General Hospital Amalia Fleming

Athens, Greece

General Hospital Amalia Fleming

Athens, Greece
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Galani P.,General Hospital Amalia Fleming | Dimitrakopoulou G.,General Hospital Amalia Fleming
Folia Morphologica | Year: 2010

The inferior vena cava, also known as the posterior vena cava, is the large vein that carries de-oxygenated blood from the lower half of the body into the right atrium of the heart. Congenital anomalies of the inferior vena cava result from the persistence of the embryonic venous system. The majority of cases are clinically silent and are diagnosed in routine dissection studies, in retroperitoneal surgeries, or through imaging for other reasons. Although these anomalies are rare, they are of great importance during operations in the abdominal area or in the treatment of thromboembolic diseases. We report two cases of double vena cava and left vena cava, respectively, and a short review of the relevant literature. Copyright © 2010 Via Medica.


Grammatopoulou E.P.,Technological Educational Institute of Athens | Skordilis E.K.,National and Kapodistrian University of Athens | Georgoudis G.,Technological Educational Institute of Athens | Haniotou A.,General Hospital Amalia Fleming | And 4 more authors.
Journal of Asthma | Year: 2014

Introduction: The Nijmegen questionnaire (NQ) has previously been used for screening the hyperventilation syndrome (HVS) in asthmatics. However, no validity study has been reported so far. Objective: To examine the validity and reliability of the NQ in asthma patients and identify the prevalence of HVS. Methods: The NQ (n=162) was examined for translation, construct, cross-sectional and discriminant validity as well as for internal consistency and test-retest reliability. Results: Principal component analysis and exploratory factor analysis revealed a single factor solution with 11 items and 58.6% of explained variability. These 11 NQ items showed high internal consistency (Cronbach's alpha=0.92) and test-retest reliability (IR=0.98). Higher NQ scores were found in the following subgroups: women versus men (p<0.01); participants with moderate versus mild asthma (p<0.001) or uncontrolled versus controlled asthma (p<0.001), and participants with breath-hold time (BHT)<30 versus≥30s (p<0.01) or end-tidal CO2 (ETCO2) ≤35 versus >35mmHg (p<0.001). A cut-off score of >17 discriminated the participants with regard to the presence of HVS. The NQ showed 92.73% sensitivity and 91.59% specificity. The total NQ score was found significantly correlated with ETCO2 (r=-0.68), RR (r=0.66) and BHT (r=-0.65). The prevalence of HVS was found 34%. Conclusion: The NQ is a valid and reliable questionnaire for screening HVS in patients with stable mild-to-moderate asthma. © 2014 Informa Healthcare USA, Inc.


Grammatopoulou E.,National and Kapodistrian University of Athens | Haniotou A.,General Hospital Amalia Fleming | Douka A.,National and Kapodistrian University of Athens | Koutsouki D.,National and Kapodistrian University of Athens
Journal of Asthma | Year: 2010

Background. The association between asthma and obesity remains controversial and limited to a few studies. Objective. The present study was designed to examine the association between body mass index (BMI) and clinical measures of asthma morbidity in Greek asthma patients. Study Design. A cross-sectional study in 100 outpatients at the asthma department of the 'Amalia Fleming' General Hospital in Athens, Greece, was conducted. Asthma diagnosis was confirmed by a specialist, according to Global Initiative for Asthma (GINA) guidelines. Participants were classified, with respect to BMI (kg/m 2), in three groups: normal: <25.0, overweight: 25.0-29.9.0 and obese: ≥30.0. Data were modeled through multiple logistic regression analysis for the association of overweight/obesity with the study variables: demographics, asthma severity, smoking, pulmonary function (forced expiratory volume in one second; FEV1), asthma control (Asthma Control Test; ACT), disability associated with dyspnea (Medical Research Council MRC breathlessness scale), and physical activity in leisure time. Results. Overweight/obesity was detected in 56 participants (56%). Multivariate regression analysis resulted in an excess risk of overweight/obesity for older participants (odds ratio OR: 1.71, 95% confidence interval CI: 1.10-2.64 for a 10-year increase in age). Conclusion. Age seems to be highly associated with overweight/obesity in Greek adults with asthma who tend to maintain a similar body weight compared to the general population. Copyright © 2010 Informa Healthcare USA, Inc.


Kapetanakis S.,General Hospital Amalia Fleming | Vasileiadis I.,General Hospital Amalia Fleming | Papanas N.,University Hospital of Alexandroupolis | Goulimari R.,General Hospital Amalia Fleming | Maltezos E.,University Hospital of Alexandroupolis
Wiener Klinische Wochenschrift | Year: 2011

Cervical spondylosis is a common disorder mainly affecting elderly people. It frequently presents with excessive bone formation (osteophytes). These may lead to pain and neurological deficits due to root compression. Dysphagia and airway obstruction due to a giant anterior osteophyte of the cervical spine are extremely rare. We present the case of an 81-year-old patient suffering from dysphagia and slight dyspnoea due to a giant cervical osteophyte. Osteophyte resection was performed and the patient was relieved from symptoms. This case highlights that a large cervical osteophyte may, albeit rarely, be the cause of simultaneously presenting dysphagia and dyspnoea, and should, therefore, be included in the diagnostic workup in such cases. © 2011 Springer-Verlag.


Zaga T.,University of Thessaly | Makris D.,University of Thessaly | Tsilioni I.,University of Thessaly | Kiropoulos T.,University of Thessaly | And 3 more authors.
Monaldi Archives for Chest Disease - Pulmonary Series | Year: 2011

Background and Aim. Hyaluronic acid (HA) is a component of extracellular matrix and may play a role in the pleural inflammation which is implicated in parapneumonic effusions.The aim of the current study was to investigate HA levels in serum and pleura in patients with parapneumonic effusions. Methods. We prospectively studied pleural and serum levels of HA in 58 patients with pleural effusions due to infection (complicated and uncomplicated parapneumonic effusions), malignant effusions and transudative effusions due to congestive heart failure. In addition to HA, TNF-α and IL-1β levels were determined in pleural fluid and serum by ELISA. Results. The median±SD HA levels (pg/ml) in pleural fluid of patients with complicated effusions (39.058±11.208) were significantly increased (p<0.005), compared to those with uncomplicated parapneumonic effusions (11.230±1.969), malignant effusions (10.837±4.803) or congestive heart failure (5.392±3.133). There was no correlation between pleural fluid and serum HA values. Pleural fluid TNF-α levels (146±127 pg/mL) and IL-1β levels (133.4±156 pg/mL) were significantly higher in patients with complicated parapneumonic effusions compared to patients with other types of effusion (p<0.05). No significant association between HA and TNF-α or IL-1β was found. Conclusions. HA may play a significant role in the inflammatory process which characterises exudative infectious pleuritis. Further investigation might reveal whether HA is a useful marker in the management of parapneumonic effusions.


PubMed | General Hospital Amalia Fleming
Type: Comparative Study | Journal: Folia medica | Year: 2010

Hemiarthroplasty is the treatment of choice in the management of displaced intracapsular fractures of the proximal femur in old patients with low functional demands.To assess the effectiveness of cementless Austin-Moore and the cemented Thompson prostheses used in the treatment of displaced intracapsular fractures of the proximal femur.We studied retrospectively 376 patients with fresh, displaced, nonpathological femur neck fractures. They were treated with either a cementless Austin-Moore prosthesis or a cemented Thompson prosthesis. Criteria for the choice of the prosthesis were the fracture site on the neck of the femur and the bone quality. The follow-up period was 3 to 8 years and the number of reviewed patients was 122.The Thompson prosthesis group showed slightly better results. Acetabular erosion rate was significantly lower in the uncemented group while loosening rate here was significantly higher.Advantages and disadvantages were identified in both groups although we believe that none of the approaches proved definitively superior to the other.


PubMed | General Hospital Amalia Fleming
Type: | Journal: The open orthopaedics journal | Year: 2011

The aim of this study was to evaluate the changes in quality of life of patients after total knee arthroplasty and to assess the changes in physical activity by using a self-reported questionnaire and by counting the number of steps 3-6 months after post-operatively.Included were fifty two elderly women (age 72.665.9 years, meanSD) with knee osteoarthritis undergoing primary knee arthroplasty. Health-related quality of life, physical activity, pain and function and the number of steps were assessed before, 3 and 6 months post-operatively. We used the Medical Outcomes Study Short Form (SF-36), the Physical Activity Scale for the Elderly (PASE) and the pedometer SW200 Digiwalker of Yamax.Patients showed a significant improvement (p< 0.01, 2 =0.22) in health-related quality of life, particularly in physical function, (p<0 .001) body pain (p< 0.001) and vitality scale (p< 0.001) of SF-36 at 3 and 6 months after the procedure. Physical activity (PASE score) increased at 3 and 6 months after arthroplasty (p< 0.001, 2 =0.74), and the number of steps increased 6 months after, compared to the assessment that took place 3 months after operation (p< 0.001).Our results suggest that total knee arthroplasty leads to a gradual improvement in quality of life of elderly patients over the first 6 post-operative months.

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