Ly S.,Seoul National University of Science and Technology |
Kim N.J.,Seoul National University of Science and Technology |
Youn M.,Advanced Scientific Research Group |
Kim Y.,Advanced Scientific Research Group |
And 3 more authors.
Toxicological Research | Year: 2013
A method of detecting lead was developed using square wave anodic stripping voltammetry (SWASV) with DNA-carbon nanotube paste electrode (CNTPE). The results indicated a sensitive oxidation peak current of lead on the DNA-CNTPE. The curves were obtained within a concentration range of 50 ngL-1- 20 mgL-1 with preconcentration time of 100, 200, and 400 sec at the concentration of mgL-1, μgL-1, and ngL-1, respectively. The observed relative standard deviation was 0.101% (n = 12) in the lead concentration of 30.0 μgL-1 under optimum conditions. The low detection limit (S/N) was pegged at 8 ngL-1 (2.6 × 10-8 M). Results showed that the developed method can be used in real-time assay in vivo without requiring any pretreatment and pharmaceutical samples, and food samples, as well as other materials requiring water source contamination analyses.