from 11 species of mushrooms. Anti-oxidative activity was evaluated using the oxygen radical absorbance capacity method, and anti-inflammatory activity was examined by measuring the inhibition of lysine chloramine formation by hypochlorous acid. Hot water extracts of Grifola gargal (G. gargal) showed the strongest anti-oxidative activity and inhibitory effects on lysine chloramines. Hot water extracts of G. gargal were evaluated by HPLC and divided into 8 fractions. The most active fraction among these 8 fractions was further purified by preparative HPLC. The active component isolated by HPLC was identified as ergothioneine (EGT) using spectral analysis. On HPLC analysis, the EGT content in G. gargal was the highest among the 11 species of mushrooms. We also examined the protective role of EGT by examining the inflammatory response of adipocyte cells induced by tumor necrosis factor-α.


Tsuchida H.,Aichi Mizuho College | Kozukue N.,Uiduk University | Han G.-P.,Uiduk University | Choi S.-H.,Seowon University | And 2 more authors.
Postharvest Biology and Technology | Year: 2010

To elucidate the cause of reported pyruvate accumulation in chilled stored cucumbers (Cucumis sativus L.) cv. 'Toppugurin', we have examined differences in the extent of incorporation of acetate-1,2-14C into the tricarboxylic acid (TCA) cycle and the specific activity of the enzyme citrate synthase between healthy and chilling-injured cucumber tissues stored in the dark for 0, 3, 6 and 12 d at 1°C or 20°C. Radioactive tracing, gas chromatography, and enzyme analysis suggest that the incorporation of acetate into citrate, the distribution of organic acids in the tricarboxylic acid cycle, and the specific activity of citrate synthase in the cold-storage (chilling-injured) cucumber tissues differed from those in the healthy tissues. The observed decrease in citrate synthase activity may be the cause of the observed increase in pyruvate accumulation in the chilling-injured cucumber fruit tissue compared to tissues stored at 20°C. The results also suggest that the increased formation of pyruvate and reduced activity of citrate synthase during cold storage observed in the present study could serve as indicators (biomarkers) of stress-induced changes in chilled cucumbers. Possible mechanisms of the described effects are discussed. © 2010.


Niwa T.,Nagoya University | Yokoyama S.-I.,Chiyoda Corporation | Ito T.,Aichi Mizuho College | Osawa T.,Nagoya University
Phytochemistry Letters | Year: 2010

Daidzein and genistein are the main aglycones of soy isoflavonoid, and have many useful activities in vitro and in vivo. However, equol, a metabolite of daidzein in vivo, has attracted attention due to its stronger activity than that of the naturally occurring isoflavonoids. We subjected the soy isoflavonoids, including the naturally occurring (S)-equol, to mouse adipocytes, and compared the inhibitory activity on the leptin secretion. Equol, daidzein and genistein inhibited the leptin secretion, whereas O-desmethylangolensin had a lower activity. The inhibitory activity of the isoflavones was not affected by the addition of an iNOS inhibitor and an estrogen. © 2010 Phytochemical Society of Europe.


Watanabe H.,Aichi Mizuho College
Journal of Psychotherapy Integration | Year: 2015

The aim of this article is to show why diversified task-oriented psychotherapy (DTOP) is effective. In DTOP, the therapist must understand the psychopathological level of the patient, what the patient wants and what problems the patient has. Considering the psychopathological level and mental problems of the patient, the therapist presents a task as an agenda, as urgent therapeutic goal. The task contents include psychoanalytical problems, cognitive-behavioral problems, and others. The patient accepts, grasps, and then tries to achieve each task. Thus he shares the responsibility for the therapy. By patients achieving tasks, a firm therapeutic alliance is established. Four cases which had serious problems were treated by DTOP. Two cases feared being made redundant at their workplaces. Two cases were in danger of committing crimes. After treatment by DTOP, all the subjects' lifestyles altered dramatically as if they had become different persons. These facts clearly point out the effectiveness of DTOP. DTOP was discussed from various Japanese cultural points of view. DTOP is effective in that it brings about both reflective function (Fonagy, 1998) and coping function in the patients. © 2015 American Psychological Association.

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