Beijing 401 Hospital of China Nuclear Industry

Beijing, China

Beijing 401 Hospital of China Nuclear Industry

Beijing, China
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Zhang C.,Beijing 401 Hospital of China Nuclear Industry | Chen N.,Capital Medical University | Li K.-C.,Capital Medical University
Chinese Journal of Medical Imaging Technology | Year: 2012

Anterior cingulate cortex is an important part of the limbic system, and has been found to be strongly associated with emotions, cognition and executive function, playing an important role in both occurrence and development of several psychiatric diseases. The anatomical structure, functional subdivisions and progress of correlative diseases were reviewed in this article.


Zhang C.,Beijing 401 Hospital of China Nuclear Industry | Chen N.,Capital Medical University | Wang X.,Capital Medical University | Zhuo Y.,CAS Institute of Biophysics | And 2 more authors.
Chinese Journal of Medical Imaging Technology | Year: 2012

Objective: To assess the correlations of cingulate gyrus volume with corrected factor, in order to provide standard volumetric method for cingulate gyrus. Methods: Totally 627 Chinese healthy volunteers (aged from 18 to 60) underwent brain three-dimensional MR scan. Cingulate gyrus volumes were manually measured with ROI using 3D volume analysis software, and were corrected by total intracranial volume (TIV) and whole brain volume (WBV), respectively. Correlation of uncorrected and corrected cingulate gyrusvolumes with TIV and WBV were analyzed, respectively. Results: Uncorrected and corrected cingulate gyrus volume by TIV and WBV was (21.01±2.31)ml, (21.11±2.57)ml, (21.06±2.34)ml respectively for male, (19.72±2.31)ml, (19.79±2.28)ml, (19.74±2.04)ml respectively for female, (9.71±1.54)ml, (9.77±1.61)ml, (9.75±1.54)ml respectively for left side, (10.64±1.58)ml, (10.69±1.53)ml, (10.67±1.45)ml respectively for right side. Uncorrected cingulate gyrus volumes had lower correlation with TIV (male, female: r=0.225, 0.385; left, right: r=0.229, 0.366; all P<0.05), and higher correlation with WBV (male, female: r=0.329, 0.473; left, right: r=0.381, 0.419; all P<0.05). Corrected cingulate gyrus volumes were correlated with TIV (male, female: r=-0.378, -0.379; left, right: r=-0.368, -0.300; all P<0.05), and had lower correlation with WBV (male, female: r=-0.297, -0.156; left, right: r=-0.285, -0.197; all P<0.05). Conclusion: There is correlation between cingulate gyrus volume and TIV or WBV. Cingulate gyrus volume corrected with WBV is better.


Zhang C.,Capital Medical University | Zhang C.,Beijing 401 Hospital of China Nuclear Industry | Chen N.,Capital Medical University | Wang X.,Capital Medical University | Li K.-C.,Capital Medical University
Chinese Journal of Radiology | Year: 2010

Objective: To explore the normal range of cingulate cortex volumes of Chinese adults of the Han nationality and its relationship with age, which provide morphological data for the construction of database for Chinese Standard Brain. Methods: This is a clinical multi-center study. One thousand Chinese healthy volunteers (age range = 18 to 70) recruited from 15 hospitals were divided into 5 groups, i. e., Gr oup A (age range = 18 to 30), B (age range = 31 to 40), C (age range = 41 to 50), D (age range = 51 to 60), and E (age range = 61 to 70). Each group contained 100 males and 100 females. All of the volunteers were scanned by MR using T 1 weighted three-dimensional magnetization prepared rapid acquisition gradient echo sequence. Cingulate cortex volume (including bulk volume and the left/right volume) was measured semi-manually using 3D volume analysis software. Cingulate cortex volumes among age groups were compared by one-way ANOVA. Right and left cingulate cortex volumes between sexualities were analyzed by paired samples t test. The relationship between cingulate cortex volume and age was analyzed by Pearson correlations and regression analysis. Results: Cingulate cortex volumes of male and female were (20 347±2504) and (19 432±2184) mm 3 respectively, and the male's was significantly larger than that of female's (two sample t′-test for independent samples, t′ -6.156, P<0.05). Right and left cingulate cortex volumes of male were (10717±1629) and (9630±1498) mm 3 respectively, and those of female's were (10 064±1407) and (9368±1441) mm 3 respectively. The volumes of cingulate cortex were significantly different between right and left in male or female (t = -12.960, -8.511, P<0.05), and right was larger than left. Bilateral cingulate cortex volume in male among group A, B, C, D and E[left: (10 132±1291), (10 113±1638), (9599±1576), (9594±1288), (8710±1212) mm 3; right: (11 212±1442), (11096±1602), (11 040±1403), (10 633±1638), (9604±1522) mm 3] had statistical differences (F = 16.738, 18.707, P<0.01); and those in female among five age groups [left: (9689±1426), (9652±1676), (9347±1500), (9098±1225), (9053±1233) mm 3; right; (10558±1325), (10 266±1463), (10 100±1497), (9779±1304), (9617±1254) mm 3] also had significant differences (F = 16.859, 7.528, P<0.01). Bilateral cingulate cortex volume in both male and female were negatively correlated with age (r = -0.330, -0.324, -0.169, -0.243, P<0.05), though the correlation coefficient is not high. Conclusions: Cingulate cortex volume could be accurately measured on the high-resolution MRI with 3D volume analysis software, which can provide morphological data for the construction of database for Chinese Standard Brain. The Results: may provide normal range for the diagnosis of the volumetric deficits of cingulate cortex. © 2010 by the Chinese Medical Association.

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