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Az Zāwīyah, Libya

Sharma D.N.,7th of April University | Hanesh M.,Zawia Teaching Hospital | Mohamed M.,7th of April University | Yahya A.A.M.,University of Medical Sciences and Technology
Jamahiriya Medical Journal | Year: 2010

Aim: To assess the response in pain control after the use of two drugs, diclofenac versus ketoprofen, in the process of phonophoresis. Methodology: One hundred and fifty Libyan patients with soft tissue injuries of knee joint were randomly assigned to receive phonophoresis with diclofenac (group A) or ketoprofen (group B). Both groups received ultrasound therapy three times per week for two weeks. The patients indicated their pain level by marking on a visual analog pain scale (VAS) at the start of treatment, and at the end of the second week. ANOVA for repeated measures was used to analyse the data. Results: At the end of two weeks of treatment, both groups showed a significant decrease in pain level, but for group B pain level decreased more significantly than group A. Conclusion: We conclude that process of therapeutic phonophoresis with ketoprofen gel is significantly more effective than diclofenac gel in reducing the pain of soft tissue injuries of the knee joint. Source

Marinkovic A.D.,University of Belgrade | Jovanovic B.Z.,University of Belgrade | Assaleh F.H.,7th of April University | Vajs V.V.,University of Belgrade | Juranic M.I.,University of Belgrade
Journal of Molecular Structure | Year: 2012

Linear free energy relationships (LFER) were applied to the kinetic data and 13C NMR chemical shifts in 4-[[(substituted phenyl)imino]methyl] benzoic acids. The correlation analysis for the kinetic data and substituent-induced chemical shifts (SCS) with σ using single substituent parameter (SSP), as well as inductive (σ I) and various resonance (σ R) parameters using dual-substituent parameter (DSP), were carried out. The presented calculations account satisfactorily for the polar and resonance substituent effects having similar contributions at all carbons studied. Negative ρ values were found for several correlations (reverse substituent effect). Exceptionally good Hammett correlation of 13C NMR chemical shifts of azomethine carbon with electrophilic substituent constants σ + indicates a significant resonance interaction in the aniline part of molecules. The conformations of investigated compounds have been studied by the use of DFT method, and together with 13C NMR chemical shifts and kinetic data, give a better insight into the influence of such a structure on the transmission of electronic substituent effects. New σ constants for substituted phenyliminomethyl group have been calculated. © 2010 Elsevier B.V. All rights reserved. Source

Kumar R.S.,Tamil University | Kumar K.A.,7th of April University | Murthy N.V.,JKK Nataraja Dental College and Hospital
Natural Product Research | Year: 2012

The aim of this study is to investigate the antitumour and antioxidant activities of the ethanol extract of Scutia myrtina (EESM) against Ehrlich's ascites carcinoma (EAC) in mice. Twenty-four hours after tumour inoculation, EESM was administered at doses 100, 200 and 300mgkg1 bodyweight/mice/day for 21 days. EESM caused a significant (p<0.01) decrease in ascites volume, packed cell volume and viable cell count, and also prolonged the life span of EAC tumour-bearing mice. Haematological profiles reverted to near-normal levels in extract-treated mice (p<0.01). EESM also produced protective effects by significantly decreasing the activity of serum enzymes and bilirubin and increasing the protein and uric acid levels (p<0.05). EESM significantly (p<0.05) decreased the levels of lipid peroxidation, while it significantly (p<0.05) increased the levels of enzymatic and non-enzymatic antioxidants. The results indicate that EESM exhibited significant antitumour and antioxidant activities in EAC-bearing mice. © 2012 Taylor & Francis. Source

Srivastava U.C.,Allahabad University | Sakal I.D.,7th of April University | Maurya R.C.,Allahabad University
Proceedings of the National Academy of Sciences India Section B - Biological Sciences | Year: 2012

The present study, based on neurohistological techniques (Golgi impregnation), focuses on the morphological and numerical changes in the dendritic spines of neuronal classes of the cerebral cortex in Calotes versicolor. The cerebral cortex in reptiles occupies the roof of the cerebral hemisphere and is divided into four regions viz. medial, dorsomedial, dorsal and lateral cortex. Using different characteristics such as criteria of location, dendritic tree pattern, dendritic spine covering and soma shape different neuronal types have been distinguished in the cell layer-II of medial, dorsomedial, dorsal and lateral cortex. The dendritic diameter, spine length and diameter of spine head show almost uniform pattern in all cortical regions except being slightly higher in case of the neurons of dorsomedial cortex. The multipolar and pyramidal neurons show higher dendritic diameter, spine length, spine head diameter and dendritic spine density in comparison to other neurons. The density of these neurons acts as the indicator of high or low activity of a particular region. © The National Academy of Sciences, India 2012. Source

Zayed A.S.,7th of April University | Elfandi M.,University of Tripoli | Twiel M.,Higher Institute of Medical Profession
Proceedings of the IASTED International Conference on Modelling, Identification and Control | Year: 2010

This article presents a new non-linear PID adaptive controller algorithm incorporating a radial bases function (RBF) neural network based generalised learning model (GLM). The GLM assumes that the unknown non-linear plant is represented by an equivalent model consisting of a linear time-varying sub-model plus a non-linear RBF neural networks sub-model. The parameters of the linear sub-model are identified by a recursive least squares algorithm with a directional forgetting factor, whereas the unknown non-linear sub-model is modelled using the RBF neural network resulting a new non-linear controller with a generalised minimum variance performance index. In addition, the proposed controller has a PID structure and overcomes the shortcomings of other linear designs and provides an adaptive mechanism which ensures that both the closed-loop poles and zeros are positioned at their pre-specified places. It can track set-point changes with the desired speed of response, penalises excessive control action, and can be applied to non-minimum phase systems and unstable systems. Example simulation results using a non-linear plant model demonstrate the effectiveness of the proposed controller. Source

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