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Santa Clara, CA, United States

Agilent Technologies, or Agilent, is an American company that designs and manufactures measurement instruments and equipment for life science, medical diagnostics, and chemistry applications.Agilent's predecessor company was Hewlett-Packard , founded in 1939 to make electronic test equipment. In 1999, HP spun-off their test and measurement division as Agilent. The resulting IPO of Agilent stock may have been the largest in the history of Silicon Valley at the time. In 2014, Agilent spun-off its electronics instruments division into Keysight Technologies.Agilent maintains a central research and development group, Agilent Laboratories, that conducts the company's research in such areas as microelectromechanical systems, nanotechnology, and life science. This centralized group is based on the original Hewlett-Packard Lab's design and was formed by dividing the original HP Labs group into two when Agilent was carved out of HP in 1999. Wikipedia.

Helfman J.,Agilent Technologies
Information Visualization | Year: 2011

An eye tracking methodology can help uncover subtle cognitive processing stages that are otherwise difficult to observe in visualization evaluation studies. Pros and cons of eye tracking methods are discussed here, including common analysis metrics. One example metric is the initial time at which all elements of a visualization that are required to complete a task have been viewed. An illustrative eye tracking study was conducted to compare how radial and linear graphs support value lookup tasks for both one and two data-dimensions. Linear and radial versions of bar, line, area, and scatter graphs were presented to 32 participants, who each completed a counterbalanced series of tasks. Tasks were completed more quickly on linear graphs than on those with a radial layout. Scanpath analysis revealed that a three-stage processing model was supported: (1) find desired data dimension, (2) find its datapoint, and (3) map the datapoint to its value. Mapping a datapoint to its value was slower on radial than linear graphs, probably because eyes need to follow a circular, as opposed to a linear path. Finding a datapoint within a dimension was harder using line and area graphs than bar and scatter graphs, possibly due to visual confusion of the line representing a data series. Although few errors were made, eye tracking was also used here to classify error strategies. As a result of these analyses, guidelines are proposed for the design of radial and linear graphs. © The Author(s) 2011.

Skarzynski T.,Agilent Technologies
Acta Crystallographica Section D: Biological Crystallography | Year: 2013

While the majority of macromolecular X-ray data are currently collected using highly efficient beamlines at an ever-increasing number of synchrotrons, there is still a need for high-performance reliable systems for in-house experiments. In addition to crystal screening and optimization of data-collection parameters before a synchrotron trip, the home system allows the collection of data as soon as the crystals are produced to obtain the solution of novel structures, especially by the molecular-replacement method, and is invaluable in achieving the quick turnover that is often required for ligand-binding studies in the pharmaceutical industry. There has been a continuous evolution of X-ray sources, detectors and software developed for in-house use in recent years and a diverse range of tools for structural biology laboratories are available. An overview of the main directions of these developments and examples of specific solutions available to the macromolecular crystallography community are presented in this paper, showing that data collection 'at home' is still an attractive proposition complementing the use of synchrotron beamlines.

Kincaid R.,Agilent Technologies
IEEE Transactions on Visualization and Computer Graphics | Year: 2010

Electronic test and measurement systems are becoming increasingly sophisticated in order to match the increased complexity and ultra-high speed of the devices under test. A key feature in many such instruments is a vastly increased capacity for storage of digital signals. Storage of 109 time points or more is now possible. At the same time, the typical screens on such measurement devices are relatively small. Therefore, these instruments can only render an extremely small fraction of the complete signal at any time. SignalLens uses a Focus+Context approach to provide a means of navigating to and inspecting low-level signal details in the context of the entire signal trace. This approach provides a compact visualization suitable for embedding into the small displays typically provided by electronic measurement instruments. We further augment this display with computed tracks which display time-aligned computed properties of the signal. By combining and filtering these computed tracks it is possible to easily and quickly find computationally detected features in the data which are often obscured by the visual compression required to render the large data sets on a small screen. Further, these tracks can be viewed in the context of the entire signal trace as well as visible high-level signal features. Several examples using real-world electronic measurement data are presented, which demonstrate typical use cases and the effectiveness of the design. © 2006 IEEE.

Kupce E.,Agilent Technologies
Topics in current chemistry | Year: 2013

Parallel acquisition NMR spectroscopy (PANSY) is used to detect simultaneously signals from up to four nuclear species, such as H-1, H-2, C-13, N-15, F-19 and P-31. The conventional COSY, TOCSY, HSQC, HMQC and HMBC pulse sequences have been adapted for such applications. Routine availability of NMR systems that incorporate multiple receivers has led to development of new types of NMR experiments. One such scheme named PANACEA allows unambiguous structure determination of small organic molecules from a single measurement and includes an internal field/frequency correction routine. It does not require the conventional NMR lock system and can be recorded in pure liquids. Furthermore, long-range spin-spin couplings can be extracted from the PANACEA spectra and used for three-dimensional structure refinement. In bio-molecular NMR, multi-receiver NMR systems are used for simultaneous recording of H-1 and C-13 detected multi-dimensional spectra. For instance, the 2D (HA)CACO and 3D (HA)CA(CO)NNH experiments can be recorded simultaneously in proteins of moderate size (up to 30 kDa). The multi-receiver experiments can also be used in combination with the fast acquisition schemes such as Hadamard spectroscopy, computer optimized aliasing and projection-reconstruction techniques. In general, experiments that utilize multiple receivers provide significantly more information from a single NMR measurement as compared to the conventional single receiver techniques.

Agency: GTR | Branch: EPSRC | Program: | Phase: Training Grant | Award Amount: 4.28M | Year: 2014

Condensed matter physics is a major underpinning area of science and technology. For example, the physics of electrons in solids underpins much of modern technology and will continue to do so for the foreseeable future. We propose to create a Centre for Doctoral Training (CDT) which will address the national need to develop researchers equipped with the skill sets and perspective to make worldwide impact in this area. The research themes covered address some very fundamental questions in science such as the physics of superconductors, novel magnetic materials, single atomic layer crystals, plasmonic structures, and metamaterials, and also more applied topics in the power electronics, optoelectronics and sensor development fields. There are strong connections between fundamental and applied condensed matter physics. The goal of the Centre is to provide high calibre graduates with a focussed but comprehensive training programme in the most important physical aspects of these important materials, from intelligent design (first principles electronic structure calculations and modelling), via cutting-edge materials synthesis, characterisation and sophisticated instrumentation, through to identification and realisation of exciting new applications. In addition programme development will emphasise transferable skills including business & enterprise, outreach and communication. As stated in the impact section, physics-dependent businesses are of major importance to the UK economy.

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