Affiliated Hospital of Armed Police Logistics Institute

Tianjin, China

Affiliated Hospital of Armed Police Logistics Institute

Tianjin, China
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Xiong J.,Affiliated Hospital of Armed Police Logistics Institute | Ning L.-N.,Affiliated Hospital of Armed Police Logistics Institute | Wang Z.-L.,Affiliated Hospital of Armed Police Logistics Institute | Shi X.-M.,Tianjin University of Traditional Chinese Medicine
Chinese Journal of Tissue Engineering Research | Year: 2013

BACKGROUND: Although the incidence of neurodegenerative diseases in various populations is high and has an upward trend, so far there is no effective treatment method. So it is a challenge for scientific community to seek effective treatment method for the treatment of neurodegenerative diseases. OBJECTIVE: To analyze and review the research progress and hot issues of stem cells for the treatment of neurodegenerative diseases. METHODS: The basic and clinical researches on stem cells for the treatment of neurodegenerative diseases were overviewed, including Alzheimer's disease, Parkinson's disease, stroke, Huntington's disease, retinitis pigmentosa, amyotrophic lateral sclerosis and epilepsy, in order to investigate the feasibility, advantages and problems of stem cells in the treatment of neurodegenerative diseases. ESULTS AND CONCLUSION: Most of the studies on stem cells in the treatment of neurodegenerative diseases are in the stage of experimental animal models, and there is no valid evidence to support stem cell therapy. There is no exact clinical assurance and standards on the safety and efficacy of stem cells for the treatment of neurodegenerative diseases, and the clinical efficacy and adverse reactions need to be further verified with large-sample long-term clinical trials.

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