Weaver K.N.,160 W. Ogden Ave |
Jones R.C.,160 W. Ogden Ave |
Albright R.,Advocate Hospitals |
Thomas Y.,Advocate Hospitals |
And 5 more authors.
Infection Control and Hospital Epidemiology | Year: 2010
objective. To describe an outbreak of infection associated with an infrequently implicated pathogen, Elizabethkingia meningoseptica, in an increasingly prominent setting for health care of severely ill patients, the long-term acute care hospital. design. Outbreak investigation. setting. Long-term acute care hospital with 55 patients, most of whom were mechanically ventilated. methods. We defined a case as E. meningoseptica isolated from any patient specimen source from December 2007 through April 2008, conducted an investigation of case patients, obtained environmental specimens, and performed microbiologic testing. results. Nineteen patients had E. meningoseptica infection, and 8 died. All case patients had been admitted with respiratory failure that required mechanical ventilation. Among the 8 individuals who died, the time from collection of the first specimen positive for E. meningoseptica to death ranged from 6 to 43 days (median, 16 days). Environmental sampling was performed on 106 surfaces; E. meningoseptica was isolated from only one swab. Three related pulsed-field gel electrophoresis patterns were identified in patient isolates; the environmental isolate yielded a fourth, unrelated pattern. conclusion. Long-term acute care hospitals with mechanically ventilated patients could serve as an important transmission setting for E. meningoseptica. This multidrug-resistant bacterium could pose additional risk when patients are transferred between long-term acute care hospitals and acute care hospitals. © 2009 by The Society for Healthcare Epidemiology of America. Source
Pacilli M.,160 W. Ogden Ave |
Cortese M.M.,Centers for Disease Control and Prevention |
Smith S.,160 W. Ogden Ave |
Siston A.,160 W. Ogden Ave |
And 8 more authors.
Clinical Infectious Diseases | Year: 2015
Background. Rotavirus infection in adults is poorly understood and few rotavirus outbreaks among US adults have been reported in the literature. We describe an outbreak due to genotype G12P rotavirus among medical students, faculty, and guests who attended a formal dinner event in April 2013. Methods. A web-based questionnaire was distributed to event attendees to collect symptom and exposure data. A clinical case was defined as a person who developed diarrhea after attending the formal event. A laboratory-confirmed case was defined as a clinical case who attended the formal event, with rotavirus detected in stool by enzyme immunoassay or reverse transcription-polymerase chain reaction (RT-PCR) assay. Results. Among 334 dinner attendees, 136 (41%) completed the web-based questionnaire; 58 (43%) respondents reported illness. Symptom onset ranged from 1 to 8 days, with peak onset 3 days after the event. In addition to diarrhea, predominant symptoms included fever (91%), abdominal pain (84%), and vomiting (49%). The median duration of illness was 2.5 days. Thirteen (22%) of 58 cases sought medical attention; none were hospitalized. Analysis of food exposures among questionnaire respondents did not identify significant associations between any specific food or drink item and illness. Stool specimens were negative for bacterial pathogens by culture and negative for norovirus by RT-PCR assay; 4 specimens were positive for rotavirus by enzyme immunoassay or PCR. G12P-R1-C1-M1-A1-N1-T1-E1-H1 was identified as the causative full-genome genotype. Conclusions. Rotavirus outbreaks can occur among adults, including young adults. Health professionals should consider rotavirus as a cause of acute gastroenteritis in adults. © 2015 The Author 2015. Source