ALBUQUERQUE, NM, United States
ALBUQUERQUE, NM, United States

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Palandro D.,ExxonMobil | Nedwed T.,ExxonMobil | Srnka L.,ExxonMobil | Thomann H.,ExxonMobil | Fukushima E.,Abqmr, Inc.
Proceedings of the 36th AMOP Technical Seminar on Environmental Contamination and Response | Year: 2013

As oil exploration moves into ice-prone regions, oil spill contingency planning will require a method to quickly and accurately detect oil under ice. Currently, the expected operational detection method is to deploy personnel on the ice with an ice auger to drill through the ice. There are several promising methods currently in the research phase. These technologies include ground-penetrating radar (GPR) and the use of autonomous underwater vehicles (AUVs) and remotely operated vehicles (ROVs). Another promising method to detect oil under/in ice is nuclear magnetic resonance (NMR). An initial evaluation by ExxonMobil has led to an agreement with ABQMR to design, build and test an NMR instrument to detect oil in the earth's magnetic field. Results to date have been promising. For tests at 0° C, NMR can differentiate Alaska North Slope (ANS) crude oil from seawater. Measurements in the earth's magnetic field have warranted the development of a flat transmitting/receiving antenna to match the flat geometry expected for oil under/in ice as well as rapidly responding NMR electronics that can detect short lived species such as crude oils. Recently, the flat coil prototype detected water in earth's magnetic field without prepolarization which validated the flat coil concept. In addition, ANS was detected in an independent earth's field experiment to demonstrate the rapid recovery time technology of the electronics. The final research hurdle to making NMR a viable tool to detect oil under/in ice is to minimize the seawater signal while enhancing the signal from the oil. This is currently under investigation with initial results expected in mid-2013.

Palandro D.,ExxonMobil | Nedwed T.,ExxonMobil | Demicco E.,ExxonMobil | Thomann H.,ExxonMobil | And 3 more authors.
Proceedings of the 38th AMOP Technical Seminar on Environmental Contamination and Response | Year: 2015

The application of existing remote sensing sensors and technologies for the detection of oil in and under ice is an ongoing and active research area. Currently, the suite of sensors that have and are being tested include acoustic, radar, optical and fluorosensors. Another technology being tested is Nuclear Magnetic Resonance (NMR) in the earth's magnetic field. NMR to detect oil in and under ice has undergone testing since 2006 and results to date have been promising. Field tests performed using a prototype 61 cm diameter flat transmitting/receiving antenna coil have differentiated seawater and Crisco®, a crude-oil surrogate. Current research has focused on scaling-up the prototype to increase the signal-to-noise ratio and allow the sensor to detect oil beneath ice that is up to 2 m thick. The coil currently being tested has a diameter of 6 m and uses aluminum wire in a modified figure-8 pattern. This coil is being tested at the Cold Regions Research and Engineering Laboratory in Hanover, New Hampshire, USA. The next phase of feasibility testing will use a full-scale prototype system flown under a helicopter over a specially designed ice basin.

Sanfratello L.,New Mexico Resonance | Sanfratello L.,University of New Mexico | Zhang J.,Duke University | Zhang J.,Indiana University - Purdue University Fort Wayne | And 3 more authors.
Granular Matter | Year: 2011

The distribution of the lengths of force chains in 2D granular assemblies of photoelastic disks was found to decay exponentially, with the decay length a quantitative measure of the way force is applied to the system. A plausibility argument is provided for why this statistic displays an exponential decay. © 2011 Springer-Verlag.

Kuethe D.O.,Abqmr, Inc. | Kuethe D.O.,Lovelace Respiratory Research Institute | Filipczak P.T.,Lovelace Respiratory Research Institute | Filipczak P.T.,Brigham And Womens Hospital | And 6 more authors.
American Journal of Physiology - Lung Cellular and Molecular Physiology | Year: 2016

Animal models play a critical role in the study of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). One limitation has been the lack of a suitable method for serial assessment of acute lung injury (ALI) in vivo. In this study, we demonstrate the sensitivity of magnetic resonance imaging (MRI) to assess ALI in real time in rat models of VILI. Sprague-Dawley rats were untreated or treated with intratracheal lipopolysaccharide or PBS. After 48 h, animals were mechanically ventilated for up to 15 h to induce VILI. Free induction decay (FID)-projection images were made hourly. Image data were collected continuously for 30 min and divided into 13 phases of the ventilatory cycle to make cinematic images. Interleaved measurements of respiratory mechanics were performed using a flexiVent ventilator. The degree of lung infiltration was quantified in serial images throughout the progression or resolution of VILI. MRI detected VILI significantly earlier (3.8 ± 1.6 h) than it was detected by altered lung mechanics (9.5 ± 3.9 h, P = 0.0156). Animals with VILI had a significant increase in the Index of Infiltration (P = 0.0027), and early regional lung infiltrates detected by MRI correlated with edema and inflammatory lung injury on histopathology. We were also able to visualize and quantify regression of VILI in real time upon institution of protective mechanical ventilation. Magnetic resonance lung imaging can be utilized to investigate mechanisms underlying the development and propagation of ALI, and to test the therapeutic effects of new treatments and ventilator strategies on the resolution of ALI. © 2016 the American Physiological Society.

Agency: Department of Health and Human Services | Branch: | Program: SBIR | Phase: Phase I | Award Amount: 317.29K | Year: 2011

DESCRIPTION (provided by applicant): Research using Xenopus (frog) embryos, a model system of major importance in many areas of biomedicine, is hampered in a fundamental way by their opacity. No device for non-destructively imaging the interiors of these specimens is generally available. The long-term goal at ABQMR, Inc. is to utilize unique capabilities in the field of miniaturized NMR and MRI instrumentation to develop new devices to overcome such problems in biomedical research and other fields. The objective for this application is a mature Ultra- Compact MRI (UC-MRI) prototype, ready for deployment in research labs, optimized in size, cost, and complexity to match the constraints of Xenopus embryology research. Preliminary experiments on phantoms, oocytes, and fixed embryos show that images at the necessary spatial and temporal resolutions are within reach of the current generation of miniaturized hardware. The central hypothesis driving this effort is that a fully miniaturized UC-MRI device can be constructed and operated in the biology research laboratory to produce images of live embryos of sufficient quality to answer important questions in Xenopus research. The rationale for this work is that the availability of a Xenopus-optimized UC-MRI device willdramatically increase the access to non-destructive MRI technology, improving data quality and enabling new types of research experiments utilizing Xenopus in a wide range of biomedical fields. The project has three staged specific aims. First, build a next generation UC-MRI prototype that meets the needs of Xenopus embryology research. Preliminary work indicates the required basic improvements: increased magnetic field gradient strength, lower temperature operation at 15: C and enhanced tissue contrast via selective fatty tissue excitation. Second, demonstrate that the UC-MRI can acquire research-quality Xenopus embryo images. Working in the RandD lab with slow growing late-stage embryos, the operating protocol of the Xenopus-optimized UC-MRI will be adjusted to provide images of sufficient quality to allow reproduction of published research analyses. Third, demonstrate the acquisition of research-quality images in a research setting. Images of fast growing early- stage embryos will be acquired by developmental biologists in their own lab. Given that existing prototypes are very small, rugged, and of modest cost, the accomplishment of these aims will show that this new, technically innovative miniaturization of MRI technology is fully capable of research-quality imaging in the hands of typical researchers. The ultimate product, a highly miniaturized UC-MRI device optimized in all respects for use in Developmental Biology, is significant because it establishes universal access to MRI instrumentation, instrumentation that overcomes the essential limitation imposed by opacity, yielding new and better data in Xenopus embryo research, and positively impacting many of the biomedical research areas funded by the NIH. PUBLIC HEALTH RELEVANCE: The proposed research is relevant to public health because it develops an important, currently missing tool for Xenopus embryology research, non-destructive imaging, which will further enhance the utility of this organism for addressing the fundamental biology of human disease. The project is relevant to the mission of the NCRR because it will establish a new resource for research, the Ultra-Compact MRI, which will allow scientists to advance their understanding of a wide range of diseases.

Abqmr, Inc. | Entity website

In the news. 69th New Mexico Regional NMR Meeting Saturday, September 17, 2016 Since 1982, the NMR community from around New Mexico has been meeting twice a year ...

Abqmr, Inc. | Entity website

SCIENTISTS Eiichi Fukushima Eiichi performed his first NMR experiment as a grad student at University of Washington in 1960. He worked at Los Alamos before coming to Lovelace Medical Foundation, Albuquerque, in 1985 to do flow NMR/MRI ...

Abqmr, Inc. | Entity website

As an outgrowth of our software development work for MRTechnology of Japan, we offer their Compact MRI system for sale in the US. The MRT system is a highly capable MRI console that has been optimized to work with permanent magnets ...

Abqmr, Inc. | Entity website

Please contact us if you have MRI or NMR applications that you would like us to consider. In many cases, it may be difficult to assess whether MRI or NMR might be valuable to your project ...

Abqmr, Inc. | Entity website

Last Updated March 26, 2016

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