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Liu X.Z.,Hangzhou Sanatorium of Nanjing Military Command Region | Liu X.Z.,Shanghai University | Yin K.,Shanghai University | Fan J.,Hangzhou Sanatorium of Nanjing Military Command Region | And 6 more authors.
Surgery for Obesity and Related Diseases | Year: 2015

Background Laparoscopic adjustable gastric banding (LAGB), as one major bariatric surgery for treatment of obesity, results in ineffective long-term weight loss and a high reoperation rate. The objective of this study was to evaluate the long-term effects of LAGB on the weight loss outcomes and reoperation rates of obese patients with different body mass index (BMI) levels in China. Methods A retrospective study was performed to review the follow-up data of obese patients who underwent LAGB at Shanghai Changhai Hospital between November 2003 and May 2013. The main outcomes included weight loss, percentage excess weight loss (%EWL), reoperation rate, and reasons for reoperation. Results A total of 254 LAGB procedures were performed in our hospital. By the end of May 2013, 145 Chinese patients (57.8%) were followed up, 99 patients with BMI≥35 kg/m2 (high BMI group) and 46 patients with BMI<35 kg/m2 (low BMI group). In the high BMI group, the mean %EWL was>25% within 5 years postoperatively, but it decreased to less than 25% after 5 years. However, in the low BMI group, the mean %EWL at each time point was over 50%. The reoperation rate was 33.1%; it was 17.4% in the low BMI group and 34.3% in the high BMI group. Conclusion LAGB is more effective with a lower reoperation rate for obese patients with a BMI<35 kg/m2 compared to BMI≥35 kg/m2 in our population. © 2015 American Society for Bariatric Surgery. All rights reserved.


Yu X.,Navy General Hospital | Huang R.,117 Hospital of PLA | Qian W.,117 Hospital of PLA | Fang J.,117 Hospital of PLA | And 3 more authors.
British Journal of Neurosurgery | Year: 2012

Objective. Stereotactic radiosurgery (SRS) has been developed as a clinical treatment method for certain brain tumours that does not need craniotomy. As a more accurate radiation technique, SRS can deliver a relatively large dose of stereotactic radiation to a conformal target with less normal brain tissue irradiated in a single treatment. The aim of this study is to evaluate the therapeutic effects of SRS for Rathke's cleft cysts (RCCs). Methods. SRS was performed using a rotating gamma ray unit in seven selected patients with symptomatic RCCs diagnosed upon typical MR imaging combined with clinical manifestation. The patients included one male and six females with an age range from 25 to 63 years (mean 43.4 years). Five patients presented with headache, three with menstrual disorder or infertility and one with vision impairment. No other endocrine dysfunction was observed. SRS was performed in the patients with a central dose varied from 22.6 to 40 Gy (mean 32.5 Gy) and a peripheral dose from 9 to 20 Gy (mean 13.4 Gy). Results. The patients were followed up for 11105 months (mean 38.6 months) after SRS. All symptoms that presented before treatment were relieved within 36 months post-SRS and no endocrine dysfunction was developed during the follow-up period. MR imaging demonstrated that the RCCs were completely disappeared in five cases and significantly shrunken in the other two cases. No recurrence was observed in any cases during the follow-up. Conclusion. This study demonstrates that SRS can treat RCCs effectively without evident side effects. © 2012 The Neurosurgical Foundation.


Bing S.,PLA Fourth Military Medical University | Zhang C.,PLA Fourth Military Medical University | Zhang C.,117 Hospital of PLA | Wang L.,PLA Fourth Military Medical University | And 2 more authors.
Blood Pressure Monitoring | Year: 2015

Objective: The study aimed to determine the accuracy of the fully automated oscillometric upper-arm blood pressure (BP) monitor Pangao PG-800B11 according to the European Society of Hypertension-International Protocol (ESH-IP) revision 2010 and the British Hypertension Society (BHS) protocol 1993. Materials and methods: Data from 33 participants were initially examined according to the ESH-IP revision 2010. Furthermore, 52 participants were then enrolled to fulfill the BHS protocol requirements. In all participants, sequential left arm measurements were performed by two trained observers using a mercury sphygmomanometer and one supervisor using the device. The protocols' requirements were followed precisely. Results: The device passed all parts of the ESH protocol for systolic blood pressure (SBP) and diastolic blood pressure (DBP) and was graded A according to the criteria of the BHS protocol for both SBP and DBP. The A/A grade was achieved in low (<130/80mmHg), medium (130-160/80-100 mmHg), and high (>160/100mmHg) BP categories. The mean BP difference between PG-800B11 and observers in the 85 participants was -0.6±5.0 mmHg for SBP and -0.6±4.5 mmHg for DBP; thus, the device also fulfilled the requirements of the Association for the Advancement of Medical Instrumentation (AAMI). Conclusion: The Pangao PG-800B11 passed all requirements of the ESH-IP revision 2010 and achieved A/A grade of the BHS protocol across a wide range of BPs. © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins.


Chen X.-C.,117 Hospital of PLA | Liu M.,117 Hospital of PLA | He D.,117 Hospital of PLA | Yue C.-H.,117 Hospital of PLA | And 3 more authors.
National Medical Journal of China | Year: 2013

Objective: To evaluate the efficacies of treating osteonecrosis of the femoral head (ONFH) with percutaneous retaining catheterization. Methods: A total of 85 patients (106 hips) of ONFH underwent percutaneous retaining catheterization with self-made instrument. There were stage I (n=32, 40 hips), stage II (n=41, 50 hips), stage III (n=7, 9 hips) and stage IV (n=5, 7 hips) by Ficat and Arlet classification. The selection criteria include bone marrow edema (BME) of the femoral head and neck and joint fluid on magnetic resonance imaging (MRI). The percent method (%) of Orthopedics Branch of Association of Chinese Medical Association was used for evaluating the efficacies of ONFH with retained femoral head. A follow-up period of 2-10 years was conducted with plain radiograph. The standard was as follows: > 90, excellent; 75-89, good; 60-74, passable; < 60, bad. The combination of excellent and good denoted obvious effect rate; passable for valid rate; bad for invalid rate. The historical core decompression was used as control group. And χ2 test was used for statistical analysis (P < 0.05). Results: The obvious effect rate was 88% (35/40), 74% (37/50), 22% (2/9), 14% (1/7), the valid rate 7% (3/40), 12% (6/50), 22% (2/9), 14% (1/7) and the invalid rate 5% (2/40), 14% (7/50), 56% (5/9), 72% (5/7) respectively in Ficat I, II, III and IV stage. No statistically significant differences existed between Ficat I and II stage (P > 0.05). But there were statistically significant differences in other groups (P < 0.01). Conclusion: Percutaneous retaining catheterization is efficaciously treating ONFH in Ficat I and II stage and it may also be used for ONFH in Ficat III and IV stage. Copyright © 2013 by the Chinese Medical Association.


Liu Y.,117 Hospital of PLA | Mei W.-Q.,117 Hospital of PLA | Li Z.-C.,117 Hospital of PLA | Zhong M.-D.,117 Hospital of PLA | And 3 more authors.
Medical Journal of Chinese People's Liberation Army | Year: 2014

Objective To investigate the effect of melatonin (MLT) on protein and mRNA expression of leptin (Lep) in subcutaneous fat tissue in insulin resistance (IR) rats. Methods Thirty seven Sprague-Dawley (SD) rats were randomly divided into model group (n=27) and control group (CN group, n=10). Rats in model group were fed with high glucose diet for 6 weeks. Twenty rats having developed IR in the model group were further randomly divided into two groups: IR group (n=10) and melatonin group (MLT group, n=10). Rats in CN group and MLT group were fed with 10mg/(kg.d) of standard chow or MLT, respectively, for 6 weeks from the beginning of the 7th week. At the end of the 12th week, the subcutaneous fat tissue was harvested from bilateral inguinal areas of the rats for the evaluation of the protein and mRNA expression of Lep by immunohistochemistry and RT-PCR. Results Systolic blood pressure (SBP), fasting serum leptin (Lep), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), malondialdehyde (MDA) and homeostasis model assessment insulin resistance (HOMA-IR) were significantly lower (P<0.01), while the serum superoxide dismutase (SOD) was significantly higher in MLT group compared with those in IR group (P<0.01). The levels of fasting plasma glucose (FPG) and 2-hour postprandial plasma glucose (2hPPG) remained in normal range, and the body weight showed no significant difference among the three groups (P>0.05). The protein and mRNA expressions of Lep in subcutaneous adipose tissue were significantly higher in IR group than in CN group (P<0.01), while they were significantly lower in MLT group than in IR group (P<0.01). Conclusion MLT may improve IR and the status of oxidation stress, and inhibit the over expression of Lep protein and mRNA in subcutaneous fat tissue in the high-glucose diet-induced IR rats.


Yang Y.,117 Hospital of PLA | Zheng J.,117 Hospital of PLA | Lou S.,117 Hospital of PLA
International Journal of Clinical and Experimental Medicine | Year: 2015

Objective: To evaluate the medium to long-term curative effects of surgical long segmental fixation and fusion in degenerative scoliosis (DS). Patients and methods: From January 2001 to December 2011, 56 DS patients underwent long segmental fixation and fusion. Clinical data, including visual analogue scale (VAS) scores, Oswestry disability index (ODI), lumbar lordosis angles, coronary Cobb angles and postoperative complications were followed up for 2 to 12 years postoperatively. Results: VAS and ODI scores were significantly improved 1 year postoperatively compared to the preoperative values (P = 0.000). Coronary Cobb angles were significantly improved three months postoperatively (P = 0.001) but ≥ 1 year after surgery there was no further significant improvement compared to the preoperative values (P = 0.585). The lumbar lordosis angle was not significantly changed postoperatively (P > 0.05). Conclusions: Favorable medium to long-term curative effects can be achieved by long segmental fixation and fusion. Ideally, the fixation and fusion segments should be longer than the segments affected by scoliosis. The restoration of the lumbar lordosis angle is the key to rebuilding sagittal balance, which is closely correlated with a patient’s clinical symptoms and quality of life. © 2015, E-Century Publishing Corporation. All rights reserved.


Liu Y.,117 Hospital of PLA | Li Z.-C.,117 Hospital of PLA | Chen J.-B.,117 Hospital of PLA | Yu T.-T.,117 Hospital of PLA | And 2 more authors.
Medical Journal of Chinese People's Liberation Army | Year: 2015

Objective To observe the clinical effect of small dose of colchicine combined with glucocorticoid for acute gouty arthritis. Methods Ninety-two patients with acute gouty arthritis were equally and randomly divided into small doses of colchicine combined with dexamethasone treatment group (treatment group) and conventional large dose colchicine treatment group (control group) between January 2009 and December 2013. The articular lesion scoring and clinical efficacy evaluation were performed at 3, 6, 12, 24, 48, and 72h after treatment. Erythrocyte sedimentation rate (ESR), white blood cells, hepatorenal function and glomerular filtration rate (GFR) were determined before and 72h after treatment respectively. The gastrointestinal adverse events and recurrence rate were observed within one month after treatment. Results The articular lesion scores were significantly decreased at 6, 12, 48, and 72h after treatment in treatment group compared with control group (P<0.05 or P<0.01). Compared with that of pre-treatment, ESR and white blood cell count were decreased significantly 72h after treatment (P<0.05), but there was no statistical difference between the two groups (P>0.05). Serum uric acid, glutamic-pyruvic transaminase in serum (SGPT), and GFR did not show any change before and 72h after the treatment, and there was also no significant difference between groups (P>0.05). The incidence of gastrointestinal adverse events were obviously higher in control group (76.1%) compared with that of the treatment group (P<0.05), and the differences was statistically significant. There was no statistical difference in recurrence rate between the control group and treatment group after a follow-up of one month. Conclusions Compared with conventional large dose colchicine, small dose of colchicine combined with dexamethasone can more rapidly and effectively control acute gouty arthritis, with good tolerability and safety, thus being worthy of popularization clinically. © 2015, People’s Military Medical Press. All rights reserved.


Zong Y.,Zhejiang University | Yu X.,Zhejiang University | Zhu M.,117 Hospital of PLA | Lu S.,Zhejiang University
Journal of Soils and Sediments | Year: 2014

Purpose: Soils have a wide range of pore size distribution (PSD) from nanometer to micrometer scale. The detailed characterization of soil pore structure in a wide pore size range is important for understanding the soil processes. In this study, three different techniques are used to quantitatively describe the soil pore characteristics in a wide pore size range and to evaluate whether different pedogenic processes affect porosity and PSD of the soils. Materials and methods: The four different types of soils: black soil (BS, Udic Agriboroll), Shajiang black soil (SBS, Aquic Pelludert), paddy soil (PS, Aeric Endoaqualf), and latosolic red soil (LRS, Typic Kandiudults) were selected to represent the most important soil types in China. A combination technique of nitrogen adsorption isotherm (NAI), mercury intrusion porosimetry (MIP), and synchrotron-radiation-based X-ray computed microtomography (SR-mCT) was used to describe the pore structure characteristics including the porosity, PSD, and pore geometry in the soils. Results and discussion: The NAI method revealed larger differences in the Brunauer-Emmett-Teller (BET) surface area and 0.002–0.15 μm pore volume for the studied soils. The latosolic red soil (LRS) has the largest volume of 0.002–0.15 μm pore, while BS has the smallest. The PSD determined by MIP exhibited that BS and paddy soil (PS) had multimodal peaks, indicating the existence of a more heterogeneous pore system. The PSD from LRS and SBS exhibited a single, sharply defined peak at a pore diameter from 0.02 to 0.04 and 0.01 to 0.06 μm, respectively. The volume of the >3.7 μm pores determined by the SR-mCT method was in the order of BS (18.2 %) > PS (10.6 %) > LRS (7.2 %) > SBS (5.4 %). The pore shape measured by SR-mCT has an obvious difference in pore system for different soils. Regular pores were more frequent in BS than in SBS, PS, and LRS. Conversely, lower percentage of irregular pores was found in the BS. Conclusions: The combination of NAI, MIP, and SR-mCT techniques can quantify the porosity and PSD of soils over a wide range of pores. For the overlapping pore region, the pore volume determined by the MIP and SR-mCT agreed well. Our results indicated that pedogenic processes can greatly influence the soil pore structure both in terms of PSD and pore shape. © 2014, Springer-Verlag Berlin Heidelberg.


PubMed | 117 Hospital of PLA
Type: Journal Article | Journal: Zhonghua yi xue za zhi | Year: 2013

To evaluate the efficacies of treating osteonecrosis of the femoral head (ONFH) with percutaneous retaining catheterization.A total of 85 patients (106 hips) of ONFH underwent percutaneous retaining catheterization with self-made instrument. There were stage I (n = 32, 40 hips), stage II (n = 41, 50 hips), stage III (n = 7, 9 hips) and stage IV (n = 5, 7 hips) by Ficat and Arlet classification. The selection criteria include bone marrow edema (BME) of the femoral head and neck and joint fluid on magnetic resonance imaging (MRI).The percent method(%) of Orthopedics Branch of Association of Chinese Medical Association was used for evaluating the efficacies of ONFH with retained femoral head. A follow-up period of 2-10 years was conducted with plain radiograph.The standard was as follows: >90, excellent; 75-89, good; 60-74, passable; <60, bad. The combination of excellent and good denoted obvious effect rate; passable for valid rate; bad for invalid rate.The historical core decompression was used as control group.And (2) test was used for statistical analysis (P < 0.05).The obvious effect rate was 88%(35/40), 74%(37/50), 22%(2/9), 14%(1/7), the valid rate 7%(3/40), 12% (6/50) , 22% (2/9), 14%(1/7) and the invalid rate 5%(2/40), 14% (7/50) , 56% (5/9), 72% (5/7) respectively in Ficat I, II, III and IV stage. No statistically significant differences existed between Ficat I and II stage (P > 0.05) .But there were statistically significant differences in other groups (P < 0.01) .Percutaneous retaining catheterization is efficaciously treating ONFH in Ficat I and II stage and it may also be used for ONFH in Ficat III and IV stage.


PubMed | Central South University and 117 Hospital of PLA
Type: | Journal: Journal of orthopaedic surgery and research | Year: 2015

With the aging of the population, degenerative scoliosis (DS) incidence rate is increasing. In recent years, increasing research on this topic has been carried out, yet biomechanical research on the subject is seldom seen and in vitro biomechanical model of DS nearly cannot be available. The objective of this study was to develop and validate a complete three-dimensional finite element model of DS in order to build the digital platform for further biomechanical study.A 55-year-old female DS patient (Suer Pan, ID number was P141986) was selected for this study. This study was performed in accordance with the ethical standards of Declaration of Helsinki and its amendments and was approved by the local ethics committee (117 hospital of PLA ethics committee). Spiral computed tomography (CT) scanning was conducted on the patients lumbar spine from the T12 to S1. CT images were then imported into a finite element modeling system. A three-dimensional solid model was then formed from segmentation of the CT scan. The three-dimensional model of each vertebra was then meshed, and material properties were assigned to each element according to the pathological characteristics of DS. Loads and boundary conditions were then applied in such a manner as to simulate in vitro biomechanical experiments conducted on lumbar segments. The results of the model were then compared with experimental results in order to validate the model.An integral three-dimensional finite element model of DS was built successfully, consisting of 113,682 solid elements, 686 cable elements, 33,329 shell elements, 4968 target elements, 4968 contact elements, totaling 157,635 elements, and 197,374 nodes. The model accurately described the physical features of DS and was geometrically similar to the object of study. The results of analysis with the finite element model agreed closely with in vitro experiments, validating the accuracy of the model.The three-dimensional finite element model of DS built in this study is clear, reliable, and effective for further biomechanical simulation study of DS.

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