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Metwally M.A.,Mansoura University | Bondock S.A.,Mansoura University | El-Desouky S.I.,Mansoura University | Abdou M.M.,Academy of Scientific Research and Technology
Journal of the Korean Chemical Society | Year: 2012

Novel azopyrazolin-5-one dyes 4a-f were synthesized by the regioselective reaction of phenylhydrazine with 2,3,4-chromantrione-3-arylhydrazones 2a-f. The acid dissociation constants pKa for the series prepared were determined and correlated by the Hammett equation. The results of such correlation together with the spectral data indicated that the studied compounds exist predominantly in the hydrazone keto structure, (D) as the Z-configuration. The dyes were applied to polyester fabrics, affording orange-yellow shades and assessments of their dyeing performance are considered. Further, the compounds 4a-f were screened for their antimicrobial activity against various microorganisms. Source


Gamal-Eldeen A.M.,National Research Center of Egypt | Fouad L.M.,Academy of Scientific Research and Technology | El-Daly S.M.,National Research Center of Egypt | El-Hussieny E.A.,Ain Shams University | Denshary E.S.E.,Cairo University
Photodiagnosis and Photodynamic Therapy | Year: 2014

Background: Indocyanine green (ICG) is a promising water-soluble photosensitizer for photodynamic therapy (PDT) of tumors. It was reported to have promising phototoxic effect on different cell lines. This study aimed to evaluate the efficacy of ICG as an efficient PS agent for skin cancer induced in mice. Methods: Skin squamous cell carcinoma was induced in female CD-1 mice by 7,12-dimethylbenzanthracene and 12-. O-tetradecanoyl-phorbol-13-acetate followed by an ICG/PDT treatment. The laser irradiation for PDT was adjusted to cover the whole body of the mice to make sure that the treatment protocol will be delivered to multiple tumors. Results: The treatment of skin cancer by ICG/PDT using intravenously injected ICG initiated tumor cell death and significantly decreased cell proliferation as indicated by the reduction in proliferating cell nuclear antigen positivity. A significant reduction in the inflammatory mediators; tumor necrosis factor-α, nitric oxide and 5-lipoxygenase was reported, however the level of cyclooxygenase-2 (COX-2) was significantly elevated after ICG/PDT treatment. Conclusion: The proposed ICG/PDT treatment modality showed a significant anti-tumor and anti-inflammatory activity against skin cancer accompanied with COX-2 elevation. © 2014 Elsevier B.V. Source


Ali-Bik M.W.,National Research Center of Egypt | Metwally H.I.M.,National Research Center of Egypt | Kamel M.G.,Academy of Scientific Research and Technology | Wali A.M.A.,Cairo University
Environmental Earth Sciences | Year: 2011

Biogenic gypsum in the form of microbialite and potential domal stromatolite as well as endoevaporitic dolomite are deposited in a perennial saline basin characterized by microbial bloom. Deposition environment, mode of occurrence, and microscopic investigation including SEM of these precipitates are discussed in conjunction with XRD, XRF, and FTIR data. Combined effects of salinity gradient and the wind action on the maturity of gypsum outcrop are evident. A characteristic multi-color vertical gypsum profile reflects steep gradient of oxi-anoxic microenvironments and encodes diverse seasonal microbial communities. Direct impact of microbial signature in gypsum crystal habit is conspicuous. Endoevaporitic authigenic dolomite is recorded in specific horizons in interstices of selenite layers. © 2010 Springer-Verlag. Source


Fouad Ahmed A.A.R.M.,Academy of Scientific Research and Technology
Life Science Journal | Year: 2011

Based on corrosion action caused by stray current electrolysis, it is possible to use such concept as a new technique to destroy metallic structure of the land mines. This new technique saves a lot of money, effort and time. The idea of this new technique is to corrode the metallic material of a group of cascaded land mines at one time by the acceleration of the corrosion action. Then, the charge, the explosive material, will expose to the surrounding soil which in turn will be spoiled by humidity. Source


Marcano-Cedeno A.,Technical University of Madrid | Marcano-Cedeno A.,Biomedical Research Networking Center in Bioengineering | Wageih M.A.,Cairo University | Wageih M.A.,Academy of Scientific Research and Technology | And 3 more authors.
Studies in Health Technology and Informatics | Year: 2015

The International Medical Informatics Association (IMIA) is the world body for biomedical and health informatics (BMHI). IMIA accreditation program allows the health and medical informatics programs around the world to reach to an international level. Staffs (professors, students, education programmes directors, others) that work on the accredited BMHI programs will have the opportunity to be engaged with organizations that possess a world-class research and education profile from other countries, which will have great impacts on their field at their institutions, within their country providing the high quality overall health services. IMIA accreditation procedure is usually a long process and slightly complicated. The goal of this paper is to illustrate and to simplify the IMIA accreditation process to increase the success of the applicants. Toward more dynamic IMIA accreditation procedure, the paper presents 4 steps: translation, IMIA-Accreditation Step by Step Guideline, Questions and Answers, and finally the (new) Labelling System. © 2015 The authors and IOS Press. All rights reserved. Source

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