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Jimenez-Gonzalez C.,Glaxosmithkline | Poechlauer P.,DSM Pharmaceutical Products | Broxterman Q.B.,Royal DSM | Yang B.-S.,Boehringer Ingelheim Pharmaceuticals | And 11 more authors.
Organic Process Research and Development | Year: 2011

In 2005, the American Chemical Society (ACS) Green Chemistry Institute (GCI) and global pharmaceutical companies established the ACS GCI Pharmaceutical Roundtable to encourage the integration of green chemistry and engineering into the pharmaceutical industry. The Roundtable developed a list of key research areas in green chemistry in 2007, which has served as a guide for focusing green chemistry research. Following that publication, the Roundtable companies have identified a list of the key green engineering research areas that is intended to be the required companion of the first list. This publication summarizes the process used to identify and agree on the top key green engineering research areas and describes these areas, highlighting their research challenges and opportunities for improvements from the perspective of the pharmaceutical industry. © 2011 American Chemical Society.


Poechlauer P.,Royal DSM | Colberg J.,Pfizer | Fisher E.,Merck And Co. | Jansen M.,Hoffmann-La Roche | And 7 more authors.
Organic Process Research and Development | Year: 2013

The American Chemical Society (ACS) Green Chemistry Institute (GCI) Pharmaceutical Roundtable conducted a study to elucidate the value of continuous processing, which had been defined as a key research area for green engineering. In the course of defining the business case for continuous processing, individual cases were collected and evaluated to determine specific drivers to implement continuous processing and to find key success factors. The magnitude and timing of effects and the relation to the principles of green chemistry were investigated. © 2013 American Chemical Society.


Jimenez-Gonzalez C.,Glaxosmithkline | Ponder C.S.,Glaxosmithkline | Broxterman Q.B.,Royal DSM | Manley J.B.,ACS Green Chemistry Institute
Organic Process Research and Development | Year: 2011

There have been a many publications and much discussion about green metrics. While many have been proposed, The American Chemical Society Green Chemistry Institute's Pharmaceutical Roundtable has chosen process mass intensity (PMI) as the key, high-level metric for evaluating and benchmarking progress towards more sustainable manufacturing. This paper provides the philosophical and technical arguments on why PMI was chosen above other related metrics such as E factor or atom economy. © 2011 American Chemical Society.


Poechlauer P.,Royal DSM | Manley J.,ACS Green Chemistry Institute | Broxterman R.,Royal DSM | Gregertsen B.,Astrazeneca | Ridemark M.,Astrazeneca
Organic Process Research and Development | Year: 2012

Continuous manufacturing as a way of producing fine chemicals, active pharmaceutical ingredients, and finished dosage forms is gaining widespread attention. Although potential benefits over traditional batch-wise production have been discussed at many occasions and appear evident, continuous processes are only slowly being implemented. The American Chemical Society Green Chemistry Institute Pharmaceutical Roundtable has defined "continuous processing" as one of its research priorities1 and performed a survey of its members' opinions, the status of implementation, and perceived hurdles blocking implementation of continuous manufacturing processes. Here we discuss the most important results of this survey and their relation to present trends in this industry to go green". © 2012 American Chemical Society.


Comanita B.,MarketChemica Inc. | Manley J.,ACS Green Chemistry Institute
Chimica Oggi/Chemistry Today | Year: 2012

Participation in the ACS Green Chemistry Institute Industry Roundtables provides an excellent opportunity for member companies to keep abreast with the latest developments in the complex stakeholders landscape of green chemistry and green engineering while informing and influencing the policy, regulatory and legislative outcomes. The structure of the Roundtables, mimicking the vertical structure of the chemical supply chains, provides member companies with unique non-competitive collaboration opportunities such as minimizing R&D costs, learning about the needs of downstream customers or adopting best industry practices in green chemistry.


Sullivan S.,ACS Green Chemistry Institute
Chimica Oggi/Chemistry Today | Year: 2015

Brief review of advances in biopesticides and innovative green chemistry technologies recognized by the U.S. Environmental Protection Agency.


Young J.L.,ILSI Health and Environmental science Institute | Peoples R.,ACS Green Chemistry Institute
Journal of Chemical Education | Year: 2013

As a leader in green chemistry education, the ACS Green Chemistry Institute (ACS GCI) has developed resources for educators, students, and professionals. This communication summarizes one of the invited papers to the ConfChem online conference Educating the Next Generation: Green and Sustainable Chemistry, held from May 7 to June 30, 2010 and hosted by the ACS DivCHED Committee on Computers in Chemical Education (CCCE). The paper, "Educational Resources from the ACS Green Chemistry Institute," discussed May 14-20, 2010 during the conference covered the breadth of educational resources developed by ACS GCI. This communication highlights several new activities since the online conference, including a textbook, online tools and webinars, workshops, student award, and research grant. © 2013 The American Chemical Society and Division of Chemical Education, Inc.


Peoples B.,ACS Green Chemistry Institute
ACS National Meeting Book of Abstracts | Year: 2011

It has become abundantly clear that man cannot achieve a sustainable future by the linear extension of existing technologies. The logical question that follows is, "What do we do differently and how do we do it?" Green chemistry offers a proven alternative to the chemistry practiced in the last century. It is also obvious that we cannot simply and quickly abandon the huge investment in chemical manufacturing infrastructure that exists around the world. A key strategy in the transition to a new chemical manufacturing paradigm will be the growth of biobased feedstocks. This talk will lay out global challenges to sustainability, introduce the principles of green chemistry and engineering, and provide examples of the application of the principles while providing a solid return on investment and competitive advantage.

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