Korigaoka Yukeikai Hosp.

Japan

Korigaoka Yukeikai Hosp.

Japan

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Fujita Y.,Osaka Kaisei Hospital | Tada R.,Tada Ophthalmol. Clin. | Katsumura C.,Keiseikai Hosp. | Okuno T.,Korigaoka Yukeikai Hosp. | Ikeda T.,Osaka Kaisei Hospital
Japanese Journal of Clinical Ophthalmology | Year: 2011

Purpose: To report a case of tuberculous uveitis followed by thrombocytopenia. Case: A 29-year-old female presented with floaters in the right eye since one week before. Findings: Corrected visual acuity was 0.6 right and 1.0 left. The right eye showed signs of iritis, vitreous opacity and retinal periphlebitis. Tuberculin test was strongly positive. Platelet count was 136 × 103/μl. It decreased to 12 × 10 3/μl 5 weeks later associated with generalized purpura. Bone biopsy showed bone marrow hypoplasia. Massive dosis of immunoglobulin was followed by normal level of platelets. Mediastinal biopsy showed cheese necrosis of lymphnoids. Culture was negative for tuberculosis. The findings were suggestive of allergic reaction to tuberculous bacilli. Systemic antituberculous therapy with prednisolone was followed by improved fundus findings one week later. She was declared as cured 6 months later. Conclusion: This case illustrates that acute thrombocytopenia may follow tuberculous uveitis or retinal periphlebitis.

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