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Molina-Arrebola M.A.,Agencia Publica Empresarial Sanitaria Hospital de Poniente | Sanchez-Crespo A.,Agencia Publica Empresarial Sanitaria Hospital de Poniente | Garcia-Martin P.,Agencia Publica Empresarial Sanitaria Hospital de Poniente | Perez-Moyano R.,Agencia Publica Empresarial Sanitaria Hospital de Poniente | And 2 more authors.
Revista del Laboratorio Clinico | Year: 2014

Haemoglobinopathies are the most frequent monogenic disorders, particularly in certain races and areas, because of their protective effect against malaria. Migratory changes are leading to an increase in these conditions in the western world. High Performance Liquid Chromotography (HPLC) is nowadays a method of choice in detecting structural haemoglobinopathies and in the quantification of foetal and haemoglobin (Hb) A2. A clinical case is described in which a double heterozygous HbO-Arab and α-thalassaemia was identified following the detection of microcytosis and an anomalous haemoglobin variant, which was lower than expected - highlighting the appropriateness of a multidisciplinary study for these types of pathologies. © 2014 AEBM, AEFA y SEQC. Source

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