Risko P.,II. interni klinika FNKV |
Kraml P.,II. interni klinika FNKV |
Potockova J.,II. interni klinika FNKV |
Strizova J.,II. interni klinika FNKV
Interni Medicina pro Praxi | Year: 2012
Statins have been extensively prescribed for its ability to reduce blood cholesterol level and positive impact on cardiovascular diseases. In recent years, increased evidence of its pleiotropic effects-antioxidant, antithrombotic, anti-inflammatory, immunomodulatory effect, possible anti-foam cell effect and improving of endothelial dysfunction. In this review, is outlined possible mechanism of antiinflammatory and immunomodulatory effect of statins.