Ahvaz Jundi Shapour University of Medical science

Ahvāz, Iran

Ahvaz Jundi Shapour University of Medical science

Ahvāz, Iran

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Shokri S.,Zanjan University of Medical Sciences | Hemadi M.,Ahvaz Jundi shapour University of Medical science | Bayat G.,Alborz University of Medical science | Bahmanzadeh M.,Ahvaz Jundi shapour University of Medical science | And 2 more authors.
Andrologia | Year: 2014

Summary: High doses of anabolic-androgenic steroids (AAS) are used by some athletes to increase muscle mass, that is often associated with male infertility. The aim of this study was to investigate the possible cause/s of male infertility using a rat model by analysing sperm quality, including its protamine content and DNA integrity, as well as pregnancy rate. Five groups of male Wistar rats were treated for 10 weeks as follows: nandrolone decanoate (10 mg kg-1 per week) (ND); running exercise (50 min per day, 5 days a week) (EX); Combination of ND and exercise (ND-EX); nandrolone decanoate solvent (Sham); and control without any injection or exercise (CO). Deterioration in sperm quantity was observed in all test groups (P ≤ 0.01). The frequency of fertile rats was decreased in the ND-EX and ND groups (P ≤ 0.05). Chromomycin-A3 staining showed a protamine deficiency in the epididymal spermatozoa in the ND-EX rats (P ≤ 0.05). Chromatin analysis indicated an abnormal maturation of the sperm nuclei in all test groups compared with the controls (P ≤ 0.05). TUNEL analyses showed a highly significant increase in apoptosis in the EX, ND, and ND-EX groups (P ≤ 0.01). Our data show that a combination of exercise and high doses of nandrolone decanoate negatively influences the DNA integrity and protamine content resulting in lower sperm quality and reduced pregnancy rate. © 2013 Blackwell Verlag GmbH.


Behzadi K.,Ahvaz Jundi Shapour University of Medical science | Jafarirad S.,Ahvaz Jundi Shapour University of Medical science | Mousavi P.,Ahvaz Jundi Shapour University of Medical science | Saki O.,Health Science University
Iranian Journal of Obstetrics, Gynecology and Infertility | Year: 2016

Introduction: Premenstrual syndrome is a set of changes in mood, physical and behavioral symptoms that occurs before or during menstruation. Due to the multiple beneficial effects mentioned in articles indicating the usefulness of black currant for controlling the points and procedures that are known in the pathogenesis of premenstrual syndrome, and due to unavailability of a study which evaluated the consumption of black currant as a method of alternative medicine, this study was performed with aim to evaluate the effect of dried black grape (Vitis Vinifera) on clinical, psychological, and behavioral symptoms of premenstrual syndrome. Methods: This clinical trial was performed on 201 students residing in the dormitory of Ahvaz Jundi Shapour University of Medical Sciences in 2015. After two periods of screening, the subjects were divided into two groups of intervention and control. The intervention group received daily 90 g dried black seed grape seven days before menstruation for two consecutive menstruation cycles. After one and two months of intervention, the severity of symptoms was compared with the symptoms before intervention. Data were analyzed using SPSS software (version 20), and Independent t-test, Mann-Whitney, Chi-square and covariance analysis. PResults: In the intervention group, means score of behavioral (P<0.001), physical (P=0.007), and psychological symptoms (P=0.003) and total symptoms (P<0.001) significantly decreased after the intervention compared with before the intervention. Conclusion: Dried black seed grape with no adverse effect can be effective on reducing symptoms of premenstrual syndrome. © 2016 - Journal Management System. Created bysinaweb.


Nikkhah P.,Ahvaz Jundi Shapour University of Medical science | Abedi P.,Ahvaz Jundi Shapour University of Medical science | Najjar S.,Ahvaz Jundi Shapour University of Medical science
Iranian Journal of Obstetrics, Gynecology and Infertility | Year: 2015

Introduction: Menopause is effective on women’s general health and quality of life. Since so far, no study is performed in Iran about the effect of continued walking on general health in the postmenopausal women, the present study was performed with aim to determine the effect of regular walking with pedometer on general health in the postmenopausal women at medical-health centers of Ahvaz. Methods: This randomized clinical trial was performed on 106 qualified postmenopausal at women medical-health centers in east and west of Ahvaz in 2014. The subjects were randomly placed in two groups of intervention and control. The intervention group had walking at least three times a week, each time for half an hour, and their steps were recorded with a pedometer. The data were collected using Goldberg’s General Health Questionnaire-28 (GHQ-28) and Demographic Questionnaire when GHQ was used in four stages (before intervention, four weeks, eight weeks, and twelve weeks later). Data was analyzed using SPSS software (version 19) and Kolmogorov-Smirnov test, t, Mann-Whitney, chi-square, and repeated measures. PResults: Mean general health in the intervention group at the beginning and end of the study were 25±7.7 and 19.4±4.7, respectively (P=0.001), and in the control group, 22.7±7.7 and 24±5, respectively (P=0.85). Mean physical symptoms in the intervention group at the beginning and end of the study were 6.7±2.3 and 5.80±1.6, respectively (P<0.001), and in the control group, 6.4±2.8 and 7.3±2.3, respectively (P=0.86). Mean anxiety and insomnia in the intervention group at the beginning and end of the study were 7.8±3.8 and 4.2±2.8, respectively (P=0.002), and in the control group, 6.8±3.3 and 7.2±2.5, respectively (P=0.8). Mean social function in the intervention group at the beginning and end of the study were 7.7±3.1 and 8.4±1.9, respectively (P=0.5), and in the control group, 7.5±2.5 and 6.7±1.5, respectively (P=0.58). Mean depression in the intervention group at the beginning and end of the study were 2.8±3.3 and 1.6±2, respectively (P=0.02), and in the control group, 1.8±2.2 and 3.1±1.6, respectively (P=0.2). Conclusion: Regular walking in menopausal women maintains physical and psychological health and promotes their general health. Therefore, according to the results of the study and the access to supportive sources in health system, the necessity of holding the training sessions about physical activity and walking at health centers becomes much more evident. © 2015 Mashhad University of Medical Sciences. All rights Received.


Shamakhteh K.,Ahvaz Jundi Shapour University of Medical science | Javad Nouri M.,Ahvaz Jundi Shapour University of Medical science | Jafarideh Y.,Ahvaz Jundi Shapour University of Medical science | Saki A.,Ahvaz Jundi Shapour University of Medical science
Iranian Journal of Obstetrics, Gynecology and Infertility | Year: 2016

Introduction: Toxoplasmosis during pregnancy has some clinical complications including spontaneouse abortions,preterm labor,still birth and fetal anomaly. Since premature rupture of membrane (PROM) is the major factor in preterm labor (PTL),this study was performed with aim to determine the relationship between premature rupture of membrane and toxoplasma gondii infection in pregnant women. Methods: This case-control study was carried out on 150 pregnant women referred to Ahwaz Emam Khomeini hospital for delivery in 2016. 50 pregnant women with preterm labor and premature rupture of membranes were selected as case group and 100 pregnant women with preterm labor and healthy membranes (after completing the questionnaire and examination) were selected as control group. Anti Toxoplasma IgG and IgM antibody was measuresd by ELISA in two groups. Analysis of data was performed by statistical software SPSS (version 21) and Chi-square,logistic regression,independent t-test and Mann-Whitney test. PResults: In women with preterm labor and without rupture of membranes,51% were positive for Toxoplasma IgG antibody and 3% for Toxoplasma IgM antibody. The above value was 42% in pregnant women with PTL and 4% in pregnant women with PROM. Chi-square test showed no significant difference between rupture of membranes and Toxoplasmosis (P>0.05). Conclusion: This study showed no relationship between Toxoplasma gondii and PROM. Therefore,the effect of toxoplasmosis in PROM is possibly related to other mechanisms rather than PROM. © 2016,Mashhad University of Medical Sciences. All rights reserved.

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