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Chengdu, China

Ye Y.,452nd Hospital of PLA
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi | Year: 2013

To determine the multidetector computed tomography (MDCT) features as well as the anatomic-pathological basis in thyroid diseases involving the upper mediastinum, we performed a retrospective analysis of 49 patients who had thyroid diseases involving the upper mediastinum. In the study, 22 cases were nodular goiter, 13 cases were thyroid adenoma, and 14 cases were thyroid cancer. The relevance between MDCT appearances and their diffusing route of common thyroid diseases as well as the anatomic-pathological features in this region were evaluated. It was found that the lesions located in the upper anterior mediastinum, the upper posterior mediastinum, and both sides were 67.3% (33/49), 14.3% (7/49), 18.4% (9/49), respectively. Different diseases had their distinct MDCT features nodular goiter mainly showed localized and multiple nodules or tumor bulk (77.3%), thyroid adenoma mainly showed solitary tumor bulk (92.3%), and thyroid cancer mainly demonstrated solitary tumor bulk (57.1%), respectively. Among the 49 cases, 9 cases had cervical and/or mediastinal metastases in lymph nodes. The thyroid diseases involving the upper mediastinum most commonly occurred in the upper anterior mediastinum. The MDCT features and distribution of diffusing thyroid lesions in cervico-thoracic junctional region closely correlated with the anatomic-pathological characteristics in this region. Source


Zhang Q.-Q.,University of Sichuan | Zhang X.-J.,University of Sichuan | Chang B.-B.,General Hospital of Chengdu Military Region | Qiu B.-Y.,University of Sichuan | And 3 more authors.
Journal of Sichuan University (Medical Science Edition) | Year: 2011

Objective: To investigate the relationship between blood pressure variability (BPV) and targetorgan damage in elderly patients with hypertension. Methods A total of 197 elderly patients were included in the study. The participants were divided into two groups, those with hypertension (n= 146) and those without hypertension (Control, n = 51). The 24 h systolic and diastolic blood pressure variability (24 h SBPV/DBPV),24 h average systolic and diastolic blood pressure (24 h SBP/DBP), day time systolic and diastolic blood pressure variability (d SBPV/DBPV) ,and night time systolic and diastolic blood pressure variability (n SBPV/DBPV) were measured. The hypertensive group was further divided into low and high variability groups according to the 50th percentile of 24 h SBPV. The carotid artery intima-media thickness (IMT), left ventricular mass index (LVMI) ,24 h microalbuminuria (MA) and basic clinical and laboratory parameters were compared among the groups. The correlations between blood pressure variability and IMT, LVMI, and MA were analyzed with multivariable regression analyses. Results The patients with essential hypertension had significantly higher 24 h SBPV (P< 0. 001) and d SBPV (P<0. 05) than those without hypertension. The patients with higher blood pressure variability had greater incidence of plaque and cardiovascular disorder,as well as IMT,LVMI and MA (P<0. 001). The prevalence of diabetes mellitus (DM) differed significantly among the three groups of participants (P<0. 05). The multivariable regression analysis showed that 24 h SBPV was independently correlated with IMT, LVMI and MA. Conclusion Elderly patients with hypertension have high BPV, which is an important independent predictor of target-organ damage. Source


Zhou L.,Chengdu Military General Hospital.No.270 Rongdu Avenue | Zhou L.,University of Electronic Science and Technology of China | Sun Y.,452nd Hospital of PLA | Hua S.,University of Electronic Science and Technology of China | And 4 more authors.
2015 IEEE 12th International Conference on Electronic Measurement and Instruments, ICEMI 2015 | Year: 2016

A bowel sound signal is very significant to clinical diagnosis of diseases, but it is a weak, non-stable and aperiodic signal generated under a strong noisy background. How to filter out the background noise effectively and provide real and clear signal for clinical diagnosis? This is one of the concerns in medical engineering field. This study proposes a detection method which is based on dynamic weighing threshold. With this method, the spectral entropy of every noise frame to be determined and the spectral entropy of noise in silent period are weighted to obtain new spectral entropy of noise which is used as the updated threshold. The spectral subtraction is used in the determination to increase signal-to-noise ratio for further decrease in noise interference. The simulation experiment results indicate that, compared to traditional method for spectral entropy endpoint detection, this method is more accurate in detecting the endpoint of bowel sounds in low signal-to-noise ratio condition. © 2015 IEEE. Source


Ye Y.,452nd Hospital of PLA
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi | Year: 2012

To determine the relevance between MDCT features and anatomic-pathological basis of lymphoid neoplasm in cervico-thoracic junctional region, we performed a retrospective analysis of 69 patients with lymphoid neoplasm (lymphoma: 41 patients; metastatic tumor: 28 patients) involving the cervico-thoracic junctional region for MDCT features and distribution of lesions. The relevance between MDCT features and the anatomic-pathological basis in this region were evaluated. Among all the 41 patients with lymphoma, 29 with NHL (70.7%), 12 with HD (29.3%). The lymphomatous lymphadenopathy mainly located in superficial lateral cervix (51.2%, 21/41) ,deep jugular chain (65.9%, 27/41), supraclavicular fossa (75.6%, 31/41), paratrachea space in anterior mediastinum (46.3%, 19/41), around aortic arch (56.1%, 23/41), aortopulmonary window (53.7%, 22/41), upper anterior mediastinum (41.5%, 17/41), subcarinal space (26.8%, 11/41) and paraesophageal space (17.1%, 7/41). 28 patients had metastatic lymphoid tumor. The primary tumor were nasopharynx tumor (5 patients), thyroid cancer (7 patients), lung cancer (10 patients), and esophageal cancer (6 patients). Most metastasis took stage by stage in the way of lymphatic return, but a minority of cases migrated jumpily. The main metastatic sites were: beside jugular chain (82.1%), supraclavicular fossa (75%), paratracheal in anterior mediastinum (60.7%), upper anterior mediastinum (64.3%), beside aortic arch (35.7%), aortopulmonary window (39.2%), and paraesophageal space (28.6%). So lymphoid neoplasms in cervico-thoracic junctional region were involving both lower cervix and upper thorax simultaneously. The MDCT features and main distribution of lesions correlated with the anatomic-pathological characteristics in this region. Source


Wang Y.,Xihua University | Wang H.,Xihua University | Liu L.,Xihua University | Qiao J.,452nd Hospital of PLA
Proceedings - International Conference on Electrical and Control Engineering, ICECE 2010 | Year: 2010

To compensate for the deficiencies of traditional wavelet threshold shrinkage denoising algorithm and obtain the heart sounds with high SNR, an improved wavelet threshold shrinkage algorithm is proposed in this paper. The algorithm uses a new subband adaptive threshold and a new threshold function to quantify the detail coefficients of wavelet decomposition of noisy heart sounds, and its denoising effect is assessed with signal to noise ratio (SNR) and the root mean square error (RMSE). First, the proposed subband adaptive threshold and the several traditional thresholds are applied to the noise reduction of soft threshold function respectively to verify the superiority of the proposed subband adaptive threshold by the comparison of the denoising effects of 22cases of standard heart sounds in 3M database. Second, the new subband adaptive threshold is applied to the noise reduction of the new threshold function based on genetic algorithm optimization and traditional soft and hard threshold functions respectively to validate the denoising performance of the proposed threshold function. Finally, the improved threshold shrinkage denoising algorithm is used to do noise reduction for 20 cases of the clinical heart sounds. The results indicate that the improved wavelet threshold shrinkage denoising algorithm can eliminate noise more effectively, and has strong clinical value. © 2010 IEEE. Source

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