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Grant
Agency: Cordis | Branch: FP7 | Program: CP-TP | Phase: KBBE.2013.1.3-02 | Award Amount: 7.76M | Year: 2014

Global apiculture is facing an unprecedented crisis of increasing parasite pressure and a loss of hon-eybee biodiversity. SMARTBEES unites a team of experts with the necessary skills to build a bright and sustainable future. The SMARTBEES concept is low risk and high impact, using established protocols and state-of-the-art methods. Including world leading researchers from outwith the traditional honeybee sphere (e.g. acarology, genetic breeding and insect immunology). We will identify crucial facets of honeybee resistance to colony losses, Varroa and viruses. We will provide a step-change in the current mechanistic understanding of these traits, and will characterise the genetic background of the resistance mechanisms in honeybees. We will develop breeding strategies to increase the frequencies of these valuable traits in local honeybee populations, considering the variable need of both common and endangered subspecies and local beekeeping practises. Breeding efforts concentrating on very few races may endanger genetic diversity, to avoid this SMARTBEES will promote multiple local breeding efforts, to conserve local resilient populations and will develop molecular tools for describing and safeguarding future populations. SMARTBEES recognizes responsibility to protect our natural honeybee heritage. SMARTBEES will commission extension science, and work in cooperation with stakeholders to attain conservation by utilisation. SMARTBEES will establish a network of apiaries for performance testing, to encourage local uptake of resistant traits. These will be run mainly by beekeepers, thereby improving the local acceptability and dissemination, and support the long-term sustainability of the apicultural sector. SMARTBEES recognises the need to horizon scan for new threats, and the consortium includes the current EU reference laboratory to that end. SMARTBEES is an opportunity to make a lasting difference to the health, resilience and genetic diversity of our honeybees.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: SFS-12-2014 | Award Amount: 8.82M | Year: 2015

Euromix aim to develop an experimentally verified, tiered strategy for the risk assessment of mixtures of multiple chemicals derived from multiple sources across different life stages. The project takes account of the gender dimension and balances the risk of chemicals present in foods against the benefits of those foods. Important concepts for this new strategy are prioritisation criteria for chemicals based on their exposure and hazard characteristics and evaluation of the role of mode of action in grouping chemicals into cumulative assessment groups. In-silico and in-vitro tools will be developed and verified against in-vivo experiments, with focus on four selected endpoints (liver, hormones, development and immunology) to provide a full proof-of-principle. The EuroMix project will result in an innovative platform of bioassays for mixture testing and refined categorisation of chemicals in cumulative assessment groups. New hazard and exposure models will be embedded in a model toolbox, made available for stakeholders through an openly accessible web-based platform. Access to the web-based tools will be facilitated by training. Criteria will be set and guidance will be written on how to use and implement the tiered test strategy. Dissemination and harmonisation of the approach within EU, Codex Alimentarius, and WHO will be achieved by involving a.o. WHO and US-EPA in the project and by the participation of experts playing a key role in helping establish international food safety policies. It is expected that the new mechanism-based strategy, the bioassay platform, the openly accessible web-based model toolbox, and clear guidance on a tiered hazard and exposure test and risk assessment strategy will boost innovation in the public and private sector, provide a sound scientific basis for managing risks to public health from chemical mixtures, ultimately reduce the use of laboratory animals, and support the global discussion of risk assessment policies for mixtures.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: SFS-19-2014 | Award Amount: 5.30M | Year: 2015

Strengthening food and nutrition security (FNS) in the EU requires a move towards a diet that supports sustainable food consumption and production. To gauge the policy reforms needed for this major societal challenge, the SUSFANS-consortium will identify how food production and nutritional health in the EU can be aligned. The multidisciplinary research agenda of SUSFANS will build the conceptual framework, the evidence base and analytical tools for underpinning EU-wide food policies with respect to their impact on consumer diet and their implications for nutrition and public health, the environment, the competitiveness of the EU agri-food sectors, and global FNS. Based on a conceptual model of the food chain and its stakeholders, SUSFANS will develop suitable metrics and identify major drivers for sustainable FNS, integrate data and modelling, and develop foresight for European sustainable FNS. Central asset is a coherent toolbox which integrates two complementary strands of state-of-the-art quantitative analysis: (i) micro-level modelling of nutrient intakes, habitual dietary patterns and preferences of individual consumers, and (ii) macro-level modelling of food demand and supply in the context of economic, environmental and demographic changes on various time-scales and for multiple sub-regions. The tools will bridge the current gap between policy analysis on the EU agri-food sector and the nutrition-health sector. Case studies and scenarios based on stakeholder input from consumers, food industry, farmers/fishermen, government and the scientific community, are instrumental in achieving this goal. The project will provide a comprehensive set of tools for assessing sustainable FNS in Europe, centred around the implications of the current diet for the sustainability of production and consumption in the EU, and the options for the EU agri-food sector (including fisheries and aquaculture) to improve future diets in the near future (up to 5 years) and in the long run (one or more decades ahead).


Grant
Agency: Cordis | Branch: FP7 | Program: BSG-SME-AG | Phase: SME-2013-2 | Award Amount: 2.69M | Year: 2013

Campylobacteriosis is the most frequently reported zoonotic illness at the EU in 2011, with 9 million human cases, and a total annual cost of 2.4 billion per year in the EU27. Poultry meat is the major single source of human infection. Recent studies have shown that European broiler flocks have a high prevalence of Campylobacter colonization with an average of 71%. However, there is still no effective, reliable and practical strategy available to prevent or to reduce Campylobacter colonization in broilers. The objective of the present project is to develop a two-steps strategy in order to fight against Campylobacter in primary poultry production: first step nutritional approach, through the use of a synergic combination of different products such as plant extracts (PE), organic acids (OA), prebiotics (PRE), probiotics (PRO), and feed presentation (FP) through 4 work packages (WPs) in which trials with infected broilers and in experimental and real conditions will be done. In a second step, vaccination approach based on a novel development of a Campylobacter vaccine through the use of reverse vaccinology. The expected results of the project will be a short term strategy through new nutritional strategies based on a synergic combination of feed products and feed presentation and a medium term strategy through a novel vaccine to reduce the prevalence of Campylobacter in broiler flocks. The consortium is formed by five National poultry producers SME-AGs (PROPOLLO, FIA, CIDEF, NEPLUVI and BTT), two RTD (ANSES, and IMASDE) and three SMEs (MIKROLAB, REDONDO, and CZV).


Grant
Agency: Cordis | Branch: FP7 | Program: CP-TP | Phase: KBBE.2012.2.4-02 | Award Amount: 5.06M | Year: 2013

Despite many efforts to ensure that only high-quality and safe products are put on the market, fish-borne parasites continue to pose risks to human health, with zoonotic infections and allergic reactions mainly following consumption of raw, lightly cooked, or marinated seafood. The PARASITE proposal is presented by a multidisciplinary consortium of 12 European and 3 Asian research institutions and 6 European SMEs. It aims to provide new scientific evidence and technological developments to detect, monitor, and mitigate impacts of zoonotic parasites, mainly anisakid nematodes but also trematode metacercariae, occurring in European and imported fishery products. The Project will address the research needs identified by EFSA regarding the risk of seafood-borne parasites. It also will facilitate close cooperation between scientists and end-users to produce new technological solutions and management tools for both European and imported fishery products. The Work Plan has been organized in 9 work packages, each covering different stages of a risk assessment framework, providing new epidemiological data, monitoring tools, development and implementation of parasite detection devices, technological tools for their mitigation, and dissemination of key results to all the stakeholders and the general public. Risk assessment of zoonotic parasites will ensure significant progress beyond the state of the art. This will be achieved by improving molecular hazard identification, antigen/allergen characterization, parasite exposure assessment, detection methods and treatments for industrial and other end-users, and an integrated quantitative risk analysis based on powerful statistics and modelling, The main results will impact by (1) contributing to enhanced seafood safety, with consequent benefits for public health and consumer confidence, (2) strengthening the competitiveness of European seafood, from the net to the plate and (3) improving EU food safety policies.

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