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Banja Luka, Bosnia and Herzegovina

Jacimovski S.K.,Academy of Criminalistic and Police Studies | Sajfert V.D.,University of Novi Sad | Rakovic D.I.,University of Belgrade | Setrajcicd J.P.,University of Novi Sad | Setrajcicd J.P.,Academy of Science and Arts of the Republic of Srpska
Digest Journal of Nanomaterials and Biostructures

We have transformed the Scott's model of protein Hamiltonian to metastable form, by means of double coherent unitary transformation. It turned out that in metastable Hamiltonian the number of quasi particles is not conserved due to the forming of pairs of excitations. The energies of pairs are found and their population is quoted. It is interesting that elementary excitations of metastable state behave similarly as excitations of molecular vibration field as well as excitations of electromagnetic field. Source

Armakovic S.,University of Novi Sad | Armakovic S.J.,University of Novi Sad | Pelemis S.,University of East Sarajevo | Mirjanic D.,University of Banja Luka | Mirjanic D.,Academy of Science and Arts of the Republic of Srpska
Physical Chemistry Chemical Physics

We investigate the influence of sumanene modifications on its adsorption properties towards the hydrogen molecule. The benzylic positions of sumanene were substituted with boron and nitrogen atoms, which changed its hydrogen storage properties. H2 binding energies were calculated using the LMP2, DFT and DFT-D3 approaches with several exchange-correlation functionals and the results indicate a physisorption mechanism. Physisorption was confirmed by fragment analysis and special attention was paid to non-covalent interactions. All non-covalent interactions, based on reduced density gradient surfaces, were identified and calculated for better understanding of the adsorption mechanism. Moreover, the significance of charge separation by inducing boron and nitrogen atoms is emphasized and special attention is paid to the z-component of the dipole moment of sumanene derivatives. © the Owner Societies. Source

Tomic M.,NanoLab, Inc. | Muncan J.,NanoLab, Inc. | Stamenkovic D.,Optix | Jokanovic M.,Academy of Science and Arts of the Republic of Srpska | Matija L.,NanoLab, Inc.
Journal of Physics: Conference Series

Since materials on nanoscale have different characteristics from materials on macro scale their biocompatibility should be precisely and specifically investigated. Fullerenes, the third carbon allotrope, are one of the most used nanomaterials. The least stable and the most common is fullerene C60. One of the main disadvantages of fullerene is its low solubility in water. In order to make it soluble, it must be functionalized with polar groups such as -OH and -COOH. From all the water soluble fullerenes the most important ones are those with -OH groups attached named fullerols. We have developed new materials for contact lenses by adding fullerene (C60) and fullerol (C 60(OH)24) into PMMA. The aim of our investigation was to compare the influences of those materials on aqueous solutions similar to tear film. For the analysis of the solutions we used opto-magnetic imaging and IR spectroscopy. The acquired spectrums were commented and compared with the standard contact lens material, which was analyzed by the same methods. The ISO 10993 cytotoxicity test on extract of nanophotonic material with incorporated C60 was done as well. This research contributes to better understanding of the biocompatibility of new rigid gas permeable contact lens materials. © IOP Publishing Ltd 2013. Source

Rakovic D.,University of Belgrade | Dugic M.,University of Kragujevac | Jeknic-Dugic J.,University of Nis | Plavsic M.,University of Belgrade | And 3 more authors.
BioMed Research International

In the context of the macroscopic quantum phenomena of the second kind, we hereby seek for a solution-in-principle of the long standing problem of the polymer folding, which was considered by Levinthal as (semi)classically intractable. To illuminate it, we applied quantum-chemical and quantum decoherence approaches to conformational transitions. Our analyses imply the existence of novel macroscopic quantum biomolecular phenomena, with biomolecular chain folding in an open environment considered as a subtle interplay between energy and conformation eigenstates of this biomolecule, governed by quantum-chemical and quantum decoherence laws. On the other hand, within an open biological cell, a system of all identical (noninteracting and dynamically noncoupled) biomolecular proteins might be considered as corresponding spatial quantum ensemble of these identical biomolecular processors, providing spatially distributed quantum solution to a single corresponding biomolecular chain folding, whose density of conformational states might be represented as Hopfield-like quantum-holographic associative neural network too (providing an equivalent global quantum-informational alternative to standard molecular-biology local biochemical approach in biomolecules and cells and higher hierarchical levels of organism, as well). © 2014 Dejan Raković et al. Source

Vulic D.,University of Banja Luka | Vulic D.,Center for Medical Research Banja Luka | Vulic D.,Academy of Science and Arts of the Republic of Srpska | Secerov-Zecevic D.,Academy of Science and Arts of the Republic of Srpska | And 3 more authors.
Current Cardiovascular Risk Reports

One of the major risk factors that may promote atherogenesis is chronic stress. War and its consequences are powerful stress factors. Wars fought all over the world have changed global life conditions. A war is a mass disaster with several effects (death, injury, loss of close persons, exposure to various tortures, home eviction, exile, rapid impoverishment, social uncertainty) that brings tremendous suffering to the population affected. Stress causes increased concentrations of catecholamine and corticosteroid hormones in blood, which may lead to atherosclerosis and hypertension. On the behavioral side, stress is associated with smoking and alcohol abuse, which favors the development of cardiovascular disease. According to these indicators, we can see that chronic stress can promote all other factors of atherogenesis (hypertension, lipid metabolism, smoking, obesity due to improper diet and inadequate physical activity). Finally, increased cardiac mortality has been associated with the stress from war, particular from post-traumatic stress disorder. Further studies and possibly clinical trials to intervene on persons with war stress are warranted to best identify those at highest risk where intervention may be helpful to reduce subsequent cardiovascular events. © 2012 Springer Science+Business Media, LLC. Source

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