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Perelman B.,Abie Biological Laboratories Phibro | Kin E.,Abie Biological Laboratories Phibro | Heifez S.,Abie Biological Laboratories Phibro | Benet-Noah C.,Abie Biological Laboratories Phibro | And 4 more authors.
Israel Journal of Veterinary Medicine | Year: 2012

During 2008 and as in previous years, severe outbreaks of turkey Meningoencephalitis (TME) occurred in many turkey farms in Israel. Many of the outbreaks occurred in turkey flocks in spite of vaccination, suggesting vaccination failure. Serological examination of vaccinated flocks revealed in many cases very low hemagglutination inhibition titers against the TME virus. To provide answers to the questions raised, a long term investigation study was carried out under laboratory and field conditions. In this report we describe the investigation of the problem of vaccination failure from the epidemiological aspects to the solution of the problem at field level. Based on the investigation and trial results, it was concluded that the vaccination failure of TME vaccines was probably related to technical problems and not to the vaccine itself. Some of the recommendations for vaccination included: The use of only high quality TME vaccines; pre-cool the diluent; use the vaccine within 60 minutes after dilution; vaccination is best carried out during the day; adapt the size of the needle to the size of the bird to be injected. Source

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