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Patent
Agios Pharmaceuticals | Date: 2016-10-28

Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.


Patent
Agios Pharmaceuticals | Date: 2016-08-04

Provided are compounds useful for treating cancer and methods of making the compounds and intermediates described herein.


Patent
Agios Pharmaceuticals | Date: 2016-11-09

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.


Patent
Agios Pharmaceuticals | Date: 2016-08-16

Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2).


Patent
Agios Pharmaceuticals | Date: 2016-03-24

Compounds and compositions comprising compounds that activate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that activate PKM2 in the treatment of cancer.


Patent
Agios Pharmaceuticals | Date: 2016-09-20

The invention described herein features methods, compositions, and kits that utilize activators of pyruvate kinase M2 (PKM2) for the treatment or amelioration of disorders related to PKM2 function and characterized by abnormally low levels of serine.


Patent
Agios Pharmaceuticals | Date: 2016-01-05

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.


Patent
Agios Pharmaceuticals | Date: 2016-09-28

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.


Patent
Agios Pharmaceuticals | Date: 2016-04-07

Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.


Patent
Agios Pharmaceuticals | Date: 2016-06-29

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.

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