Gorgulu O.,Adana Numune Education and Research Hospital Adana |
Ozelci M.,Adana Numune Education and Research Hospital Adana |
Ozdemir S.,Cukurova University |
Yasar M.,Adana Numune Education and Research Hospital Adana |
And 2 more authors.
Journal of International Advanced Otology | Year: 2012
Objective: The etiological role of allergy in the pathogenesis of chronic suppurative otitis media (CSOM) has not been clearly shown. The aim of this study was to assess the role of allergy in the etiology of CSOM. Materials and Methods: In this study, total and allergen specific IgE levels, as well as blood eosinophil counts of 61 consecutive patients with CSOM and 31 healthy controls were measured. Endoscopic evaluations of the rhinopharynx were done in both groups. Results: The difference in mean total serum IgE levels and blood eosinophil counts between patients with CSOM and healthy controls were statistically insignificant (p=0,611, p=0,804 consecutively). More patients with CSOM had serum total IgE levels greater than 300 IU/ml compared to healthy controls, and this difference was statistically significant (p=0,031). Positivity rates against any of the allergens were higher in the CSOM patient group compared to healthy control. The difference between two groups was statistically significant (p=0,042). Evaluation of allergen-specific IgE levels found in the Turkish Mixed 20 respiratory allergy panel only revealed a significant difference between patients with CSOM and healthy controls with regards to allergy against house dust mites (pterony and farinae)(p=0,037 for two values). Conclusion: The present study shows that some of our results support a role of allergy in the etiology of CSOM. Thus, the possibility of allergy should be considered in CSOM patients preoperatively, the drug treatment of allergy might be helpful in addition to the operational treatment of CSOM patients in case of allergy. © 2005 The Mediterranean Society of Otology and Audiology. Source