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Hawthorne, CA, United States

Nakamura R.K.,Advanced Veterinary Care Center
Compendium (Yardley, PA) | Year: 2012

Nosocomial infections (NIs) are infections acquired during hospitalization. They are characterized by a high incidence of antimicrobial resistance. The most common NIs are pneumonia and urinary tract, surgical site, and bloodstream infections. Hand hygiene has demonstrated efficacy in reducing NIs.

Song R.B.,University of Pennsylvania | Vite C.H.,University of Pennsylvania | Bradley C.W.,University of Pennsylvania | Cross J.R.,University of Pennsylvania | Cross J.R.,Advanced Veterinary Care Center
Journal of Veterinary Internal Medicine | Year: 2013

Background: Intracranial neoplasia of dogs is frequently encountered in veterinary medicine, but large-scale studies on prevalence are lacking. Objectives: To determine the prevalence of intracranial neoplasia in a large population of dogs examined postmortem and the relationship between breed, age, and weight with the presence of primary intracranial neoplasms. Animals: All dogs that underwent postmortem examination from 1986 through 2010 (n = 9,574), including dogs with a histopathologic diagnosis of primary (n = 227) and secondary (n = 208) intracranial neoplasia. Methods: Retrospective evaluation of medical records from 1986 through 2010. Results: Overall prevalence of intracranial neoplasia in this study's population of dogs was 4.5%. A statistically significant higher prevalence of primary intracranial neoplasms was found in dogs with increasing age and body weights. Dogs ≥15 kg had an increased risk of meningioma (odds ratio 2.3) when compared to dogs <15 kg. The Boxer, Boston Terrier, Golden Retriever, French Bulldog, and Rat Terrier had a significantly increased risk of primary intracranial neoplasms while the Cocker Spaniel and Doberman Pinscher showed a significantly decreased risk of primary intracranial neoplasms. Conclusions and Clinical Importance: Intracranial neoplasia in dogs might be more common than previous estimates. The study suggests that primary intracranial neoplasia should be a strong differential in older and larger breed dogs presenting with signs of nontraumatic intracranial disease. Specific breeds have been identified with an increased risk, and others with a decreased risk of primary intracranial neoplasms. The results warrant future investigations into the role of age, size, genetics, and breed on the development of intracranial neoplasms. © 2013 by the American College of Veterinary Internal Medicine.

Nakamura R.K.,Advanced Veterinary Care Center
Compendium (Yardley, PA) | Year: 2012

Methicillin-resistant Staphylococcus aureus infection is currently the most common skin infection identified in human emergency rooms, and the development of methicillin resistance is increasing in veterinary medicine. This article reviews the current knowledge about methicillin-resistant Staphylococcus infections in human medicine as well as the limited information available in veterinary medicine, including options for diagnosis, treatment, and prevention.

Ghaffari S.,VCA West Los Angeles Animal Hospital | Pelio D.C.,Advanced Veterinary Care Center | Lange A.J.,Advanced Veterinary Care Center | Arndt J.W.,Advanced Critical Care of Los Angeles | And 4 more authors.
Journal of Small Animal Practice | Year: 2014

OBJECTIVE: To report the outcome of doxorubicin-based chemotherapy as the sole treatment for dogs with echocardiographically identified right atrial masses and pericardial effusion. METHODS: A retrospective study of case records of dogs with right atrial masses treated with doxorubicin. Dogs were excluded from the study if they had any type of surgery performed such as pericardiectomy or right atrial mass resection, or if their chemotherapy protocol did not include doxorubicin. The data collected included signalment, history, physical examination findings, diagnostic test results and long-term survival. RESULTS: Dogs with right atrial masses and pericardial effusion that received doxorubicin-based chemotherapy alone had a median survival of 139·5 days (range 2 to 302 days). Chemotherapy side effects were frequent but mild. CLINICAL SIGNIFICANCE: Doxorubicin-based chemotherapy alone appears to be a viable treatment option for dogs with echocardiographically identified right atrial masses and pericardial effusion. © 2014 British Small Animal Veterinary Association.

Murphy L.A.,Oradell Animal Hospital | Russell N.J.,Advanced Veterinary Care Center | Dulake M.I.,VCA West Los Angeles Animal Hospital | Nakamura R.K.,Veterinary Medical Surgical Group Orange County
Journal of Feline Medicine and Surgery | Year: 2014

A 4-year-old female spayed domestic longhair cat was referred for dyspnea. Further diagnostics revealed severe pleural effusion and a peritoneopericardial diaphragmatic hernia (PPDH). Following surgical correction of the PPDH the pleural effusion persisted. Re-check echocardiogram 4 weeks after initial evaluation revealed leftward deviation of the interventricular septum and interatrial septum occurring with inspiration. There were also exaggerated phasic changes in trans-tricuspid flow velocities suggestive of constrictive pericardial disease. Cardiac catheterization was performed and revealed elevated pressures in the right atrium and right ventricle. Constrictive pericarditis (CP) and epicarditis was confirmed at surgery, where subtotal pericardiectomy was performed with epicardial decortication. The cat continued to develop recurrent pleural effusion after surgery, although the volume and frequency of recurrence slowed over time. This is the first reported case of CP following PPDH repair in a cat. © ISFM and AAFP 2014.

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