Amid R.,Shahid Beheshti University of Medical Sciences |
Raoofi S.,Shiraz University of Medical Sciences |
Kadkhodazadeh M.,Shahid Beheshti University of Medical Sciences |
Movahhedi M.R.,Sharif University of Technology |
Khademi M.,Ahwaz University of Medical science
Biomedizinische Technik | Year: 2013
The aim of this study was to use finite element analysis (FEA) to assess the influence of microthread design at the implant neck on stress distribution in the surrounding bone. A commercially available implant with 3.5 mm diameter and 10.5 mm length was selected and used as a model. For the purpose of designing the microthread implant model, microthreads were added to the implant neck in a computerized model. A force measuring 100 N was then applied to the entire surface of the abutment in the vertical direction. The results showed that in both models, stress was mainly concentrated at the cortical bone adjacent to the neck of the implant. Maximum stress values in the cortical bone surrounding the implant surface periphery were 12 and 6.25 MPa for the microthread and conventional models, respectively. In this study, we conclude that adding a microthread design at the implant neck decreased stress values in the adjacent bone.
PubMed | MAHAK Childrens Hospital, Golestan University of Medical Sciences, Isfahan University of Medical Sciences, High Institute of Research and 9 more.
Type: Comparative Study | Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis | Year: 2016
This study compared the efficacy of Aryoseven with Novoseven to control bleeding episodes in patients with hemophilia A with inhibitors.Sixty-six patients were randomized into 2 groups, with 4 consecutive block randomization. These groups received Aryoseven and Novoseven dosages of 90 to 120 g/kg intravenously every 2 hours.Median (interquartile range) level of factor VIII (FVIII) inhibitor in groups A and B was 15.0 and 19.0 Bethesda Unit (BU) preadministration. Bleeding onset in group A was 1246 1104 minutes and in group B was 2301 1693 minutes (P = .311). The Kavakli global response scores and treatment success rate was comparable in both the groups. The side effects in groups A (9.7%) and B (2.9%) were comparable.Biosimilar recombinant activated FVII is found to be as effective as Novoseven in the treatment of acute joint bleeding in patients with hemophilia with inhibitors. Its usage will decrease the gaps in hemophilia.
Ghazipour A.,Ahwaz University of Medical science |
Alani N.,Shahid Beheshti University |
Ghavami Lahiji S.,Ahwaz University of Medical science |
Akbari Dilmaghani N.,Shahid Beheshti University
Journal of Cranio-Maxillofacial Surgery | Year: 2014
Background Lateral osteotomies are used in rhinoplasty to narrow the nasal bones, close the open roof deformity after hump removal, and achieve symmetry of an asymmetrical framework. But this procedure causes periorbital oedema & ecchymosis. Different techniques have been described for lateral osteotomy. Objective To compare the postoperative ecchymosis and oedema after buccal sulcus lateral osteotomy versus intranasal lateral osteotomy. Methods and materials In a prospective experimental study, buccal sulcus approach was performed on the right side and an intranasal approach performed on the left side of patients randomly. Then blind analysis of postoperative photographs was performed to determine the incidence of oedema and ecchymosis on each side.Results Fifty patients were enrolled in the study after exclusion of unfit patients. On the right side (buccal approach osteotomies), a significantly lower incidence of upper and lower eyelid oedema and upper eyelid ecchymosis was seen on both the 2nd day and after 7th day (P < 0.05). The odds ratio of progression of ecchymosis was 2.66 (OR = 2.66, 95% CI: 1.09-5.52, p = 0.048) in intranasal group compare to buccal sulcus group. No significant complication observed. Conclusion The buccal sulcus approach is a safe method for lateral osteotomy with a lower rate of postoperative oedema and ecchymosis and no significant complications. © 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
PubMed | Shiraz University of Medical Sciences, Tehran University of Medical Sciences and Ahwaz University of Medical Science
Type: | Journal: European journal of clinical nutrition | Year: 2016
Since the main characteristics of Rheumatoid Arthritis (RA) are joint dysfunction caused by inflammation and serious pain, anti-inflammatory agents may alleviate the clinical symptoms in RA. Pomegranate juice is rich in polyphenolic compounds that possess antioxidant and anti-inflammatory activities. This study aimed to determine the beneficial effects of pomegranate extract (POMx) in RA patients.A total of 55 RA patients were enrolled and randomly allocated to an intervention group (n=30) or a control group (n=25). The intervention group received 2 capsules of 250mg POMx and the control group 2 capsules of 250mg cellulose per day for 8 weeks. At the beginning of the study and after 8 weeks, Health Assessment Questionnaire (HAQ) and Disease Activity Score (DAS) 28 were completed and serum concentrations of C-reactive protein (CRP), matrix metalloproteinases 3 (MMP3), malondialdehyde (MDA), glutathione peroxidase (GPx) and erythrocyte sedimentation rate (ESR) were analyzed using standard methods and compared between the two groups.Compared with the placebo group, POMx supplement significantly reduced the score of DAS28 (P<0.001) which could be related to the decrease in swollen (P<0.001) and tender joints (P=0.001) count, pain intensity (P=0.003) and ESR levels (P= 0.03). POMx consumption also decreased HAQ score (P=0.007) and morning stiffness (P=0.04) and increased GPx concentrations (P<0.001). There were no differences in the change in mean MMP3, CRP and MDA levels between two groups.POMx alleviates disease activity and improves some blood biomarkers of inflammation and oxidative stress in RA patients.European Journal of Clinical Nutrition advance online publication, 31 August 2016; doi:10.1038/ejcn.2016.151.
Sarkaki A.R.,Ahwaz University of Medical science |
Haddad M.K.,Kerman Medical University |
Soltani Z.,Kerman Medical University |
Shahrokhi N.,Kerman Medical University |
Mahmoodi M.,Rafsanjan University of Medical Sciences
Journal of Neurotrauma | Year: 2013
Following a traumatic brain injury (TBI), excessive release of proinflammatory cytokines is the major cause of cerebral edema and neuronal loss. This study was designed to examine changes in concentrations of some proinflammatory cytokines-including interleukin-1 beta (IL-1β), interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-α), and transforming growth factor-beta (TGF-β)-in a rat model of TBI in which the animals were treated with different doses of estrogen or progesterone 6 and 24 h after the TBI. Adult female rats were divided into 14 groups. Hormones or vehicle were given intraperitoneally 30 min after a moderate TBI was induced by the Marmarou method. The levels of proinflammatory cytokines in brain were measured at 6 and 24 h after the TBI. A high dose of estrogen (E2) or a low dose of progesterone (P1) increased brain levels of IL-1β 52.7% and 79.2% respectively at 6 h after the TBI. By 24h, IL-1β levels in the brain were 27.5% and 27% lower following administration of estrogen low dose (E1) or E2, respectively. High-dose administration of progesterone reduced brain levels of IL-6 to 45.9% at 6 h after the TBI, and P1 and E1 treatment significantly decreased IL-6 levels at 24 h. Brain levels of TNF-α were 72.5% lower at 6 h after the TBI following P2 treatment and 48.5% higher at 24 hrs following treatment with E2. The levels of TGF-β were also 3.37 times higher 24 h after the TBI following treatment with E1. Both doses of the hormones tested increases TGF-β levels 6 h after the TBI. Based on our findings, we conclude that progesterone and estrogen influence the levels of proinflammatory cytokines either at the primary or secondary stages after a TBI. Accordingly, this study suggests a mechanism by which hormones reduce cerebral edema. © 2013, Mary Ann Liebert, Inc.
Kaykhaei M.A.,Zahedan University of Medical Sciences |
Hashemi M.,Zahedan University of Medical Sciences |
Narouie B.,Zahedan University of Medical Sciences |
Shikhzadeh A.,Zahedan University of Medical Sciences |
And 3 more authors.
Annals of Nutrition and Metabolism | Year: 2011
Background: Several studies show a high prevalence of vitamin D deficiency in Asia. Data regarding the prevalence of vitamin D deficiency in southeast Iran are inadequate. Objectives: The purpose of this study was to determine the prevalence of vitamin D deficiency in Zahedan, a sunny area in southeast Iran. Subjects and Methods: This population-based cross-sectional study was performed on 993 apparently healthy subjects. Serum levels of 25-hydroxy vitamin D (25-OH vit D), parathyroid hormone, calcium, phosphate, and alkaline phosphatase activity were measured. Results: Inadequate vitamin D status was diagnosed in 94.7% of the subjects (25-OH vit D <30 ng/ml). The frequencies of deficiency (<20 ng/ml), insufficiency (20-30 ng/ml), sufficiency (30-150 ng/ml), and toxicity (>150 ng/ml) were 85.2, 9.5, 5.3, and 0.0%, respectively. Conclusion: The results indicate that vitamin D deficiency is common in the population of Zahedan. Based on our results, fortification of milk and the use of supplements is suggested in this region. Copyright © 2011 S. Karger AG, Basel.
Hossein R.,Imam Khomeiny Hospital |
Kambiz M.,Imam Khomeiny Hospital |
Mohammad D.,Ahwaz University of Medical science |
Mina N.,Imam Khomeiny Hospital
Journal of Craniofacial Surgery | Year: 2010
Eagle syndrome is considered a rare disease. It is an aggregation of symptoms that includes neck, throat, and hemifacial pain; sensation of foreign body in the throat; dysphagia; otalgia; and change in voice as a direct result of an elongated styloid process or calcified stylohyoid ligament.The clinical diagnosis is generally difficult and must be confirmed by radiologic imaging. Our patient was a 37-year-old woman who had a 3 years' history of dysphagia and foreign body sensation. Computed tomographic scan showed a long left styloid process and calcification in the upper part of the stylohyoid ligament suggestive of Eagle syndrome. The patient underwent surgical removal of the elongated styloid process through an intraoral approach. The patient became symptom-free at 9 months after the surgery. © 2010 by Mutaz B. Habal, MD.
Ghalayani P.,Isfahan University of Medical Sciences |
Tavakoli P.,Kermanshah University of Medical Sciences |
Eftekhari M.,Ahwaz University of Medical science |
Haghighi M.A.,Isfahan University of Medical Sciences
Turk Patoloji Dergisi | Year: 2015
Focal epithelial hyperplasia or Heck’s disease is an infrequent asymptomatic condition caused by human papillomavirus types 13 or 32 affecting the mucous membrane of the mouth and is commonly seen in young individuals. Firstly, it was described in Indians and Eskimos, but it exists in various populations. We present three cases of Heck’s disease in an Afghan immigrant family group living in Iran that seem to have familial predominance. The disease was identified as oral focal epithelial hyperplasia on the basis of histopathologic and clinical findings. The lesions were reduced significantly after 4 months of good oral hygiene. Dentists should be familiar with the clinical manifestations of these types of lesions that affect the oral cavity. In fact, histopathologic assessment and clinical observation are necessary to establish the diagnosis. © 2015, Federation of Turkish Pathology Societies. All rights reserved.
Patterns of care seeking during episodes of childhood diarrhea and its relation to preventive care patterns: National integrated monitoring and evaluation survey (IMES) of family health. Islamic Republic of Iran
Motlagh M.E.,Ahwaz University of Medical science |
Heidarzadeh A.,Guilan University |
Hashemian H.,Guilan University |
Dosstdar M.,Guilan University
International Journal of Preventive Medicine | Year: 2012
Background: In Iran, diarrheal disease is the fourth cause of under five-year mortality. Proper care-seeking behavior and system-based disease management in the national field will have a great effect in reducing morbidity and mortality. Methods: This nationwide study was performed on a target population of rural and urban communities; in all 31 provinces of the Islamic Republic of Iran. One lakh three thousand three hundred and thirty one (103331) families were sampled by multistage stratified random sampling and were interviewed with a standard data collection form. The collected data was entered into the Stata8.0 software and analyzed by the survey analysis method. Results: Of the 14625(10.1%) children who were reported to have diarrheal diseases two weeks prior to the interview, 8.8% were cured and 1.5% were not. About 70% of them had at least one visit for health seeking the most of patients were seen by (Behvarz) in the rural and by a generala rural health worker pediatrician in the urban areas. About 62% of the patients in urban and 57% in the rural areas had been treated with antibiotics and these rates for ORS were 51% and 65%, respectively. The factors most related to a care-seeking pattern were the level of routine preventive well-child care, number of siblings, child age, and living area. Conclusion: According to this national survey, our health system needs to integrate all the levels of prevention, especially the Integrated Management of Child Illnesses (IMCI) programs with a family physician project. Futher more, there is a great need for empowering the referral system and gate keeping in all referral levels, to make efficient national integrated programs.
Hamid N.,Ahwaz University of Medical science
Journal of Kerman University of Medical Sciences | Year: 2013
Background & Aims: The purpose of the present study was to investigate the effects of Stress Inoculation Training [SIT] on patients with dysfunctional attitudes and primary hypertension. Methods: The study sample included 60 subjects with primary hypertension (32 females & 28 males) referred to special clinics in Ahwaz. Those who had primary hypertension and dysfunctional attitudes based on Beck & Wiszeman Dysfunctional Attitudes Scale (DAS) were selected and after being matched for age, socio-economic status and lack of other diseases, they were randomly divided into experimental and control groups. Experimental group underwent an 8-session Stress Inoculation Training (SIT) program. Finally, all subjects of the two groups were assessed for dysfunctional attitudes and primary hypertension in posttest and three months fallow- up. Results: The results revealed a significant difference between the two groups in dysfunctional attitudes and primary hypertension at posttest and fallow- up. Moreover, experimental group in comparison to the control group showed significant improvement in dysfunctional attitudes and hypertension in posttest and three months follow up. Conclusion: Stress Inoculation Training (SIT) significantly decreased dysfunctional attitudes and primary hypertension; therefore, using SIT in hypertensive patients is recommended.