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PubMed | Agence Regionale de Sante Nord Pas de Calais, Lille University of Science and Technology and Lille University Hospital Center
Type: | Journal: Age and ageing | Year: 2017

potentially inappropriate medication (PIM) prescribing is common in older people and leads to adverse events and hospital admissions.to determine whether prevalence of PIM prescribing varies according to healthcare supply and socioeconomic status.all prescriptions dispensed at community pharmacies for patients aged 75 and older between 1 January and 31 March 2012 were retrieved from French Health Insurance Information System of the Nord-Pas-de-Calais Region for patients affiliated to the Social Security scheme. PIM was defined according to the French list of Laroche. The geographic distribution of PIM prescribing in this area was analysed using spatial scan statistics.overall, 65.6% (n = 207,979) of people aged 75 years and over living in the Nord-Pas-de-Calais Region were included. Among them, 32.6% (n = 67,863) received at least one PIM. The spatial analysis identified 16 and 10 clusters of municipalities with a high and a low prevalence of PIM prescribing, respectively. Municipalities with a low prevalence of PIM were characterised by a high socioeconomic status whereas those with a high prevalence of PIM were mainly characterised by a low socioeconomic status, such as a high unemployment rate and low household incomes. Markers of healthcare supply were weakly associated with high or low prevalence clusters.significant geographic variation in PIM prescribing was observed in the study territory and was mainly associated with socioeconomic factors.


Jean-Baptiste B.,University Hospital of Lille | Jean-Baptiste B.,Lille 2 University of Health and Law | Corinne D.,Agence Regionale de Sante Nord Pas de Calais | Marie-Margueritte D.,Agence Regionale de Sante Nord Pas de Calais | Francois P.,University Hospital of Lille
Archives of Gerontology and Geriatrics | Year: 2014

Prescriptions of PIMs and anticholinergic drugs lead to adverse events and hospitalizations in the elderly. The objective of this study was to determine the prevalence of PIMs and prescriptions with a high anticholinergic effect in a French region. All prescriptions dispensed at community pharmacies in patients aged 75 and older between January 1 and March 31, 2012 were extracted from French Health Insurance information System - Nord-Pas-de-Calais Region for patients affiliated to the Social Security. Prescription of PIMs was defined according to the Laroche list. The anticholinergic score for each prescription was calculated using the Anticholinergic Drug Scale (ADS). 65.6% (n = 207,979) of people aged over 75 years, living in the Nord-Pas-de-Calais Region were included, of which 4.5% (n = 9284) living in nursing homes. Patients received an average of 8.3 drugs over the 3-month study period. In 32.6% (n = 67,863) of patients, at least one PMI was prescribed. According to the ADS, 10.0% (n = 20,978) of patients in the general population and 24.0% (n = 2231) of patients living in nursing homes was exposed to a prescription with a high or very high anticholinergic score (ADS. ≥. 3). Hydroxyzine prescribed in 51.4% (n = 10,792) of them ranked first among drugs most often reported. In conclusion, PMIs and anticholinergic drugs were commonly prescribed in elderly living in the Nord-Pas-de-Calais Region. Improving the quality of prescriptions in the elderly appears necessary. © 2014 Elsevier Ireland Ltd.


PubMed | Agence Regionale de Sante Nord Pas de Calais, University Hospital of Lille and Lille 2 University of Health and Law
Type: Journal Article | Journal: Archives of gerontology and geriatrics | Year: 2014

Prescriptions of PIMs and anticholinergic drugs lead to adverse events and hospitalizations in the elderly. The objective of this study was to determine the prevalence of PIMs and prescriptions with a high anticholinergic effect in a French region. All prescriptions dispensed at community pharmacies in patients aged 75 and older between January 1 and March 31, 2012 were extracted from French Health Insurance information System - Nord-Pas-de-Calais Region for patients affiliated to the Social Security. Prescription of PIMs was defined according to the Laroche list. The anticholinergic score for each prescription was calculated using the Anticholinergic Drug Scale (ADS). 65.6% (n=207,979) of people aged over 75 years, living in the Nord-Pas-de-Calais Region were included, of which 4.5% (n=9284) living in nursing homes. Patients received an average of 8.3 drugs over the 3-month study period. In 32.6% (n=67,863) of patients, at least one PMI was prescribed. According to the ADS, 10.0% (n=20,978) of patients in the general population and 24.0% (n=2231) of patients living in nursing homes was exposed to a prescription with a high or very high anticholinergic score (ADS3). Hydroxyzine prescribed in 51.4% (n=10,792) of them ranked first among drugs most often reported. In conclusion, PMIs and anticholinergic drugs were commonly prescribed in elderly living in the Nord-Pas-de-Calais Region. Improving the quality of prescriptions in the elderly appears necessary.

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