Jayasree K.V.,NGM College |
Neelakanndeswari K.,Sri Ramakrishna Engineering College Vattamalaipalayam |
Elayarajah B.,A Biosolution Company |
Rajesh R.,A Biosolution Company
International Journal of Applied Engineering Research | Year: 2015
Synthesizing and characterizing the Copper oxide nanoparticles (CuO-NPs) were selected as the preliminary objective in the present study. Coating the nanoparticles onto the implant surface for preventing bacterial contamination was selected as the secondary objective. Nanoparticles were prepared by adopting aqueous precipitation method using copper sulphate pentahydrate as a precursor and glucose as reducing agent. Characterization of the particles was analyzed for studying its structure and composition using XRD, DLS, UV absorption photoluminescence, SEM and EDX. The synthesized nanoparticles were coated on dental implant surface for the prevention of bacterial colonization. XRD results showed 20.3848nm as the average size of CuO-NPs. DLS analysis demonstrated that 95% of the particles are in the colloidal form. The presence of CuO in the synthesized nanoparticles was revealed based on the peak values obtained from UV-absorption photoluminescence studies. Aggregation of nanoparticles was analyzed from the SEM images magnified under 20,000X. No peaks representing the impurities in synthesized nanoparticles were observed during EDX analysis. Antibacterial activity obtained for the CuO-NPs coated implants showed significant inhibition on dental pathogens, Staphylococcus sp and Escherichia coli. Thus the results obtained in the present research revealed that aqueous precipitation method is a reliable and cheap method for the development of CuO-NPs. The synthesized NPs were also proved to be effective in preventing the dental-implant associated infections. © Research India Publications.